Saturday, July 02, 2011

Melted Cheese II

Melted Cheese II
Andre Willers
2 Jul 2011

Synopsis :
Acrylamides and bacterial quorums might be linked.

Discussion :
See http://andreswhy.blogspot.com
"Diabetic Peripheral Neuropathy and Acrylamide" Jun 2006
"Diabetic Peripheral Neuropathy and Acrylamide 2 " Jun 2006

But what about acrylamide? Could residual sugars be present?
Yes . Lactose could generate acrylamide above 120 Celsius , so use cheeses with zero or very small carbohydrate content (like mozzarella – Pizza!) . See product contents description . There are quite a number of low-carb cheeses around .

Do not add sugars (like figs , etc) during the heating process .

I suspect a linkage between acrylamide and the "melted cheese " argument .
But it might be true , (from basics or accidental) or untrue0 , (purely in my mind .)

More information is needed .

The problem is :
1. The "melted cheese" argument is about bacterial quorums .
An old system using very basic chemical messengers .
2.Acrylamide is about neuronal toxins , involving heating over 120 C . Much newer .

One way would be for acrylamide to interfere with the original chemical messengers . If some of these messengers had been roped into building axons , then we would have a connection .
But there is no evidence . It is stretching it , even for me .

But the possibility that such a simply produced compound as acrylamide can affect bacterial quorums should be vigorously pursued .

If it is true , there must be many others of the same class .
Apart from new classes of medicines and antibiotics , there is a strong possibility that many old ones (especially involving heating in the presence of sugars – and just about all cooking) can have unpredictable or deletrious effects .

"There is Death in the pot !" Bible

Andre

Thursday, June 30, 2011

Melted Cheese.

Melted Cheese.
Andre Willers
1 Jul 2011

This argument is for my benefit , not yours .
How much cheese can I safely eat ?
As much as I like , as long as it is heated above 129 Celsius .

If the non-angiosperm (especially fungi) markers exceed 1/3 , then the intestinal flora will start switching genes to favour fungi . (Your gut does not watch CNN)
You get fungal infections .Regardless of immune system responses . The immune system actually starts protecting fungi . Serious trouble .

http://en.wikipedia.org/wiki/Rennet
Bovine chymosin is now produced recombinantly in E. coli,Aspergillus niger var awamori, and K. lactis as alternative resource. The gene is found in humans (on chromosome 1), but it is notexpressed.

Notice there are two links between the halves of the molecule . The energy levels between them are not equal . One is about Pasteur level (40-50 centigrade) .The other at about 120 centigrade (if little sugar is present) .

Ghee .
Clarified butter (ie boiled for a long time) The best ghee is pressure boiled(about 120 centigrade ) . This keeps a long time . Not because it is so pure . Because the chymosin molecule that renders it usable has been broken .
Bacteria can't eat it .But humans can . A significant asymmetry .
Foamed ghee and garlic (allicin as per previous posts) will have significant effects .

Bah .
A thick slice of cheese over a thin slice of melba toast , (ratio 2/3 to1/3) done in a microwave until the cheese bubbles will destroy any markers .

Mushrooms heated completely through at over 120 Centigrade should be safe .

Thick , melted cheese doe's the trick .

Andre .

Epicanthic Folds and Carbon Monoxide

Epicanthic Folds and Carbon Monoxide.
Andre Willers
29 Jun 2011

Synopsis:
Fats in epicanthic folds , spread over the eyeball , acts as warning for dangerous buildup of carbon monoxide . This will be evolutionary dominant (like nosehairs for smoke)

Discussion :
The mutation package was part of the changes to the refugees in the Tibetan Plateau .
Not only changes to the oxygen exchange mechanism to tolerate high altitudes , but also a sensor about dangerous build-up of carbon monoxide .

The carbon monoxide comes from the use of charcoal (low weight) in a low-oxygen environment (ie high altitude) .
It was also cold . So , environments had to be sealed and heated .
High altitude was crucial . Low partial pressure of oxygen . The CO effect would be more marked .

How would the warning surface ?
I do not know , but theorize that it would be a prickling and irritation of eyeball as CO interact with epicanthic fats to form irritants .

The children with certain types of fats in their epicanthic folds had very strong advantages . Like survival .

Their descendants populated the lowlands ( Han , Mongols) . In yurts and snowed in Chinese houses , if their eyes started to prickle , they got out and avoided CO poisoning .

Human perverseness :
Their descendants liked CO : ie smoking . Got nothing to do with nicotine .
You would get the same reaction by blowing a metered CO concentration over the eyeballs .

Andre

Wednesday, June 29, 2011

Why are you not an octopus ?

Why are you not an octopus?
Andre Willers
29 Jun 2011

"Less is more"

Synopsis :
A bony endoskeleton enforced a limitation on the degrees of freedom of movement . This freed up neurons for central utilization of mirror neurons . Ie culture .

Discussion :
Octopi evolved long before mammals and dinosaurs .
Having no endo or ecto skeleton , every movement had to be controlled , using up huge neural resources .
Present octopi have about 500 million neurons (about dog size) , but a whopping 60% of that is used for control of the tentacles and body .
This is because they had no bones . Every cm of movement had to be controlled .

A further about 32% is used for control of the visual , and optic and photo-mimic cells This leaves about 8% for the brain (a central cartiligeous bound organ) for central direction .
(Source: NewScientist 11 Jun 2011 p39)

We would expect them to have had mirror neurons based in the 32% visual , and optic and photo-mimic cells .
But with such a small neural reserve left after necessities of muscular control , culture did not develop .

And that is why you are not an octopus .

The Ape Conjecture :
A mutation resulting in tailless monkeys (ie apes) freed up the neurons that controlled the tail-tentacle . These were colonised by mirror-neurons , resulting in Culture .

Note taildocking or tailcontrol in domesticating animals .
This would seem to have a neurological basis . The phenotype for domestication involves an erect and nearly immobile tail , only moving in response to mirror-neuron excitation .

In the domestication of silver foxes this took only 8 generations . Presumably , with the ape-ancestors of humans , it would have been equally as fast .

Human body language :
It is amusing to note that shifting weight from one foot to another is interpreted by some very deep levels of neurons as a tail-wagging , meaning "I can see your viewpoint . I am not unfriendly" . Hence , at cocktail parties everybody is standing and circulating .
Or soldiers stand at attention , signifying disregard of the other party's interests .

The evolutionary trap of skulls .
As octopi were trapped by the necessity of limb control , bony animals were trapped by the necessity of protecting the central brain . The skull . This limited the number of neurons .
Monkeys traded their tails for extra ape-mirror neurons to kickstart language and culture . The Data-processing went outside the skull into the culture .

The Culture trap .
Also known as the 150 person or Family trap . The maximum number of people you could afford to care about .
This has been the basis of recorded history . Dynasties , families ,etc .

But the ceiling has been broken .
This has been tried (and done) before in communities like monasteries . They had vertical integration , but lacked long-range , horizontal integration .
This is why Facebook is so important , and expanded so fast .
It will be superseded and replaced . Twitter already has to a certain extent .

It does not matter .
The ceiling has been broken .
There is no going back .
New patterns will replace the old ones if humans survive .

"Dem bones , dem bones"
Andre

Saturday, June 25, 2011

Music and Longevity

Music and Longevity .
Andre Willers
25 Jun 2011

Synopsis :
We look at DNA-RNA complementarity , with pattern compression (density) stimulation .

Discussion :
Telomeres have the structure in DNA of
TTA GGG (DNA)
AAT CCC (DNA complementary)
AAU CCC (RNA complementary )
AA UC CC (RNA : Music for "The End" rearrangement in pairs of two )

The last stimulates RNA production that inhibits telomere production .
The end , indeed .(A type of iRNA , old age and the yuckkies)

So :
We can stimulate telomere production by DNA reverberation via pressure waves .
TT AG GG (DNA)
Or inhibit it by
AA UC CC (RNA)
.
Resonances are critical , but we can start with the third element (A or U) .
DNA is lower energy , and more stable .(Evolutionary reasons)

So , the third element is crucial . If it is emphasized (like in the musical "end" ) , antithetical RNA is stimulated . Telomere production is inhibited and you get older .

But can the music make you younger ?
Can it stimulate telomere production ?
Yes .
As long as the third element of the beat is of much lower frequency . The exact resonances of Adenine and Cytosine in various water concentrations are needed . The same for the others if you want a music that really resonates . This can be designed .

Gut Thumping :
Just hit your stomach in a certain rhythm .
You can live longer by Gut Thumping .
The pattern is :
1.Thump , 2.Thump , 3.Deep breath , Thump , Exhale , draw on CO generator 4.Thump . 5.Thump . 6.Thump

You only need about one breath in six , and you need a CO level (not just CO2)
Something your Guru neglected to mention to you .
The CO level decreases the energy of the inhalation . This stimulates Telomere production .
Of course you can use precisely metered CO inhalers , or Camel Filter.

Precisely metered H2S
This , combined with the procedures above , can give an extended lifespan to Homo
Sapiens . In the order of 25 000 years (the accidental death ceiling)
How boring . You will need a small memory to make this meaningful .

An amusing thought .
Are immortals contaminating the gene-pool with boredom via Alzheimers ?

I can intuit that H2S therapy will resolve most Alzheimer problems .(The sulfur molecules )

Why ?
H2S freezes biological activity . This includes laying down of memories, both long-term and short term . The concentrations matter .

And eggs do not get rotten any more . Present humans are never exposed to H2S and pay the price with Alzheimers .

"Remembering too much , they forget everything "
A precise molecular description
Happy people will have no problem with unpeeling of myeloid memories via H2S therapy . But unhappy people with bad memories will re-suffer .

May they have their joy of Hoffman .

Andre

How to predict earthquake damage .

How to predict Earthquake Damage .
Andre Willers
25 Jun 2011

"Fight only after you have won" Sun Tsu

Synopsis :
Predict only after the event . It takes a slow speed for the quake effects to travel , but lightspeed for the information . The information can be collated , integrated and distributed nearly instantaneously using GPS and smartphone apps before the quake arrives from the epicenter .

Discussion :
A Californian Killer-App .
GPS in phones and other things have both lateral and vertical capability . Sudden mass movement can be recognized (app) , then broadcast long-range (small world network model ) .

In other words an earthquake can be recognized at the epicenter and warnings sent to neighbouring cellular networks long before the actual earthmovement arrives there . A 100 % prediction .

The magnitude , ETA and Tsunami effects can be built into the app .
(A trivial set of rules)

Experience in the last set of quakes and tsunami's have shown that even 10 seconds of warning can have dramatic effect on the human death rate .

The unzipping of the Pacific Rim of Fire is proceeding roughly on schedule .
(Aleutian Earthquake of 7.4 on 23 Jun 2011)
See http://andreswhy.blogspot.com "Los Angelos Earthquake Warning" Mar 2011
The unzipping is expected to proceed faster along longitudes (see arguments about helical plasma plumes , barycenter , etc) .
The expected Big One in California is within the next 6 months .

Earthquake App on your Cellphone .
This can give a directed warning , sufficient for large survival rates .
Profitable too .
I would certainly be willing to pay a small fee for such a service in an area like California . Multiply by millions .

GeoCaching
A sport that hides GPS systems connected to the grid in the most inaccessible places they can think of . A free earthquake monitoring and warning service . To be encouraged .
See www.geocaching.com and www.opencaching.com

Why wait till the quake reaches the surface ?
Most epicenters are kilometers below the surface , with the same differentials in transmission speed .
But how to measure them ?

Gravity !
A 9 quake like in Japan recently , had significant gravitational effects , measurable in satellite orbits . This includes GPS satellites , where measurements can be made to a very fine degree , using time-differentials .
Co-ordinate this with geo-magnetic measurements using a genetic algorithm , and we can get a by-damn fine damage predictive system into hours .
All nearly 100% . Postdictive .
And mostly done real-time using GPS time-differentials .

These can be linked into the phone apps , leading to hours of warning time .

Money :
Really serious money can be made by being the first effective warning service providers .

Time for the Free-enterprise model to put up or shut up .
You have 2 months time in California and the USA .

Why ?
Mr Murphy :
The worst possible time for the Big One in California is around Aug 2 , 2011 .
See http://andreswhy.blogspot.com "Financial Crash 2 Aug 2011" Jun 2011

If you can't predict , postdict with a long lead time .

Andre .

Thursday, June 23, 2011

Financial Crash on Aug 2 , 2011

Financial Crash on 2 Aug 2011
Andre Willers
23 Jun 2011

Synopsis :
Special interests will cause the USA to gridlock on extension of debt ceiling . The subsequent USA default will dwarf Greek default and cause global financial failures and lock-downs .
Dear Readers are advised to seriously consider exposure risks .
(Get out of Dodge City if you don't want to end up on boot hill.)

Discussion
1.The USA runs out of money on 2 Aug 2011 .
It has a legal debt ceiling (14.7 $Trillion) that will be exceeded then .
To extend this , Congressional approval is needed .
This means approval by both Republicans and Democrats .
But the Republican-Democrat gridlock has already started
(See Appendix A)

2.They would need to cut expenditure and raise taxes .
But special interests and conviction leads to conflict :
The Republicans do not want to raise taxes , or even abolish some tax-exemptions on big business .
The Democrats do not want to cut expenditure on Social Welfare .

Many on both sides are very sincere and convinced they are right .

The result will be Gridlock .

3.Perfect Financial Storm :
A USA default , combined with EU defaults , combined with effects of Japanese earthquakes , combined with Chinese slowdown and debt problems , reverberate and Domino back and forth .
The USA has done this before . The US Civil War and Prohibition are examples .

4.Completely unpredictable results will follow .
Social media like Facebook and Twitter will change forces into something strange . Hopefully rich as well .

5. Can something be done ?
Yes .
Two major problems can solve each other .
Financial and Environmental .
See http://andreswhy.blogspot.com "Financial Crisis 21 Jun 2011 : USA Default " Jun 2011 .

6. And for us small guys ?
Get your money out .
Grin and bear it .
Vote with your teeth .

Andre

Xxxxxxxxxxxxxxxxxxx

Appendix A
(Note the close approximations with Delian League around Siege of Syracuse)

From CNN 23 Jun 2011 :

Key Republican pulls out of debt ceiling talks, negotiations on verge of collapse
By: CNN's Deirdre Walsh and Dana Bash
Washington (CNN)-With only weeks to go before the country hits the debt ceiling, bipartisan negotiations were on the verge of collapsing as one of two Congressional Republicans walked away from the talks, and the other was unclear about future discussions.
House Majority Leader Eric Cantor withdrew from the negotiations Thursday, saying they had reached an impasse with Democrats over tax issues and it was time for President Obama to get involved to broker a deal that would pave the way for a vote to raise the debt ceiling this summer. Arizona Republican Senator Jon Kyl said that it would be difficult to continue negotiations with only one Republican at the table.

Talks planned for Thursday afternoon were scrapped after Vice President Joe Biden decided not to attend in light of Cantor’s announcement.
Cantor, who represented the House GOP in the discussions, said "there is not support in the House for a tax increase, and I don’t believe now is the time to raise taxes in light of our current economic situation. Regardless of the progress that has been made, the tax issue must be resolved before discussions can continue."
Cantor called on President Barack Obama to step in. “I believe it is time for the President to speak clearly and resolve the tax issue," he said.
An aide to Kyl told CNN that he also feels that the talks have gone as far as they can go with the players involved and the President now needs to personally get involved.
Rep. Chris Van Hollen, one of the House Democrats involved in the meetings, said there was no indication at yesterday’s session that the Republicans would stop participating.
Van Hollen said he learned the news as he was leaving a meeting with the President Thursday morning and was “disappointed.”
“They had been proceeding well although there is no doubt that there were some very difficult issues that needed to be decided,“ Van Hollen told reporters.
The bipartisan group, led by Vice President Biden, has been meeting for weeks behind closed doors to discuss various proposals to cut spending, from both discretionary programs and entitlement programs, such as Medicare. They have released very few details about areas of agreement, but Cantor said the group made significant progress agreeing to trillions in spending cuts, and noted “we have established a blueprint that could institute the fiscal reforms needed to start getting our fiscal house in order.” They had originally hoped to reach some sort of tentative agreement by July 1.
The group was working toward an agreement that would raise the debt ceiling by more than $2 trillion with an equivalent amount of spending cuts over the next ten years. Treasury Secretary Timothy Geithner said he expects the country to reach the debt ceiling by August 2, effectively halting the nation’s ability to borrow money and forcing the government into default on its obligations.
Multiple Democratic sources claim Cantor backed out of the talks because he doesn't want his fingerprints on an agreement that could face opposition from many House Republicans.
Several sources familiar with the bipartisan meeting on Wednesday said that it was incredibly tense and difficult.
Democrats involved in the negotiations have repeatedly said increasing tax revenues, from proposals such as ending subsidies for big oil companies, or companies producing ethanol, should be considered as part of the deal. Van Hollen said there was no justification for opposing those items “if you are serious about reducing the deficit.”
But the Democratic source—who would not speak on the record about the closed talks–said the Republicans in the negotiations have refused to accept any proposals that end any subsidies. "They're not willing to accept a dime of tax increases, we call it closing tax loopholes"
A Republican leadership, who also asked not to be identified, said it was the Democrats holding up progress because they refused to accept major changes to entitlement programs.
Senate Republican Leader Mitch McConnell went to the Senate floor and echoed Cantor’s message.
"Either someone on the other side has forgotten that there is strong bipartisan, bipartisan, opposition in Congress to raising taxes or someone is acting in bad faith. We’ve known for some time that tax hikes would be a poison pill to any deficit reduction proposal,” McConnell said.
As Republicans were stressing their position to keep taxes off the table, the Democratic source maintained the GOP was continuing to push for major cuts to programs that they knew Democrats would oppose.
"Republicans want to cut Medicare, Medicaid and education and want deep cuts because they’re unwilling to cut tax loopholes that benefit special interests,” the source said.
Van Hollen warned that those conservative Republicans who were opposing any deal to raise the debt limit were endangering the economy. “One thing that would take a fragile economy and break it would be for the United States to default on its obligations so nobody should be playing a game of political chicken with this issue.”

Xxxxxxxxxxxxxxxxxxxxx

Financial Crash on Aug 2 , 2011

Financial Crash on 2 Aug 2011
Andre Willers
23 Jun 2011

Synopsis :
Special interests will cause the USA to gridlock on extension of debt ceiling . The subsequent USA default will dwarf Greek default and cause global financial failures and lock-downs .
Dear Readers are advised to seriously consider exposure risks .
(Get out of Dodge City if you don't want to end up on boot hill.)

Discussion
1.The USA runs out of money on 2 Aug 2011 .
It has a legal debt ceiling (14.7 $Trillion) that will be exceeded then .
To extend this , Congressional approval is needed .
This means approval by both Republicans and Democrats .
But the Republican-Democrat gridlock has already started
(See Appendix A)

2.They would need to cut expenditure and raise taxes .
But special interests and conviction leads to conflict :
The Republicans do not want to raise taxes , or even abolish some tax-exemptions on big business .
The Democrats do not want to cut expenditure on Social Welfare .

Many on both sides are very sincere and convinced they are right .

The result will be Gridlock .

3.Perfect Financial Storm :
A USA default , combined with EU defaults , combined with effects of Japanese earthquakes , combined with Chinese slowdown and debt problems , reverberate and Domino back and forth .
The USA has done this before . The US Civil War and Prohibition are examples .

4.Completely unpredictable results will follow .
Social media like Facebook and Twitter will change forces into something strange . Hopefully rich as well .

5. Can something be done ?
Yes .
Two major problems can solve each other .
Financial and Environmental .
See http://andreswhy.blogspot.com "Financial Crisis 21 Jun 2011 : USA Default " Jun 2011 .

6. And for us small guys ?
Get your money out .
Grin and bear it .
Vote with your teeth .

Andre

Xxxxxxxxxxxxxxxxxxx

Appendix A
(Note the close approximations with Delian League around Siege of Syracuse)

From CNN 23 Jun 2011 :

Key Republican pulls out of debt ceiling talks, negotiations on verge of collapse
By: CNN's Deirdre Walsh and Dana Bash
Washington (CNN)-With only weeks to go before the country hits the debt ceiling, bipartisan negotiations were on the verge of collapsing as one of two Congressional Republicans walked away from the talks, and the other was unclear about future discussions.
House Majority Leader Eric Cantor withdrew from the negotiations Thursday, saying they had reached an impasse with Democrats over tax issues and it was time for President Obama to get involved to broker a deal that would pave the way for a vote to raise the debt ceiling this summer. Arizona Republican Senator Jon Kyl said that it would be difficult to continue negotiations with only one Republican at the table.

Talks planned for Thursday afternoon were scrapped after Vice President Joe Biden decided not to attend in light of Cantor’s announcement.
Cantor, who represented the House GOP in the discussions, said "there is not support in the House for a tax increase, and I don’t believe now is the time to raise taxes in light of our current economic situation. Regardless of the progress that has been made, the tax issue must be resolved before discussions can continue."
Cantor called on President Barack Obama to step in. “I believe it is time for the President to speak clearly and resolve the tax issue," he said.
An aide to Kyl told CNN that he also feels that the talks have gone as far as they can go with the players involved and the President now needs to personally get involved.
Rep. Chris Van Hollen, one of the House Democrats involved in the meetings, said there was no indication at yesterday’s session that the Republicans would stop participating.
Van Hollen said he learned the news as he was leaving a meeting with the President Thursday morning and was “disappointed.”
“They had been proceeding well although there is no doubt that there were some very difficult issues that needed to be decided,“ Van Hollen told reporters.
The bipartisan group, led by Vice President Biden, has been meeting for weeks behind closed doors to discuss various proposals to cut spending, from both discretionary programs and entitlement programs, such as Medicare. They have released very few details about areas of agreement, but Cantor said the group made significant progress agreeing to trillions in spending cuts, and noted “we have established a blueprint that could institute the fiscal reforms needed to start getting our fiscal house in order.” They had originally hoped to reach some sort of tentative agreement by July 1.
The group was working toward an agreement that would raise the debt ceiling by more than $2 trillion with an equivalent amount of spending cuts over the next ten years. Treasury Secretary Timothy Geithner said he expects the country to reach the debt ceiling by August 2, effectively halting the nation’s ability to borrow money and forcing the government into default on its obligations.
Multiple Democratic sources claim Cantor backed out of the talks because he doesn't want his fingerprints on an agreement that could face opposition from many House Republicans.
Several sources familiar with the bipartisan meeting on Wednesday said that it was incredibly tense and difficult.
Democrats involved in the negotiations have repeatedly said increasing tax revenues, from proposals such as ending subsidies for big oil companies, or companies producing ethanol, should be considered as part of the deal. Van Hollen said there was no justification for opposing those items “if you are serious about reducing the deficit.”
But the Democratic source—who would not speak on the record about the closed talks–said the Republicans in the negotiations have refused to accept any proposals that end any subsidies. "They're not willing to accept a dime of tax increases, we call it closing tax loopholes"
A Republican leadership, who also asked not to be identified, said it was the Democrats holding up progress because they refused to accept major changes to entitlement programs.
Senate Republican Leader Mitch McConnell went to the Senate floor and echoed Cantor’s message.
"Either someone on the other side has forgotten that there is strong bipartisan, bipartisan, opposition in Congress to raising taxes or someone is acting in bad faith. We’ve known for some time that tax hikes would be a poison pill to any deficit reduction proposal,” McConnell said.
As Republicans were stressing their position to keep taxes off the table, the Democratic source maintained the GOP was continuing to push for major cuts to programs that they knew Democrats would oppose.
"Republicans want to cut Medicare, Medicaid and education and want deep cuts because they’re unwilling to cut tax loopholes that benefit special interests,” the source said.
Van Hollen warned that those conservative Republicans who were opposing any deal to raise the debt limit were endangering the economy. “One thing that would take a fragile economy and break it would be for the United States to default on its obligations so nobody should be playing a game of political chicken with this issue.”

Xxxxxxxxxxxxxxxxxxxxx

Tuesday, June 21, 2011

Financial Crisis 21 Jun 2011 : USA Default

Financial Crisis 21 Jun 2011 : USA Default .
Andre Willers
21 Jun 2011

Synopsis :
The Financial System needs a Debt-Sink . A balancing Environmental Sink seems ideal .
Fixing the planet will equalize debts .

Discussion :
The Financial system has built up considerable debts to the Real System : things like the air you breathe , water you drink , food you eat .
See http://andreswhy.blogspot.com "Financial Crisis 10 Jun 2011" how this came about .

Forgiveness of Debts
This seems unlikely , given humans , and impossible given Nature .

Green Bonds .
Promises (Bonds) to fix the planet can be structured to give measurable , real yields .
Environmental Debts and Monetary Debts can be traded .
(Carbon credits are a small measure .)

In Essence :
Humans can trade their way out of the present threatening environmental extinction .
And get extremely rich in the process .

They even have all the sub-processes in place .

Will they do it ?

Watch the next thrilling episode of God's reality show "Earth : Survivor"

Andre

Financial

Financial Crisis 21 Jun 2011 : USA Default .
Andre Willers
21 Jun 2011

Synopsis :
The Financial System needs a Debt-Sink . A balancing Environmental Sink seems ideal .
Fixing the planet will equalize debts .

Discussion :
The Financial system has built up considerable debts to the Real System : things like the air you breathe , water you drink , food you eat .
See http://andreswhy.blogspot.com "Financial Crisis 10 Jun 2011" how this came about .

Forgiveness of Debts
This seems unlikely , given humans , and impossible given Nature .

Green Bonds .
Promises (Bonds) to fix the planet can be structured to give measurable , real yields .
Environmental Debts and Monetary Debts can be traded .
(Carbon credits are a small measure .)

In Essence :
Humans can trade their way out of the present threatening environmental extinction .
And get extremely rich in the process .

They even have all the sub-processes in place .

Will they do it ?

Watch the next thrilling episode of God's reality show "Earth : Survivor"

Andre

Saturday, June 18, 2011

Volcanic Ash Fall.

Volcanic Ash Fall.
Andre Willers
19 Jun 2011

Synopsis:
Light volcanic pumice fall is more deletrious than a heavy fall .

Discussion :
This is happening now in the Southern Hemisphere due to heavy pumice eruptions in Chile , Eritrea and other places .

The damage :
It is not ash , but pumice . A rock aerosol . The heavy bits fall out soon , but the very light pieces get carried over the whole hemisphere .

It is hygroscopic (lots of micropore structures) and agglutinates . Clogs up your lungs with cement . Which is why they just now grounded aircraft flights out of Southern African Airports (bad weather plus fine pumice ruins lifting surfaces and turbines )
Not good enough for a jet , but good enough for you to breathe .

Long-range power lines
These systems have fine-tuned it to the effect of wind on the cooling of electrical powerlines . (Well known heat = Current ^2 effect) .
This is widely used (a little thing ESKOM neglected to tell you)
A fine layer of pumice cemented by water insulates the powerline against wind-cooling effects . It can thus carry less current (effect is bottlenecked at about 15%) . So , expect power blackouts .

Asthma
Potentially lethal .
It is not known whether light volcanic pumice will trigger asthma attacks . It will definitely worsen existing attacks .
Filter masks are indicated .
(As usual , the medical establishment has done nothing)

Smoking :
This involves inhaling air through a filter . What will kill you first ?
As usual , the establishment (even the tobacco industry) has no idea , has not spent a cent on research .

Bah . Use a mask .

Or light up . There are some studies that indicate that enhanced CO levels has beneficial effects .
Humans have been through volcanic episodes many times , and have genetic baggage that will help .

Agriculture :
Micropores on leaf-structures get clogged up . Expect poor crops .
Especially on leafy things . Wines will get zapped from a volume point , but the vintages will be fantastic .(Vintages always get better because of feeding and choking)

Water Supply :
Systems that use carbon filters will clog up quickly .

Fishing :
This should get better . The element-rich pumice falls on ocean gyres , where they get concentrated and cause an explosion of plankton , feeding the fishes .

Rainfall :
This will increase . There are more nuclei for raindrops to condensate . The extra release of thermal energy will drive steeper gradients in atmospheric systems . Already happening .
This means faster winds , bigger storms , more floods .Not to be confused with Global warming .

Insects :
Expect explosions of insects and birds feeding on them .
But cockroaches and creeping insects will crash . The pumice abrades their abdomen as the try to slither .

Bacteria and Virii :
These are usually bottlenecked by a lack of trace elements . A light pumice fall makes these elements more available . Expect an explosion of these , but there are lots of negative feedback factors here .

Wash all food thoroughly . Pumice clogging up your intestines is a bit of no-no .
Especially if you abuse antiacids .(Your stomach acids are supposed to break up these nasties .)

Neurological effects
From an evolutionary viewpoint , a light pumice fall should make humans more antsy and irritable .There is a sufficient history of exposure to the stimulus , but I do not know the actual pathway .

Inhibition of panic
Panic is pro-survival for individual elements in localized disasters . This happens .

But in more general disasters , co-operation (ie inhibition of panic) is more beneficial
This happens , as well .

But why and how ?

A light volcanic fall seems to trigger an inhibition of panic . (Eg UK Iceland falls)
Nobody seems to have spent any time wondering why , so you will have to make do with my version of why .

Hibernation:
Very small concentrations of H2S (in the order of 20 ppm) (too small for humans to smell , but dogs will notice) trigger very deep energy shutdowns in the mitochondria and cells .This means smaller irritability and aggression .
See http://andreswhy.blogspot.com "Hibernation and Cryogenics" Oct 2008

I hesitate to release this , because it is an obvious subliminal pacifying agent .
But the future we are going into will require more than localized panic responses to survive .

Rather amusing :
The air-conditioning scrubbing out H2S is responsible for most of the panic financial crises .

Every hedge fund operator should have a little Stinky Spray (H2S at about 20 ppm) . Keeps the animals from devouring each other .

What can I say ?
Humans are having too much fun exploring the boundaries of their little environment .
God will provide .

But Earth is God's Reality Show . And it is called " No Survivors"

Andre

Dino burning bright!

Dino burning bright.
Andre Willers
17 Jun 2011

"Dino , Dino Burning Bright ! In the forests of the Night !" Apologies to Blake

I cannot get the image out of my mind of a Triceratops shrugging through leafage , radiating light from LED scales , with Laser horns lancing .

A Top Organism .
Look at those puzzling microgrooves on the horns . Waveguides .

They would have evolved biological lasers on the scales .
Can still be seen on chicken legs .

An ecology of hardy triceraptops sheltering fast , smallish dino's will overwhelm human ecologies . And once the larger ones get laser technology , humans can kiss their ass goodbye .

(Human weapon systems only work about 1/3 of the time , while theirs work 100% of the time .)

Isn't biotechnology wonderful !

Ever think that you might actually need those computer wargames ?

A real scaly thought .

Andre

Thursday, June 16, 2011

Algebra and Arithmetic

Algebra and Arithmetic
Andre Willers
16 Jun 2011

Synopsis :
Algebraic systems are a subset of Arithmetical systems . Statements true in algebra is always true in Arithmetic , but some statements true in Arithmetic can not be adduced in Algebra . A consequence of Godel's Theorem .

Discussion :
Of major consequence in the digital age . Digital systems like the brain (on-off neural systems) have characteristics that cannot even in theory be modeled by abstractions .
Or AI's . for that matter .

Why ?
Sweet and Simple :
Algebra's have meaning ceiling is at Octonions (8 dimensions)
http://www.google.co.za/search?aq=f&sourceid=chrome&ie=UTF-8&q=octonions+wiki
, while Arithmetical systems have a ceiling of 26 + 1 dimensions .
See http://en.wikipedia.org/wiki/Formula_for_primes

This has been discussed before .
An ArithI + ArithII Universe needs a minimum necessary sufficient number of primary dimensions of at least 27 .
Algebra's meaning ceiling is 8 dimensions , before it gets so complicated that humans give up in an algebraic sense . The patterns are too complicated . So , in typical human fashion , they think there are no more Arithmetical patterns . But they are lurking there , waiting to zap you !

You too can create a true statement in Arithmetic that is contradictory in Algebraic terms . Just use between 9 and 25 number dimensions .

The enormous gap is about (27 – 8 ) ! ~ 19 ! . A measure of human ignorance , not even taking into account Beth(1+) effects .

Now add dimensional rotations and spins (the two are not the same , though they are cousins )

The complexities are in the rotations and spins .

Feel stupid ?
Now you know how I feel all the time .

Andre

Algebra and Arithmetic

Algebra and Arithmetic
Andre Willers
16 Jun 2011

Synopsis :
Algebraic systems are a subset of Arithmetical systems . Statements true in algebra is always true in Arithmetic , but some statements true in Arithmetic can not be adduced in Algebra . A consequence of Godel's Theorem .

Discussion :
Of major consequence in the digital age . Digital systems like the brain (on-off neural systems) have characteristics that cannot even in theory be modeled by abstractions .
Or AI's . for that matter .

Why ?
Sweet and Simple :
Algebra's have meaning ceiling is at Octonions (8 dimensions)
http://www.google.co.za/search?aq=f&sourceid=chrome&ie=UTF-8&q=octonions+wiki
, while Arithmetical systems have a ceiling of 26 + 1 dimensions .
See http://en.wikipedia.org/wiki/Formula_for_primes

This has been discussed before .
An ArithI + ArithII Universe needs a minimum necessary sufficient number of primary dimensions of at least 27 .
Algebra's meaning ceiling is 8 dimensions , before it gets so complicated that humans give up in an algebraic sense . The patterns are too complicated . So , in typical human fashion , they think there are no more Arithmetical patterns . But they are lurking there , waiting to zap you !

You too can create a true statement in Arithmetic that is contradictory in Algebraic terms . Just use between 9 and 25 number dimensions .

The enormous gap is about (27 – 8 ) ! ~ 19 ! . A measure of human ignorance , not even taking into account Beth(1+) effects .

Now add dimensional rotations and spins (the two are not the same , though they are cousins )

The complexities are in the rotations and spins .

Feel stupid ?
Now you know how I feel all the time .

Andre

Quantum Energy Box.

Quantum Energy Box .
Andre Willers
16 Jun 2011

Synopsis :
Quantum Entanglement , Heisenberg's Uncertainty Principle and the Maxwell-Szilard Demon effects are combined to give a netto usable energy output .

Discussion :
See :
1."Uncertainty Entangled" NewScientist 30 Apr 2011 p28
2. "Demons ,Entropy and the quest for absolute zero" SciAm Mar 2011 p47 .

Combine the two as follows :
In a single box (Quantum Energy Box) (ie a reference framework) , place a high-temperature container with entangled particles , laced with generator conductor wires (Box Alice). This is connected to the cooling system (coilgun , etc) .(Box Bob)

Do the cooling as described .

As the uncertainty in the momentum (ie temperature) in the Box Bob is reduced , the uncertainty in the position of the Entangled-connected remainder in Box Alice is increased as per Heisenberg's Uncertainty Principle .

This means an effective transport of charges across the conductors in Box Alice , inducing electrical current . This can be utilized to drive the coil-gun and other processes in Box Bob .

There should be a netto energy effect , because of the Entanglement . (Roughly , the potential energy difference between Box Alice and Box Bob .)

This can be pulsed or even engineered into a steady state contraption .

Essentially , we are using macro-scale entanglement to get usable work out of a homogenous temperature mass .

Warning :
Be careful !
1.Momentum transfer might occur , depending on the specific physical design of the boxes . And it can be large . A useful spacedrive .
2.The energy surplus has not been calculated or done experimentally .
It will also be design-specific , but large induced currents should be inferred .
(Potential energy energy differences between Box Alice and Box Bob can be large.)
It can explode . Not a bomb , but energy release above design parameters.

And off you go .
Don't do anything I wouldn't do . And always wear a quantum condom .

Andre

Melatonin and Dinosaurs

Melatonin and Dinosaurs .
Andre Willers
14 Jun 2011

"Sleep that knits up the ravell'd sleave of care " Shakespeare

Synopsis :
Melatonin ended up in various evolutionary roles because of it's powerful , terminal antioxidant effect . Many neurotransmitters (especially NO classes) can be seen as free radicals . (See Appendix A)
Melatonin is Nature's Terminator . (See Appendix C)

Discussion:
A handy Terminator got roped into being the Enforcer for various feedback systems that had to be kept from repeating .

Examples :

1.Cancers (eg breast , prostate cancers)
Interruption of signaling molecules .

2.Circadian rhythms of the brain (sleep)
Dismantling runaway feedback systems before they corrupt long-term memory irreparably (sense of self) See Appendix C

3.Gut rhythms :
A separate system Melatonin excretion by various cells and bacteria .

4.Bile :
Funnily enough , a separate system . Why ?
Tied to the energy system and things like diabetes .

5.Mitochondria :
A sophisticated auto-governor on rates of activity relative to intra-cell position .
Really simple . Really cool . (Think a steam engine's governor) See Appendix B.

6.Skin
As expected , such a powerful terminal antioxidant will also be on the ramparts against foreign invaders (like in the gut)

7 Immune system
Basically a memory system , with potentially unlimited feedback .
Melatonin will terminate this as well , especially in localized , concentrated doses .
But note the correlation between blue-light and HIV .
Very high-intensity pulses of blue light (484 nanometers) or UV should disable the HIV virus .

Contradictions :
This is only seven usages .There are probably more . The same concentrations of melatonin cannot serve all .
Hence , melatonin receptors evolved to meter and control cellular responses .
As well as dopsin receptors in the visual systems .

Loss of UV Dopsins
About 100 MYA for mammals . Remnants (melanopsins) are still responsible for nervous system entrainment , but some biological adaptability (ie getting melatonin from diet) was lost .
It also means that humans are especially vulnerable to depression of melatonin production by light in the Blue Wavelengths (484 nanometers) . CFL and LED lights .
This means that you should only use blue lights if you want to be alert . The effect is very strong (about 100 times) .
Interesting , this should be able to be hyperreal . Diffraction patterns (as with insect , bird and reptile scales) could give blue-to UV light that the mammalian optical systems will interpret as hyperreal .And hyperactive .

Speculation :
Mammalian loss of these dopsins are thought to be the result of low level of light on the forest floor .
But what if the scaly animals had evolved to use Blue and UV as a weapon ?
It would have reduced melatonin production even in darkness .

Imagine huge , impregnable Dinosaur behemoths with a skin ecology of luminescent bacteria , the light diffracting from their scales into the blue and UV .
A magnificent sight !

Remnants :
Birds with brilliant UV plumages should have DNA of the lumenifages in suppressed state . Or you can do it the hard way from the skins of late-stage dinosaurs .

Light-flash Extinction :
An amusing thought . The extremely bright flashes of the meteors would have burned out the skin ecology of the dinosaurs , the subsequent darkness sending them into a terminal melatonin deep sleep . See FireFall .
This can be tested . Since melatonin is a terminal antioxidant , the breakdown products should be measurable even after 65 MY .

Chickens and flu's
The diseases can be seen as stripped-down versions of skin-symbiotes of the old dinosaurs . The worst thing you can do is subject them to UV Like in brooders . Self-assembly of old sequences will follow . A very old revenge .

What is a poor mammal to do ?
Because of the very many uses of melatonin , there is no single solution .
Sometimes you need more , sometimes less . The trick is to know when .
Also , the sources depend on light (especially blue light or UV) , gut , immune system , brain , pills(slow release or fast release) etc .

The basic principle is that it stops things dead . Slowly or quickly .
There is a tie-in with the sulfur mechanism that is responsible for the immobilization of all molecular cellular activity (concentrations of SO2 about 80 ppm)
Melatonin stops the SO2 blockage . At extremely low concentrations .
Look at the molecule .

This is a typical life-system . Blockages of blockages of blockages leading to a system with graduated responses .

Too little melatonin , and SO2 is not sufficiently blocked and the organism goes into stasis . Sleep .

Evolved into hibernation . The long light periods led to depletion of melatonin , leading to H2S hibernation . Neat .

SAD is a direct consequence . Too much melatonin leads to neurotransmitter depletion (especially serotonin)
A berserker has to generate high levels of neurotransmitters internally .

Take a pill !
As seen above , the system has many variants . Endo- and exo- just to start with . There are adjuvants (valerian is one) . Epigenetic variants are possible , but this system is so basic that I think adjuvants would give better results .

So , take a pill with timing and accompanying chemicals .
Each one should target a separate system .

Ageing
The SO2 system freezes things . The melatonin system unfreezes it .Pulsing the system enables living and repairing . Sleep with very carefully metered H2S will enable a very long life for those interested .

Who wants to live forever ?

Andre

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Appendix A

http://en.wikipedia.org/wiki/Melatonin
"Antioxidant
Besides its function as synchronizer of the biological clock, melatonin also exerts a powerful antioxidant activity. The discovery of melatonin as an antioxidant was made in 1993.[85] In many less complex life forms, this is its only known function.[86] Melatonin is an antioxidantthat can easily cross cell membranes and the blood-brain barrier.[6] Melatonin is a direct scavenger of OH, O2−, and NO.[87] Unlike other antioxidants, melatonin does not undergoredox cycling, the ability of a molecule to undergo reduction and oxidation repeatedly. Redox cycling may allow other antioxidants (such as vitamin C) to act as pro-oxidants, counterintuitively promoting free radical formation. Melatonin, on the other hand, once oxidized, cannot be reduced to its former state because it forms several stable end-products upon reacting with free radicals. Therefore, it has been referred to as a terminal (or suicidal) antioxidant.[88] "

Appendix B
" A potential mechanism is that melatonin promotes the recruitment of brown adipose tissue (BAT) as well as enhances its activity.[48] This effect would raise the basal metabolic rate by stimulating thermogenesis, heat generation through uncoupling oxidative phosphorylation in mitochondria."

Appendix C
http://en.wikipedia.org/wiki/Phase_response_curve#Melatonin_PRC

"PRC in neurons
Phase response curve analysis can be used to understand the intrinsic properties and oscillatory behavior of regular-spiking neurons.[8] The neuronal PRCs can be classified as being purely positive (PRC type I) or as having negative parts (PRC type II). Importantly, the PRC type exhibited by a neuron is indicative of its input–output function (excitability) as well as synchronization behavior: networks of PRC type II neurons can synchronize their activity via mutual excitatory connections, but those of PRC type I can not.[9]
Experimental estimation of PRC in living, regular-spiking neurons involves measuring the changes in inter-spike interval in response to a small perturbation, such as a transient pulse of current. Notably, the PRC of a neuron is not fixed but may change when firing frequency[10] or neuromodulatory state of the neuron[11] is changed."
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

Melatonin

Melatonin and Dinosaurs .
Andre Willers
14 Jun 2011

"Sleep that knits up the ravell'd sleave of care " Shakespeare

Synopsis :
Melatonin ended up in various evolutionary roles because of it's powerful , terminal antioxidant effect . Many neurotransmitters (especially NO classes) can be seen as free radicals . (See Appendix A)
Melatonin is Nature's Terminator . (See Appendix C)

Discussion:
A handy Terminator got roped into being the Enforcer for various feedback systems that had to be kept from repeating .

Examples :

1.Cancers (eg breast , prostate cancers)
Interruption of signaling molecules .

2.Circadian rhythms of the brain (sleep)
Dismantling runaway feedback systems before they corrupt long-term memory irreparably (sense of self) See Appendix C

3.Gut rhythms :
A separate system Melatonin excretion by various cells and bacteria .

4.Bile :
Funnily enough , a separate system . Why ?
Tied to the energy system and things like diabetes .

5.Mitochondria :
A sophisticated auto-governor on rates of activity relative to intra-cell position .
Really simple . Really cool . (Think a steam engine's governor) See Appendix B.

6.Skin
As expected , such a powerful terminal antioxidant will also be on the ramparts against foreign invaders (like in the gut)

7 Immune system
Basically a memory system , with potentially unlimited feedback .
Melatonin will terminate this as well , especially in localized , concentrated doses .
But note the correlation between blue-light and HIV .
Very high-intensity pulses of blue light (484 nanometers) or UV should disable the HIV virus .

Contradictions :
This is only seven usages .There are probably more . The same concentrations of melatonin cannot serve all .
Hence , melatonin receptors evolved to meter and control cellular responses .
As well as dopsin receptors in the visual systems .

Loss of UV Dopsins
About 100 MYA for mammals . Remnants (melanopsins) are still responsible for nervous system entrainment , but some biological adaptability (ie getting melatonin from diet) was lost .
It also means that humans are especially vulnerable to depression of melatonin production by light in the Blue Wavelengths (484 nanometers) . CFL and LED lights .
This means that you should only use blue lights if you want to be alert . The effect is very strong (about 100 times) .
Interesting , this should be able to be hyperreal . Diffraction patterns (as with insect , bird and reptile scales) could give blue-to UV light that the mammalian optical systems will interpret as hyperreal .And hyperactive .

Speculation :
Mammalian loss of these dopsins are thought to be the result of low level of light on the forest floor .
But what if the scaly animals had evolved to use Blue and UV as a weapon ?
It would have reduced melatonin production even in darkness .

Imagine huge , impregnable Dinosaur behemoths with a skin ecology of luminescent bacteria , the light diffracting from their scales into the blue and UV .
A magnificent sight !

Remnants :
Birds with brilliant UV plumages should have DNA of the lumenifages in suppressed state . Or you can do it the hard way from the skins of late-stage dinosaurs .

Light-flash Extinction :
An amusing thought . The extremely bright flashes of the meteors would have burned out the skin ecology of the dinosaurs , the subsequent darkness sending them into a terminal melatonin deep sleep . See FireFall .
This can be tested . Since melatonin is a terminal antioxidant , the breakdown products should be measurable even after 65 MY .

Chickens and flu's
The diseases can be seen as stripped-down versions of skin-symbiotes of the old dinosaurs . The worst thing you can do is subject them to UV Like in brooders . Self-assembly of old sequences will follow . A very old revenge .

What is a poor mammal to do ?
Because of the very many uses of melatonin , there is no single solution .
Sometimes you need more , sometimes less . The trick is to know when .
Also , the sources depend on light (especially blue light or UV) , gut , immune system , brain , pills(slow release or fast release) etc .

The basic principle is that it stops things dead . Slowly or quickly .
There is a tie-in with the sulfur mechanism that is responsible for the immobilization of all molecular cellular activity (concentrations of SO2 about 80 ppm)
Melatonin stops the SO2 blockage . At extremely low concentrations .
Look at the molecule .

This is a typical life-system . Blockages of blockages of blockages leading to a system with graduated responses .

Too little melatonin , and SO2 is not sufficiently blocked and the organism goes into stasis . Sleep .

Evolved into hibernation . The long light periods led to depletion of melatonin , leading to SO2 hibernation . Neat .

SAD is a direct consequence . Too much melatonin leads to neurotransmitter depletion (especially serotonin)
A berserker has to generate high levels of neurotransmitters internally .

Take a pill !
As seen above , the system has many variants . Endo- and exo- just to start with . There are adjuvants (valerian is one) . Epigenetic variants are possible , but this system is so basic that I think adjuvants would give better results .

So , take a pill with timing and accompanying chemicals .
Each one should target a separate system .

Ageing
The SO2 system freezes things . The melatonin system unfreezes it .Pulsing the system enables living and repairing . Sleep with very carefully metered SO2 will enable a very long life for those interested .

Who wants to live forever ?

Andre

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Appendix A

http://en.wikipedia.org/wiki/Melatonin
"Antioxidant
Besides its function as synchronizer of the biological clock, melatonin also exerts a powerful antioxidant activity. The discovery of melatonin as an antioxidant was made in 1993.[85] In many less complex life forms, this is its only known function.[86] Melatonin is an antioxidantthat can easily cross cell membranes and the blood-brain barrier.[6] Melatonin is a direct scavenger of OH, O2−, and NO.[87] Unlike other antioxidants, melatonin does not undergoredox cycling, the ability of a molecule to undergo reduction and oxidation repeatedly. Redox cycling may allow other antioxidants (such as vitamin C) to act as pro-oxidants, counterintuitively promoting free radical formation. Melatonin, on the other hand, once oxidized, cannot be reduced to its former state because it forms several stable end-products upon reacting with free radicals. Therefore, it has been referred to as a terminal (or suicidal) antioxidant.[88] "

Appendix B
" A potential mechanism is that melatonin promotes the recruitment of brown adipose tissue (BAT) as well as enhances its activity.[48] This effect would raise the basal metabolic rate by stimulating thermogenesis, heat generation through uncoupling oxidative phosphorylation in mitochondria."

Appendix C
http://en.wikipedia.org/wiki/Phase_response_curve#Melatonin_PRC

"PRC in neurons
Phase response curve analysis can be used to understand the intrinsic properties and oscillatory behavior of regular-spiking neurons.[8] The neuronal PRCs can be classified as being purely positive (PRC type I) or as having negative parts (PRC type II). Importantly, the PRC type exhibited by a neuron is indicative of its input–output function (excitability) as well as synchronization behavior: networks of PRC type II neurons can synchronize their activity via mutual excitatory connections, but those of PRC type I can not.[9]
Experimental estimation of PRC in living, regular-spiking neurons involves measuring the changes in inter-spike interval in response to a small perturbation, such as a transient pulse of current. Notably, the PRC of a neuron is not fixed but may change when firing frequency[10] or neuromodulatory state of the neuron[11] is changed."
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

Melatonin and Dinosaurs

Melatonin and Dinosaurs .
Andre Willers
14 Jun 2011

"Sleep that knits up the ravell'd sleave of care " Shakespeare

Synopsis :
Melatonin ended up in various evolutionary roles because of it's powerful , terminal antioxidant effect . Many neurotransmitters (especially NO classes) can be seen as free radicals . (See Appendix A)
Melatonin is Nature's Terminator . (See Appendix C)

Discussion:
A handy Terminator got roped into being the Enforcer for various feedback systems that had to be kept from repeating .

Examples :

1.Cancers (eg breast , prostate cancers)
Interruption of signaling molecules .

2.Circadian rhythms of the brain (sleep)
Dismantling runaway feedback systems before they corrupt long-term memory irreparably (sense of self) See Appendix C

3.Gut rhythms :
A separate system Melatonin excretion by various cells and bacteria .

4.Bile :
Funnily enough , a separate system . Why ?
Tied to the energy system and things like diabetes .

5.Mitochondria :
A sophisticated auto-governor on rates of activity relative to intra-cell position .
Really simple . Really cool . (Think a steam engine's governor) See Appendix B.

6.Skin
As expected , such a powerful terminal antioxidant will also be on the ramparts against foreign invaders (like in the gut)

7 Immune system
Basically a memory system , with potentially unlimited feedback .
Melatonin will terminate this as well , especially in localized , concentrated doses .
But note the correlation between blue-light and HIV .
Very high-intensity pulses of blue light (484 nanometers) or UV should disable the HIV virus .

Contradictions :
This is only seven usages .There are probably more . The same concentrations of melatonin cannot serve all .
Hence , melatonin receptors evolved to meter and control cellular responses .
As well as dopsin receptors in the visual systems .

Loss of UV Dopsins
About 100 MYA for mammals . Remnants (melanopsins) are still responsible for nervous system entrainment , but some biological adaptability (ie getting melatonin from diet) was lost .
It also means that humans are especially vulnerable to depression of melatonin production by light in the Blue Wavelengths (484 nanometers) . CFL and LED lights .
This means that you should only use blue lights if you want to be alert . The effect is very strong (about 100 times) .
Interesting , this should be able to be hyperreal . Diffraction patterns (as with insect , bird and reptile scales) could give blue-to UV light that the mammalian optical systems will interpret as hyperreal .And hyperactive .

Speculation :
Mammalian loss of these dopsins are thought to be the result of low level of light on the forest floor .
But what if the scaly animals had evolved to use Blue and UV as a weapon ?
It would have reduced melatonin production even in darkness .

Imagine huge , impregnable Dinosaur behemoths with a skin ecology of luminescent bacteria , the light diffracting from their scales into the blue and UV .
A magnificent sight !

Remnants :
Birds with brilliant UV plumages should have DNA of the lumenifages in suppressed state . Or you can do it the hard way from the skins of late-stage dinosaurs .

Light-flash Extinction :
An amusing thought . The extremely bright flashes of the meteors would have burned out the skin ecology of the dinosaurs , the subsequent darkness sending them into a terminal melatonin deep sleep . See FireFall .
This can be tested . Since melatonin is a terminal antioxidant , the breakdown products should be measurable even after 65 MY .

Chickens and flu's
The diseases can be seen as stripped-down versions of skin-symbiotes of the old dinosaurs . The worst thing you can do is subject them to UV Like in brooders . Self-assembly of old sequences will follow . A very old revenge .

What is a poor mammal to do ?
Because of the very many uses of melatonin , there is no single solution .
Sometimes you need more , sometimes less . The trick is to know when .
Also , the sources depend on light (especially blue light or UV) , gut , immune system , brain , pills(slow release or fast release) etc .

The basic principle is that it stops things dead . Slowly or quickly .
There is a tie-in with the sulfur mechanism that is responsible for the immobilization of all molecular cellular activity (concentrations of SO2 about 80 ppm)
Melatonin stops the SO2 blockage . At extremely low concentrations .
Look at the molecule .

This is a typical life-system . Blockages of blockages of blockages leading to a system with graduated responses .

Too little melatonin , and SO2 is not sufficiently blocked and the organism goes into stasis . Sleep .

Evolved into hibernation . The long light periods led to depletion of melatonin , leading to SO2 hibernation . Neat .

SAD is a direct consequence . Too much melatonin leads to neurotransmitter depletion (especially serotonin)
A berserker has to generate high levels of neurotransmitters internally .

Take a pill !
As seen above , the system has many variants . Endo- and exo- just to start with . There are adjuvants (valerian is one) . Epigenetic variants are possible , but this system is so basic that I think adjuvants would give better results .

So , take a pill with timing and accompanying chemicals .
Each one should target a separate system .

Ageing
The SO2 system freezes things . The melatonin system unfreezes it .Pulsing the system enables living and repairing . Sleep with very carefully metered SO2 will enable a very long life for those interested .

Who wants to live forever ?

Andre

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Appendix A

http://en.wikipedia.org/wiki/Melatonin
"Antioxidant
Besides its function as synchronizer of the biological clock, melatonin also exerts a powerful antioxidant activity. The discovery of melatonin as an antioxidant was made in 1993.[85] In many less complex life forms, this is its only known function.[86] Melatonin is an antioxidantthat can easily cross cell membranes and the blood-brain barrier.[6] Melatonin is a direct scavenger of OH, O2−, and NO.[87] Unlike other antioxidants, melatonin does not undergoredox cycling, the ability of a molecule to undergo reduction and oxidation repeatedly. Redox cycling may allow other antioxidants (such as vitamin C) to act as pro-oxidants, counterintuitively promoting free radical formation. Melatonin, on the other hand, once oxidized, cannot be reduced to its former state because it forms several stable end-products upon reacting with free radicals. Therefore, it has been referred to as a terminal (or suicidal) antioxidant.[88] "

Appendix B
" A potential mechanism is that melatonin promotes the recruitment of brown adipose tissue (BAT) as well as enhances its activity.[48] This effect would raise the basal metabolic rate by stimulating thermogenesis, heat generation through uncoupling oxidative phosphorylation in mitochondria."

Appendix C
http://en.wikipedia.org/wiki/Phase_response_curve#Melatonin_PRC

"PRC in neurons
Phase response curve analysis can be used to understand the intrinsic properties and oscillatory behavior of regular-spiking neurons.[8] The neuronal PRCs can be classified as being purely positive (PRC type I) or as having negative parts (PRC type II). Importantly, the PRC type exhibited by a neuron is indicative of its input–output function (excitability) as well as synchronization behavior: networks of PRC type II neurons can synchronize their activity via mutual excitatory connections, but those of PRC type I can not.[9]
Experimental estimation of PRC in living, regular-spiking neurons involves measuring the changes in inter-spike interval in response to a small perturbation, such as a transient pulse of current. Notably, the PRC of a neuron is not fixed but may change when firing frequency[10] or neuromodulatory state of the neuron[11] is changed."
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

Saturday, June 11, 2011

Why aren't plants self-sufficient ?

Why aren't plants self-sufficient ?
Andre Willers
11 Jun 2011

Synopsis :
Efficiency . Certain functions like nitrogen concentration , diurnal energy generation and pollination were outsourced to more efficient intermediators like Your Motile Animals . (Like you and me)

Discussion :
Orbital-locked extrasolar planets will have some very aggressive plants , that have never even considered vegetarianism .

Root on the trot .

More mundane , nitrogen fixation has very old genetic roots .
See "NewScientist 7 May 2011 p 8 Food Crops to fix fertilizer from the air"
Genetical links with fungi .
In other words , all plants had this capability , but it was suppressed .
Note : not lost . Genetic engineering techniques are reactivating some of these old pathways .

The question is why they suppressed them in the first place .
Is it such a good idea to reactivate them ?

Remember , Humans are one of the animals that evolved as a result of the evolutionary interest plants have in having motiles in a relatively low and fluctuating energy environment .

Control mechanisms :
As previously discussed , Non-Angiosperm systems forms a Reserve in Gaia . Major fluctuations in fungi-spores will lead to Bad Things unless you know exactly what you are doing .

Terminator genes .
Much as I hate to admit it , nitrogen fixation genes have to be controlled . If not , the tipping point will move against motiles (humans , animals ,insects ,etc)

These are not conscious systems . If you make a feedback mistake , you are extinct .
(Plants have a small sense humor.)

Why the suppression of nitrogen-fixation genes ?
Evolutionary reasons .
1.Suppose all plants had the genes .(Like they had)
2.They die
3.Nitrogen , energy rich molecules drift downstream , to fuel competitors .
4.Motiles will use less energy , plus a huge bonus in reproductions stakes .
5.There is a balance . The Dear Reader can calculate it . If you are on the wrong side of it , you will not fare well .
Even on the short term .

Immobile motiles are severely penalized .
Usually extinction .
This is built in at a genetic level .

Music gives an illusion of moving at a genetic level (compression waves)
A slow cheat .

Amusing :
Problems with lack of gravity in spaceflight can be countered by heavy soundwaves . Local acceleration waves , which can be biased to give a pseudo-gravity at cellular level .
Basically heavy rock , coming or going .
Even terrestrial athlete training . The micro-tubules are very sensitive .

No wonder plants like music .
It is one of the few ways they can travel and experience new things .
But they are considerably slower .
From their viewpoint , we all have unbearably squeaky voices .
Lower the speed of transmission and frequency .
Trivial .
Compensate .

You might even convince them to increase yields , or kill pesky pests .
Intestinal flora ?
A conversation with your gut should fall under the Protection of Information Act (unless your spouse has court order , forcing the bacteria to divulge their recent activities . The mind boggles)

I would not mind a conversation with Garlic .
Not long on the meaning of Life , but trenchant on the meaning of death .

Plants like space travel .
Halfway to Jupiter you will have a plant pop up and ask "Are we there yet ?"
That is why they cultivated motiles in the first place . Slow does not mean stupid .
And it is a distributed identity .

Plant-Human Interaction :
SETI
Talk to your gut as if it is a non-human intelligence with slow communication problems .
Drum "shave and haircut " on your stomach and the bacteria will understand
Try it .
It actually works ,

Belief is immaterial

Andre

Thursday, June 09, 2011

Financial Crisis 10 Jun 2011 : Debt .

Financial Crisis 10 Jun 2011 : Debt
Andre Willers
10 Jun 2011

Synopsis :
Debt is a mass societal phenomenon . Small-scale interpersonal obligations are handled by a completely separate system , usually called "Favours" , or "You owe me one"

Discussion :
The system is driven by efficiencies .

I will discuss the end-state applicable to our present civilization .
Less than 10% of the workforce is needed to produce all the goods for the civilization .This means that 90% of the workforce cannot perform a function that enables them to have an income to afford the products of the productive 10% .
But they need these products to live . They can only then produce promises to pay .

Debt .

This sums up the state of the Planet Earth about Jun 2011 .

Globalization :
Production enabling an income to buy goods have been cleverly outsourced to the lowest-cost 10% of the world's population (China) . They are paid in monetary units subsidized by their own savings .

Regions like the USA now have little real income , but a large military presence .

You can see where this goes .

Any specialization produces debt . Run-up into the Singularity exacerbates debt .

Debt forgiveness
About the only way out for this half-baked lot .

This won't happen .
On Aug 2 , 2011 , the USA systems will lock up , and the system will go into meltdown as money dries up .

All for the best of possible motives , of course .

Andre