Sunday, December 07, 2014

Xenon Hof Memory Programming.

Xenon Hof Memory Programming


Andre Willers
7 Dec 2014
Synopsis :
Xenon Hof technique enables programming of the body memory system , including immune system . It also means Mars has a biosphere .

Discussion :
0.Overview :
Xenon evolved into forgetty role to prevent maximumEffort-paralysis by partially zapping memory of all systems .
This includes immune , brain  and epigenetic systems .
The epigenetics is Surprising , but it has to be , since many memory systems are epigenetic in nature .
It had to be scarce and , well, noble .
Used with MSM and Melatonin .
See para 7 below .
 
1.The Hof Technique :
Simple exercises taught in 10 days that had a marked effect on autoimmune responses .
See Appendix A and Appendix B

2.Xenon for bad memories
See Appendix C .
This is further indicated in the use of Xenon in athletic doping . See Appendix F
As Tim Noakes has found , expectation of stress based on memory degrades maximal performance at an unconscious level .
Something like bodily PTSD .
  
3.The missing Xenon .
See Appendix E . On both Earth and Mars the atmospheric concentration of xenon does not match solar meteor concentrations .
Where is the missing xenon ?

Since xenon seems to play a crucial role in some important biological processes (Appendices C and F) , I strongly suspect that the missing xenon is hiding in plain sight in the biosphere .
But in very , very low concentrations spread out amongst the nervous systems .

It seems that no one has really looked for it there .
On the web there is no data  about xenon presence in the body , yet we know that is  there .
The evolutionary pathways used in Appendices C , F must have had xenon .
 
4. Mars
If this argument is correct , it means that Mars has a biosphere . Nearly certainly underground lakes and river networks with lifeforms .
So pack your biohazard suit when visiting .
 
5.So how does the body sequester xenon from the atmosphere ?
The Hof process is essentially 3 fold  :  Meditation , variation in breathing , exposure to temperature variants . See Appendix B

Take a step back to bacterial level . Scratch meditation .
This leaves breathing and temperature .
Hyperventilation /retention (O2 /CO2/PH flux) followed by rapid cooling (metabolic stand-down marker)

This triggers the activation of some heat-shock proteins that enzymatically copies the fractional-distillation of xenon from the atmosphere . See Appendix D
Well within bio capability .
Since this involves stand-downs in bio rates , it would involve some variant of the hibernation system to be activated .
So ,  MSM is an adjuvant to Xenon .
Anaesthesiologists  take note .

6.Termination .
The process can be terminated by Melatonin . See http://andreswhy.blogspot.com/2011/06/melatonin-and-dinosaurs.html
 
7.Xenon Hof Express Method for humans .
Dial down maximal pain memories in a hurry .

7.1 Take MSM . Wait about 10 minutes .
7.2 Hyperventilate (with Xenon if available) :about 12 breaths .
7.3 Activate diving reflex by holding breath as long as possible while plunging your face alternately into a basin of ice water and a basin of scorching hot water .
7.4 This will activate xenon extraction mechanism . Memory decrease follows . PTSD betterment .

7.5 Using it for maximal endurance like running means your memory of all things will also deteriorate . So don’t do this the night before the exam .
With autoimmune diseases just do it for 12 breaths and terminate with melatonin (pill)
7.6 Terminate with Melatonin . (Sleep)

8.Is there any way to enhance memory ?
Not that I can see . It is one of the reasons why Xenon evolved into the role .
The best you can do is prevent unnecessary memory loss with a Xenon antagonist . But xenon is noble , and cannot have a chemical antagonist . QED .
Nature really does not like too high efficiencies .
And a very efficient memory of anykind seems high on her zap list .

9.Try it .
It should help for edema’s , high blood pressure , high blood sugars , some arthritis , etc .

Who goes here ?

Andre

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Appendix A
Hof technique .
Scientific Proof:
Exercises Wim Hof Method influence the autonomous nervous system and immune system
With the help of simple techniques like breathing exercises, meditation and repeated exposure to cold you can activate the autonomic nervous system and inhibit the response of your immune system. Researchers from the Radboud University Medical Center have provided the first scientific evidence for this in an article published yesterday in the leading scientific journals PNAS and Nature.
A well-functioning immune system protects our body from pathogens. But sometimes the immune response is too pronounced or persistent. This can lead to the development of autoimmune diseases such as rheumatism. Our immune system is controlled, amongst other things, by the autonomic nervous system, which is involved in the ‘fight-or-flight response’. It was always thought that we could not voluntarily influence either the immune system or the autonomic nervous system. However, experiments from intensive care researcher Dr. Matthijs Kox and Professor of Experimental Intensive Care Medicine Peter Pickkers now demonstrate that this is possible using certain techniques. Importantly, the researchers emphasize that it has not yet been investigated whether these techniques could be effective in patients.

Training Wim Hof Method
‘Iceman’ Wim Hof trained twelve healthy young male volunteers for ten days in a number of specific techniques. The training partly took place in Poland where the volunteers learned breathing and meditation exercises and to walk in short trousers through the snow and swim in ice-cold waters. Back in the Netherlands, scientists gave both the twelve trained subjects and twelve healthy non-trained volunteers an injection containing endotoxin, a component from the cell-wall of bacteria that elicits a response from the immune system. Pickkers: “By administering a dead bacterial component we are actually fooling the body. The immune system responds as if living bacteria are present in the blood stream and produces inflammatory proteins. As a result of this the subjects develop symptoms such as fever and headache. We can therefore use this approach to investigate the immune system of humans.”
Stress hormone
Kox: “The trained men produced more of the hormone epinephrine as a result of the techniques they had learned.” Epinephrine is a stress hormone that is released during increased activity of the sympathetic nervous system and it suppresses the immune response. “We indeed observed that in the trained subjects the release of inflammatory proteins was attenuated and that they experienced far less flu-like symptoms,” says Kox.
Previous iceman research
Iceman Wim Hof is famous for his various records related to cold-exposure. In his own words he can realize these by influencing his autonomic nervous system. In 2011, researchers from Radboud university medical center investigated the response of Hof’s body to an endotoxin injection while he was practicing the techniques he had developed himself. He was found to produce less than half the quantity of inflammatory proteins than healthy volunteers who had not mastered his method. Furthermore, he exhibited almost no flu-like symptoms. The result was so remarkable that the researchers decided to carry out a follow-up study.
Publication in PNAS – Matthijs Kox, Lucas van Eijk, Jelle Zwaag, Joanne van den Wildenberg, Fred Sweep, Hans van der Hoeven and Peter Pickkers, ‘Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans’, Proceedings of the National Academy of Sciences, 5 May 2014. Or read the publication in Nature Magazine
If you like to discover the method? Please check out the 10-week online video course
This follow-up study could in part be realized due to a serendipity grant from the Dutch Arthritis Foundation.


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Appendix B
The experiment , including training regimen .
http://www.pnas.org/content/early/2014/04/30/1322174111.abstract
Significance
Hitherto, both the autonomic nervous system and innate immune system were regarded as systems that cannot be voluntarily influenced. The present study demonstrates that, through practicing techniques learned in a short-term training program, the sympathetic nervous system and immune system can indeed be voluntarily influenced. Healthy volunteers practicing the learned techniques exhibited profound increases in the release of epinephrine, which in turn led to increased production of anti-inflammatory mediators and subsequent dampening of the proinflammatory cytokine response elicited by intravenous administration of bacterial endotoxin. This study could have important implications for the treatment of a variety of conditions associated with excessive or persistent inflammation, especially autoimmune diseases in which therapies that antagonize proinflammatory cytokines have shown great benefit.
Abstract
Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervous system attenuates the innate immune response. However, both the autonomic nervous system and innate immune system are regarded as systems that cannot be voluntarily influenced. Herein, we evaluated the effects of a training program on the autonomic nervous system and innate immune response. Healthy volunteers were randomized to either the intervention (n = 12) or control group (n = 12). Subjects in the intervention group were trained for 10 d in meditation (third eye meditation), breathing techniques (i.a., cyclic hyperventilation followed by breath retention), and exposure to cold (i.a., immersions in ice cold water). The control group was not trained. Subsequently, all subjects underwent experimental endotoxemia (i.v. administration of 2 ng/kg Escherichia coli endotoxin). In the intervention group, practicing the learned techniques resulted in intermittent respiratory alkalosis and hypoxia resulting in profoundly increased plasma epinephrine levels. In the intervention group, plasma levels of the anti-inflammatory cytokine IL-10 increased more rapidly after endotoxin administration, correlated strongly with preceding epinephrine levels, and were higher. Levels of proinflammatory mediators TNF-α, IL-6, and IL-8 were lower in the intervention group and correlated negatively with IL-10 levels. Finally, flu-like symptoms were lower in the intervention group. In conclusion, we demonstrate that voluntary activation of the sympathetic nervous system results in epinephrine release and subsequent suppression of the innate immune response in humans in vivo. These results could have important implications for the treatment of conditions associated with excessive or persistent inflammation, such as autoimmune diseases.
·         LPS

·         cathecholamines

·         cortisol

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·         Appendix C

Xenon Impairs Reconsolidation of Fear Memories in a Rat Model of Post-Traumatic Stress Disorder (PTSD)
·         Edward G. Meloni mail,

·         Timothy E. Gillis,

·         Jasmine Manoukian,

·         Marc J. Kaufman
·          
Abstract
Xenon (Xe) is a noble gas that has been developed for use in people as an inhalational anesthestic and a diagnostic imaging agent. Xe inhibits glutamatergic N-methyl-D-aspartate (NMDA) receptors involved in learning and memory and can affect synaptic plasticity in the amygdala and hippocampus, two brain areas known to play a role in fear conditioning models of post-traumatic stress disorder (PTSD). Because glutamate receptors also have been shown to play a role in fear memory reconsolidation – a state in which recalled memories become susceptible to modification – we examined whether Xe administered after fear memory reactivation could affect subsequent expression of fear-like behavior (freezing) in rats. Male Sprague-Dawley rats were trained for contextual and cued fear conditioning and the effects of inhaled Xe (25%, 1 hr) on fear memory reconsolidation were tested using conditioned freezing measured days or weeks after reactivation/Xe administration. Xe administration immediately after fear memory reactivation significantly reduced conditioned freezing when tested 48 h, 96 h or 18 d after reactivation/Xe administration. Xe did not affect freezing when treatment was delayed until 2 h after reactivation or when administered in the absence of fear memory reactivation. These data suggest that Xe substantially and persistently inhibits memory reconsolidation in a reactivation and time-dependent manner, that it could be used as a new research tool to characterize reconsolidation and other memory processes, and that it could be developed to treat people with PTSD and other disorders related to emotional memory.

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Appendix D

Xenon

Occurrence and production[edit]
Xenon is a trace gas in Earth's atmosphere, occurring at 87±1 parts per billion (nL/L), or approximately 1 part per 11.5 million,[49] and is also found in gases emitted from somemineral springs.
Xenon is obtained commercially as a byproduct of the separation of air into oxygen and nitrogen. After this separation, generally performed by fractional distillation in a double-column plant, the liquid oxygen produced will contain small quantities of krypton and xenon. By additional fractional distillation steps, the liquid oxygen may be enriched to contain 0.1–0.2% of a krypton/xenon mixture, which is extracted either via adsorption onto silica gel or by distillation. Finally, the krypton/xenon mixture may be separated into krypton and xenon via distillation.[50][51] Worldwide production of xenon in 1998 was estimated at 5,000–7,000 m3.[52] Because of its low abundance, xenon is much more expensive than the lighter noble gases—approximate prices for the purchase of small quantities in Europe in 1999 were 10 /L for xenon, 1 €/L for krypton, and 0.20 €/L for neon;[52] the much more plentiful argon costs less than a cent per liter.

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Appendix E
Mystery of missing Xenon
Xenon, the second heaviest of the chemically inert noble gases, has gone missing. Our atmosphere contains far less xenon, relative to the lighter noble gases, than meteorites similiar to the rocky material that formed the Earth.
The missing-xenon paradox is one of science’s great whodunits. Researchers have hypothesized that the element is lurking in glaciers, minerals or Earth’s core, among other places.
“Scientists always said the xenon is not really missing. It’s not in the atmosphere, but it’s hiding somewhere,”
Indeed .
It seems to be hiding in the biosphere .
Since Mars has the same mystery , it strongly indicates that Mars has a biosphere .

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Appendix F
Doping
XENON AND SPORTS PERFORMANCE ENHANCEMENT
Research suggests that breathing xenon boosts the body’s production of a protein known as HIF1 Alpha (HIF1A). If you’d like to learn more about HIF1A and how it works you can read these articles we published last year, but the simplified version is that HIF1A seems to act by stimulating the production of other compounds in the body, including EPO.
As a quick reminder, EPO is a hormone that regulates the body’s production of red blood cells. Stimulate the production of EPO and you get more red blood cells; get more red blood cells and you increase the blood’s ability to transport oxygen around the body. An increased ability to transport oxygen may theoretically lead to an increase in athletic performance, particularly when we’re talking about high endurance sports such as competitive cycling. (Click here to read more about how EPO works).
While much research has been done on xenon gas and its use as an anaesthetic, little has been done on its ability to improve athletic performance. But in Russia there are those that swear by xenon and its benefits for endurance athletes.
BUT DOES XENON IMPROVE ATHLETIC PERFORMANCE?
The 2010 ZAO Atom-Med Center presentation mentioned above cites research which tested the athletic performance of a number of professional athletes pre- and post-xenon use, including the use of placebos in the case of some athletes. The research reportedly showed that MedXenon, a brand of xenon gas mixture owned by the ZAO Atom-Med Center, works within just five minutes of application and has a lasting effect of up to 80 hours.
While it’s difficult to assess how rigorous the research testing is in this case — particularly given the product being tested is owned by the agency involved in manufacturing and selling it — the Russian government both acknowledges the work being done at ZAO Atom-Med Center and has supported the use of xenon for Russian athletes. 

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