Professional and Ostrum .
Andre Willers
25 Nov 2012
Synopsis:
We analyse demands on the Professional’s attention using Ostrum Metarules .
Discussion :
The eight actual metarules are in Appendix I .A below . Humans do not have the capability of grasping or seeing them all at once , so we will have to do them item-by-item .
Can humans actually “grow”” to encompass all the 27 Rules necessary and Sufficient to describe the Universes ? . Not difficult at all . They then create new Universes , but make them more interesting by pinching boundaries .
1.The Common Resource is all the Information Demanding systems wanting a portion of the Professional’s attention .
2.Tragedy of the Commons variant .
Exploitation of the free information to the max , with attempts to inhibit certain channels . Doomed to failure . The resource is effectively infinite , because (A + ~A < Universum) . No constraint is possible in the long term .
Short term constraints are possible .
3.Network Theory :
“Small worlds” networks are the general human networks of pushing information . This simply means that most information is sent and handled by “close” nexi , but there are long-range neurons that carry information to other nexi (or mirror networks) .
4.First Pass on Overstimulation of Information :
Simply pass it on to onto the subsidiary networks , except for Amygdala Interrupts . (See Appendix II)
5. Second pass :
Correlations have been made at very low levels . Rethinks .
6. Third and n’th passes :
You get the drift . The system refines itself through feedback processes .
7.Predictive rewards :
This is where we get to the nitty-gritty of Ostrum Systems .
Any farming system , agricultural or not, foregoes present reward for future benefits . You have to get Oabout eight things right to make a living .
Thoe domain of dopamine-systems . Once you enter it , you cannot leave it .
8. Humans farm the noosphere the same as they farm the land . But that same pesky 8’th term disturbs things . The relationship to higher Beth(x) beings . The disturbance is built-in and unavoidable.
9. Osrtum managed to get 7/8 system rules independent of the observer . A significant accomplishment .
What does this mean ? Small scale systems can be predicted and manipulated .
10. This means you !
A Small thing , but my own .
Andre
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Appendix I
The only Game in town .
The Ostrum Game
Andre Willers
30 Oct 2011
“One Game shall bind them all .” , ( with apologies to Tolkien)
“This time , we know for sure the grass is greener somewhere”
“A Revolution , any Revolution.”
Synopsis :
A Game for Grown-ups .
The Eight Ostrum Design Principles are Meta-rules that generate self-consistent sets of rules that encompasses competition , co-operation , catastrophe , hierarchies and other systems undreamt of , all between discrete , interacting , self-organising systems .
Your avatar can go from SecondLife to Simworld , to War Worlds , to any desired locale .
Reality becomes a subset .
Discussion :
1.An incredible amount of money can be made .While money still has some meaning .
Without too much work . See Para 8 in Appendix A
Each Game Company is a base nested institution .
They bind easily together , releasing a lot of energy and money .
Explosive Feedback Synergism .
A run-up to the Singularity .
2.Feedback between Games and Reality :
The Meta-rules make no differentiation between Game-characters and Real-characters .
Indeed , many Real-characters have been spun into Game-characters , and vice-versa .
Think Sherlock Holmes , MacGyver , Gauss , young Werther etc
See “mirror-neuron networks” , any soap opera , etc .
Real-life problems get treated the same way as Game problems . The more diverse and sophisticated the Game interactions become , the more effect on any real or Game system .
Eventually , they become undistinguishable as technology progresses .
3.The Grass is provably greener somewhere .
Long known as a wishful thinking fallacy , until Ostrum published the Design Principles in 1990 .
This was the trigger event of under-the-surface knowledge about Ostrum Rules building up .
Suddenly , it became possible .
A Phase-change in the noosphere occurred .
It meant that a Disaster of the Commons or an Empire was not inevitable . Grandchildren could survive .
WE CAN MAKE THE GRASS GREENER , EVEN IF WE HAVE TO PAINT IT ONE BLADE AT A TIME .
Enormous tensions began surfacing . These effects are still playing out now .
A really , really major Hysterical Focus started forming , and is still intensifying .
Now , are you surprised that 1990 was the year of huge revolutions , when the USSR collapsed ?
The Ostrum Game beat the Ring of Power .
And you have not seen anything yet .
The pace of Revolutions is intensifying .
A good thing , if Homo wishes to escape extinction .
4.Automating Ostrum Rules :
They might be Meta-rules , but they are still rules .
We can certainly write programs that can serve to guide past most of the pitfalls and suggest alternatives .
5.Multicellular Bodies as Commons :
We can certainly analyze bodies in terms of Commons . The Dear Reader will find many interesting things if he does that .
Note the emphasis on communication .
Talk to your body . Aloud . And listen in the silences in between .
Create a virtual body and note the interactions .
Use the Ostrum Design principles .
6.Singularity :
It is immediately obvious that humans are then not limited to Real biochemical definitions of personality . The emphasis on communication means that personalities are distributed across Real and Game spaces . The Game space personality segments are only limited by internal non-contradictory rules . That can be done via Ostrum Design principles .
Not exactly instantaneous , but I can intuit that the time can be calculated . It would be less than real time .
The putative developing system would have ethical constraints on abandoning Real-part personalities under Ostrum Rules .
Told you it would be kindler , gentler .
7.Phase Change :
The system has already undergone an irrevocable phase change in 1990 .
You can fast-forward the rest .
8.Did Ostrum know what she was unleashing ?
The Revolutionary aspects , nearly certainly .
In her quiet way , she is one of the greatest Revolutionaries in Homo Sapiens history . Worthy of being called a Matriarch .
The Singularity aspect is more uncertain . She certainly knew that she unleashed major fairness , but the phase-change in the Noosphere I do not know .
Still , a tour-de-force .
How do feel like being a pet of your avatar ?
Andre .
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Appendix A
See http://en.wikipedia.org/wiki/Elinor_Ostrom
To quote from Wiki : (comments in brackets are my own ).
“ Ostrom identifies eight "design principles" of stable local common pool resource management:[10]
1. Clearly defined boundaries (effective exclusion of external un-entitled parties;
2. Rules regarding the appropriation and provision of common resources that are adapted to local conditions; (Equal sharing of debts and rewards)
3. Collective-choice arrangements that allow most resource appropriators to participate in the decision-making process; (Consensus decisions-no leveraged hierarchies)
4. Effective monitoring by monitors who are part of or accountable to the appropriators; (Policing)
5. A scale of graduated sanctions for resource appropriators who violate community rules; (Opportunity to learn from mistakes )
6. Mechanisms of conflict resolution that are cheap and of easy access; (Fair and Fast Justice . See how Inquisitorial Justice systems like Chinese , French or Sharia does it.)
7. Self-determination of the community recognized by higher-level authorities; (Autonomy within clearly defined levels . Something like a Federation.)
8. In the case of larger common-pool resources,organization in the form of multiple layers of nested enterprises, with small local CPRs at the base level. (Clear and quick relations with others. A potential sticky point with states.)
Governing the Commons: The Evolution of Institutions for Collective Action Ostrom, Elinor, Cambridge University Press, 1990 “
The most important book in the Twentieth Century .
Try to read it .
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Sunday, November 25, 2012
Friday, November 23, 2012
Saving the Rhino
Saving the Rhino
Andre Willers
23 Nov 2012
Synopsis:
Dopamine-shortage Syndromes (like Wandering Legs Syndrome ) can be alleviated by horns , especially Rhino horns . But better relief can be gotten by drugs such as Pexola (refer Viagra and impotence).
Discussion :
1.The Restless Legs Syndrome (RLS).
See Appendix II
Restless Legs Syndrome is an extremely stressful syndrome partly triggered by Wandering Feet Syndrome (peripheral neuropathy) . The two are often confused . The stress causes a feedback effect of worsening tendencies to stress-related diseases like cancer . This relates diabetes and acrylamide damage to deeper dopamine-related diseases in the brain (eg Parkinson’s , addiction , RLS , etc)
See Appendix I
2.A simple management :
Pexola (trade name for Pramipexole)
The brakes on the dopamine feedback systems . Receptor site D2 applies .
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http://de.wikipedia.org/wiki/Pramipexol
Pramipexole is a dopamine agonist with high selectivity and specificity of D 2/3 - dopamine receptors . In the early stages of Parkinson's disease Pramipexole stimulates the presynaptic D2 autoreceptors, inhibiting the excessive dopamine synthesis and release. In the late stage reinforces the pramipexole-ending dopamine synthesis through stimulation and modulation of postsynaptic D 2 -. And D 3 receptors [5]
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3.Humans with large genetic components of Denisovan (South Asia and Pacific via Formosa) and Neanderthal (North-west Europe) genes will have neurological problems because of fast-twitch muscle demands . The fast-twitch muscles build up action potential chemicals , which in turn randomly activate while waiting for orders . This reverberates in the central brain as an anxiety and frantic efforts to justify the muscle activity . The brain is out of the decision loop .
Over the long term , this gives rise to highly undesirable makework activity by the brain (ie tremors in Parkinson’s) .
At the cellular level even more undesirable activities occur . See Appendix C at the end “How to run faster” . CO2 disposal and glucose-demand are not regulated properly .
The mitochondria do not rotate at an even speed . Like in a diesel-electric setup , it is most efficient if the mitochondria generates ATP at a steady rate .
4.CO2 concentrations .
As previously noted , it seems that humans had a genetical bottleneck episode (most likely Toba circa 72 000 years ago) when the CO2 levels where higher after most of the vegetation was burnt or decomposing . Plus some very old gene-adaptations from 65 MYA of the KT catastrophe activating .
Plus an H2S component of about 1/9 to 1/3 of 80 ppm causing activation of hind-brain (reptilian) functions inhibiting higher brain functions and promoting fast-twitch muscles .
5.What does all this mean ?
5.1 Athletes:
Sprinters and fast-twitch specialists will perform better if they have higher CO2 levels and an imperceptible whiff of about 15 ppm of H2S . About four slow pushups without breathing will also enable reserves held by amygdala mechanisms . See Appendix D
5.2 Diabetics and Parkinsonian’s
The same for them .
6.The rhino
Why bother with rhino-horn if a better alternative is available . The Viagra solution .
7.An interesting aside :
Very low concentrations of H2S as a trigger to hyper fertility .
See Appendix E .
Things grow like mad near volcano’s . Always supposed to be fertility of the soil . But more likely to be suppression of more primitive bacterial competitors due to H2S hibernation effect . Finally , near the mid-Atlantic fumaroles close to a Scottish isle is hopped to the human genepool in 1704 AD . Or was it simply a reactivation of an older gene ? However , the gene seems to be burning out , partly due to human burial practices . Large scale cremation always led to higher fertility rates .
A childless couple burning to have a child will be much more likely to conceive if she breathes a 9% higher CO2 concentration , as well as about 15 ppm of H2S after 4 trembling pushups .
Make of it what you wish .
Rhino’s don’t do Pushups .
It is up to you to do it for them .
It is not a dilemma .
Unilemmically yours
Andre
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Appendix I
Rhino Horns and Diabetes .
Andre Willers
11 Apr 2012.
Synopsis :
Rhino horn makes people feel better because it decreases “wandering feet “ of diabetes.
Better substitutes are available .
Discussion :
Fast twitch muscles require fast service by the nervous system . If this does not occur , local “pacemakers” step in . One locus is the heart (the heart pacemaker) . Another is situated at the base of the spine , where the long nerves connect to the spinal cord .
This well known as the source of phantom pain signals . (Lower back pain) .
But if the signals from the brain does not get to the muscles , the pacemaker activates . Muscles in the legs are stimulated , giving rise to a feeling of unease . These signals bypass the roadblocks which were due to the damage to transport mechanism of the nerves .
Certain states in the nerve is quantum forbidden , so the energy skips on . The signal travels faster .This enabled fast-twitch muscles to function and contract at frequencies not normal for nerves , but if it is not coordinated . a very uncomfortable feeling results in sleeplessness .
Rhino horn contains some chemicals that involve nerve transmission speeds .
http://www.jbc.org/content/128/1/181.full.pdf
Metabolic Sulphur , tyrosine(9%) and tryptophane (9%) seems to be an acceptable substitute .
Or exercise the fast twitch muscles in the legs by doing snap-kicks .
People susceptible to this would be descendants of Denisovans (eg Vietnamese) or Neanderthals (North-Western Europe) .
Note that the main fast-twitch muscle artists (lions ,etc) all eat hair and horn , which humans don’t .
Interesting asides:
1.Are human fast-twitch muscle artists like kung-fu experts more susceptible to diabetes ? The evidence seems to indicate it .
2. Can the rhino be saved like with Viagra ? Not unless the medical establishment acknowledges that there is a real effect , and offers a better alternative . Interestingly , the Vietnamese only started suffering from wandering feet after they got rich and stopped eating keratine food .
3.If keratine enables fast twitch nervous impulses , eating rhino-horn will give you a heart attack if you take beta-blockers as well .
Cow’s feet or chicken feet , anybody ?
Andre
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Appendix II
Juggling and Parkinson’s Disease II
Andre Willers
3 Nov 2012
Synopsis :
Juggling increases brain white-matter (experimental) . The reward mechanism is dopamine . The inhibition of (inhibition of dopamine) is partly governed by ethylene . Plant-whisperers get more organically active ethylene . The two combine in a synergistic way .
Discussion :
Some people have wondered what the connection between juggling and plant whispering is . The connection is dopamine via ethylene and it’s bio-active compounds . Plant-whispering alone will inhibit the inhibition of dopamine-forming , but it is enhanced by some orders of magnitude if juggling is included . Synergism .
You will need the building –blocks of the nervous system like omega-3 oils (flax seed oil) and cod liver oil .
Will a whiff of ethylene help (ie like ripe banana peels) ?
I have no idea . (Personally , I would rather be caught sniffing banana peels than whispering to plants . But maybe it’s just me .)
At least the juggling is recognized .
Juggling and Mirror-neurons
The essence of it .
Juggling forces the growth of new mirror-neuron networks . This can be enhanced by personalizing the juggling objects , with smiles on them . A mature network will recognize them (characters from well-known soapies , etc) . This works at even a single neuron level .
You can make it interactive . Something like WII . I don’t think purely virtual will work . There has to be muscle interaction .
By gad , a new toy ! Juggle your way into the soapies . Lots of money to be made from the old wrinklies .
Sports :
If you star player seems to have hit a plateau , grow some new mirror-neurons by juggling .
Business :
The new executive toy . A multi-tasking trainer that actually works .
Sex:
Your pleasure centres can juggle things in ways you have not even thought about .
Money :
New mirror-neurons gives you a new perspective .
Old Age:
Boredom is a killer . It is not that there are no new experiences , it is that any experience is translated along old neural paths . So they see only the ho-hum similarities , but not the new experience . For that you need some new pathways . Hence juggling .
Immune system :
The immune system gets bored as well (it is evolutionary programmed in.) It needs both muscle and brain new chemicals to activate new switches in the DNA-Epigenetic system . Unused systems gets apoptized via the epigenetic system .
Music :
Music to juggle by . I do not know of any , but doubtlessly there will soon be some .
What to do ?
1.Start juggling .
2.Take brain food chemicals like Omega fats .
3.Get a plant to whisper to . Your Confessor plant . Make sure it has no microphone in it .
Dopamaniacally yours
Andre
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Appendix I
http://www.findingdulcinea.com/news/science/2009/oct/Juggling-Shown-to-Change-Wiring-of-the-Brain.html
Juggling Shown to Change Wiring of the Brain
October 14, 2009 07:00 AM
by Denis Cummings
An Oxford University study has found that practicing a task such as juggling can alter the structure of the brain, indicating that the plasticity of the brain is greater than previously believed.
Juggling Increases White Matter
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Researchers tested the brains of 48 volunteers, half of whom were given weekly juggling lessons for six weeks. At the end of that period, their brains were tested again. Those who had juggled—regardless of whether they had become good jugglers—had a 5 percent increase in their brains’ white matter, the nerve strands that connect different parts of the brain. Those who hadn’t juggled had little change.
Previous studies have found that juggling and other mind tasks—such as cabbies memorizing the streets of London—increased the amount of grey matter, the portion of the brain that contains neurons. This is the first study to find that white matter is affected.
Lead researcher Dr. Heidi Johansen-Berg said that the research shows “the structure of the brain is ripe for change.” It raises hope that scientists can design treatments to improve brain function for those with dementia or neurodegenerative diseases such as multiple sclerosis, Alzheimer’s and Parkinson’s.
“Knowing that pathways in the brain can be enhanced may be significant in the long run in coming up with new treatments for neurological diseases, such as multiple sclerosis, where these pathways become degraded,” said Johansen-Berg.
The study, “Training induces changes in white-matter architecture,” is published in Nature Neuroscience.
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Appendix II
How to juggle .Note the “Aha!” hurdle . A general empowerment mechanism .
http://www.yoyoguy.com/info/ball/index2.html
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Appendix III
Gravity independent . Note mesons .
http://en.wikipedia.org/wiki/Juggling
Space
Juggling has been performed in space despite the fact that the micro-gravity environment of orbit deprives the juggled objects of the essential ability to fall. This is accomplished through 'two-person' juggling passing multiple objects between them. Juggling in space was demonstrated by Greg Chamitoff andRichard Garriott[citation needed] while Garriott was visiting the International Space Station as aSpaceflight Participant in October 2008. Their juggling of objects while in orbit was featured in 'Apogee of Fear', the first science fiction movie made in space by Garriott and 'Zero-G Magic', a magic show also recorded in space by Chamitoff and Garriott at that time.
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Appendix IV
A commercial application of ethylene inhibition of growth hormones , including dopamine .
http://www.ncbi.nlm.nih.gov/pubmed/21402183
Dopamine-assisted immobilization of poly(ethylene imine) based polymers for control of cell-surface interactions.
Tsai WB, Chien CY, Thissen H, Lai JY.
Source
Department of Chemical Engineering, National Taiwan University, 1 Roosevelt Road, Section 4, Taipei 106, Taiwan. weibortsai@ntu.edu.tw
Abstract
Non-fouling coatings play a critical role in many biomedical applications, such as diagnostic assay materials, biosensors, blood contacting devices and other implants. In the present work we have developed a facile, one step deposition method based on dopamine polymerization for preparation of non-fouling and biotinylated surfaces for biomedical applications. Poly(ethylene imine)-graft-poly(ethylene glycol) co-polymer (PEI-g-PEG) was mixed with an alkaline dopamine solution and then deposited onto different substrates. The dopamine coatings formed by this method were characterized by X-ray photoelectron spectroscopy (XPS), and the results indicated successful deposition of PEG. The resultant dopamine coatings formed on tissue culture polystyrene by this method revealed successful deposition of PEG, as shown by XPS. PEI-g-PEG/dopamine deposition for 2h inhibited the adsorption of serum proteins and the attachment of fibroblasts, suggesting that PEG molecules were immobilized in a sufficient density on the surface of the coating. Furthermore, co-deposition of PEI-g-PEG and PEI-g-biotin in alkaline dopamine solutions provided a cell-resisting background surface, at the same time providing accessible biotin molecules. We have demonstrated that the surface can be used for the selective binding of avidin, followed by the binding of Arg-Gly-Asp-Ser-biotin and enhanced cell attachment by specific cell-ligand interactions. In conclusion, our one step immobilization method provides a simple tool to fabricate surfaces with controllable cell affinity.
Copyright © 2011 Acta Materialia Inc. Publishe
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Appendix V
The whole previous shebang .
Juggling and Parkinson’s
Andre Willers
29 Oct 2012
Synopsis:
Juggling is an ideal counter to early Parkinson’s Disease .
Discussion :
1.The problem is basically caused by the paring of neurons during the menopausal phase of human development . Sedentary persons run into the “Use or lose it” mechanisms . These mechanism are very basic , involving eye-muscle interactions to prevent dopamine apoptosis in seldom-used neurological pathways . Exercise alone is insufficient as it is too predictable .
2. Juggling with asymmetric objects fills the bill nicely . It is chaotically complex , so all the muscle-brain networks are continually used . Start with glass miniature bottles of whisky over a tile floor . The amygdala has to be involved . (Well , maybe over a carpet initially . ) Drink one when an exercise has been done successfully (positive feedback) .
Juggling will help with Restless Leg Syndrome .
3. Advanced students can walk around while juggling .
4.Parkinsonian crash and a Fall .
The neurological effects accumulate slowly , and culminates in a Crash . This is the neurological equivalent of a stroke . Balance is lost after heroic efforts and a heavy fall usually results
The problem is that the feedback to the muscles is too slow –a form of indecision .
. Depression sets in at a neurological level , usually typified by learned helplessness .
This is serious as a broken leg . No amount of “Pull yourself together” etc will not help .
5. Repair .
See Appendix I on how to do this .
6.Juggling
The laws of physics impose limits to indecision . Use it or lose it .
7. Old age wisdom
The neurological mechanisms used to translate 2-Dim systems into 3-Dim systems are essential for time-projections . Ie 3-Dim -> 4-Dim structures .
8. Tai-Chi Juggling .
Wait and hurry-up . This lights up just about every mind-body system .
Throwing things about is the frustration of Age .
Catching them is the wisdom of age .
Use it or lose it .
Andre
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Appendix I
The Plant Whisperer
Andre Willers
28 Oct 2012
Synopsis :
The hot breath (38C) and endogenous ethylene of the Plant Whisperer close to the plant induces hormonal changes in the plant .
Discussion :
Whispering to plants means being up close with your heat and breath . The hot-air envelope surrounding the body encompasses the plant and further concentrates ethylene .
1.Hormonal sensitivity .
Even small concentrations of high temperature right on the leaves (human breath about 1 ppb) will trigger plant reactions .See Appendix II for which reactions .
2.Humans enhance the effect by exposure to sunlight .See Appendix I . Don’t whisper to plants in the dark .
3. Smokers have about double the effect . See Appendix I .
4.Herd effect :
A breath of a herd of herbivores (cows , buffalo , dinosaurs ,etc) will act to synchronize a field .
The plants will release signalling molecules to amplify the effect of the ethylene from the herd’s breath . Maturity and reproduction in synchronization has major evolutionary survival benefits .
Remember the dung . The dung spreads trace elements (especially sulphur from lightning strikes) . The herd animals’ breeding is forced into synchronization with the plants .
A mutual feedback system evolves .
5.The Human Herd :
Each human is a herd of single-celled organisms . Some are more “human” than others . Some are symbiotic , some mutualistic , some commensal and some parasitic .
Just to make things interesting , they can switch roles . They have a large repertoire of roles hidden in the DNA and Epigenetic switches .
But a large number still have plant genes sensitive to ethylene . The strong suspicion arises that the human body uses ethylene to synchronize senescence . At least the mitochondria .
Note the bit about anaerobic conditions inhibiting ethylene formation . Aerobic exercise .
6.Rejuvenation :
We now have three mechanism affecting the whole and parts of the metabolism :
1.Molecular freeze (See Appendix III on hibernation using H2S)
2.Ethylene synchronizing the shebang in whole and parts .
3.Stem cells.
Stem cells are being produced all the time , but forced into age-synchronization by ethylene .
7.The Living forever trick .
We can play them off against each other to selectively synchronize a group of cells iro senescence , then freeze them using the H2S trick , then force neighbouring cells/organs into juvenility using ethylene during the unfreezing .
8.Notice that both H2S and ethylene (C2H4) are very permeable gases . Major players in the early evolution of life .
9. What is a poor man to do ?
All this sounds horribly expensive . Immortality for only the rich ?
What we want to do is to is boost age-synchronization using ethylene , then freeze it using H2S , then re-synchronize the age mechanism on the stem cells . In other words , give the stem cells an overwhelming advantage .
10.The Method:
1.Pre-prepare by taking silver nano particles (See Appendix II :inhibitors . Or wear silver jewelry . )
2.Take a whiff of ethylene . Wait three breaths .
3.Take a whiff of H2S . Wait three breaths .
4.Take a whiff of ethylene . Wait three breaths .
5.Repeat at least once a day.
This should rejuvenate some systems .
11.Why is such a simple system not known ? Because humans fear a lack of death .They are limited by the scope of their environment . Which is one of the reasons I am writing this .Death is only the beginning .
Hope that death is not but a dream .
Andre
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Appendix I
Human ethylene exhalation.
Release of ethylene in sunlight .
From 1 ppb to about 4 ppb after about 20 minutes .
http://www.ru.nl/tracegasfacility/@722413/pagina/
During lipid peroxidation traces of volatile hydrocarbons such as methane, ethane, ethylene, propane, butane, hexane and pentane are produced in very low concentrations and exhaled through breath and/or released through the skin.
Within 3 min after UV is turned on, the C2H4 emission starts to rise. After UV exposure, a two-phase decay in C2H4 emission was observed: a fast decay resulting from wash out by the lungs and blood and a slow long-term decay from the body tissue.
http://www.gasdetection.com/Toxnet_HSDB/c2h4.html
Body Burden:
Ethylene was detected in the expired air from 2 of 8 volunteers (1 smoker) during a test period of approximately 1 hr at quantities of 120 ug (smoker) and 0.91 ug(1).
[(1) Conkle JP et al; Arch Environ Health 30: 290-5 (1975)]**PEER REVIEWED**
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Appendix II
Ethylene as a sensitive plant hormone .
http://www.biologie.uni-hamburg.de/b-online/e31/31g.htm
Ethylene is a gaseous effector with a very simple structure. Nonetheless, ethylene has features that identify it as a hormone such as the fact that it is effective at nanomolar concentrations.
BLEECKER A.B. and KENDE H (2000) Ethylene: a gaseous signal molecule in plants. Annu. Rev. Cell Dev. Biol. 16: 1-18 (2000) http://cellbio.AnnualReviews.org/cgi/content/full/16/1/1
Inhibitors
Inhibitors are frequently used to study biosynthesis of ethylene and ethylene activity. AVG (aminoethoxyvinylglycine) und AOA (aminooxy-acetic acid) are inhibitors of ethylene biosynthesis. NBD (2, 5-norbornadiene) and Ag+ inhibit an ethylene response by binding to and blocking of the ethylene receptor. NBD is more specific as compared to silver ions.
Ethylene has evolved as the central regulator of cell death programs in plants. In roots and in some plants in stems, lack of oxygen induces formation of intercellular spaces, the so-called aerenchyma. Low oxygen conditions in waterlogged roots, for instance, result in lysogenous aerenchyma formation through programmed death of cells in the cortex. This process is controlled by ethylene, as is programmed death of endosperm cells during cereal seed development.
This reactions is oxygen-dependent. At anaerobic conditions ethylene formation is completely suppressed.
http://en.wikipedia.org/wiki/Ethylene
Environmental and biological triggers of ethylene
Environmental cues can induce the biosynthesis of the plant hormone. Flooding, drought, chilling, wounding, and pathogen attack can induce ethylene formation in the plant. In flooding, root suffers from lack of oxygen, or anoxia, which leads to the synthesis of 1-aminocyclopropane-1-carboxylic acid (ACC). ACC is transported upwards in the plant and then oxidized in leaves. The product, the ethylene causes epinasty of the leaves.
One speculation recently put forth for epinasty is the downward pointing leaves may act as pump handles in the wind. The ethylene may or may not additionally induce the growth of a valve in thexylem, but the idea would be that the plant would harness the power of the wind to pump out more water from the roots of the plants than would normally happen by transpiration alone.
List of plant responses to ethylene
Seedling triple response, thickening and shortening of hypocotyl with pronounced apical hook.
In pollination, when the pollen reaches the stigma, the precursor of the ethylene, ACC, is secreted to the petal, the ACC releases ethylene with ACC oxidase.
Stimulates leaf and flower senescence
Stimulates senescence of mature xylem cells in preparation for plant use
Induces leaf abscission
Induces seed germination
Induces root hair growth — increasing the efficiency of water and mineral absorption
Induces the growth of adventitious roots during flooding
Stimulates epinasty — leaf petiole grows out, leaf hangs down and curls into itself
Stimulates fruit ripening
Induces a climacteric rise in respiration in some fruit which causes a release of additional ethylene.
Affects gravitropism
Stimulates nutational bending
Inhibits stem growth and stimulates stem and cell broadening and lateral branch growth outside of seedling stage (see Hyponastic response)
Interference with auxin transport (with high auxin concentrations)
Inhibits shoot growth and stomatal closing except in some water plants or habitually flooded ones such as some rice varieties, where the opposite occurs (conserving CO2 and O2)
Induces flowering in pineapples
Inhibits short day induced flower initiation in Pharbitus nil[27] and Chrysanthemum morifolium[28
Ethylene action slows at lower temperatures.
At their minimum temperature levels, fruit is basically inactive and does not respond well to externally supplied ethylene.
Ethylene will penetrate most substances.
In fact, it will permeate through produce cardboard shipping boxes, wood and even concrete walls.
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Appendix III
http://andreswhy.blogspot.com Nov 2008
Hibernation and Cryogenics
Andre Willers
19 Nov 2008
Discussion :
Jessica Palmer pointed out on the 16th Nov 2008 that the primary problem with cryogenics seems to be in the re-establishment of metabolic processes after un-freezing .
But we have an already existing template for doing exactly that .
Hibernation .
See Appendix A
The evolutionary explanation is that during the transition-phase from methane/sulfur to oxygen atmosphere (circa 1.5 bn years ago) , there was a major advantage in suspending oxygen-driven systems if the organism found itself in a non-oxygen environment . It went into hibernation .
At the same time , alcohol was being excreted as a poison (like oxygen) . The ancestors of mitochondria (who could use low concentrations of oxygen or alcohol ) sought refuge in cells whose cell-walls were resistant (but not impervious) to alcohol transition .
Remember , alcohol is completely soluble in water , but oxygen is not . This difference drove the process . Alcohol concentrations in water could grow large , but oxygen-concentrations could not .
Mitochondria earned their keep by mopping up alcohol first and later converting oxygen to ATP . (The glucose and ketone metabolism came after this) . The ketone metabolism has never been very popular , because of the high loss-rate in excretory products , but has been kept as a third string on the bow . (Utilization of fat and protein-muscle reserves during low-glucose periods. )
Mitochondria thus has an exclusive preference of usage : alcohol , glucose , ketones in that order .
From experimental evidence (see Appendix A) , there is a genetic switch sensitive to the concentration of H2S to bring both the host cell and the mitochondrium to a state where all programmed molecular activity is suspended . (The power is switched off) .
But , of course , random beth(0) molecular activity due to temperature does not cease . Uncontrolled and anaerobic reactions still occur .
Freezing:
We get rid of most anaerobic organisms first .
Lots of sulfur , VitC and alcohol (fermented berries or carbohydrates in the stomach . A low acidity is required in the run-up to hibernation)
Then freeze .
Starting the contraption up again is a bit of a problem .
1. The power-plant :
The mitochondria needs to be primed with their preferred fuel (alcohol)
Oxygen needs to be infused .(Hyperbaric chamber)
2. Garbage disposal
The cellular garbage-disposal systems need to be activated . ATP from the powerplant needs to be allocated to breakdown-product disposal before the ATP is allocated to DNA/RNA production processes .
The garbage-disposal uses mechanisms that use sulfur to create the various vacuoles and ropes (cf mitosis) . Enough sulfur is vital .
Once again , oxygen and alcohol is used . Both are recognized by all systems as poisons to be removed as a first priority . They activate a quite sophisticated garbage-disposal system as H2S concentrations decrease .
3 . Flushing
All that garbage has to flushed away , preferably not through the kidneys or liver .
Use machines .
As H2S concentrations decrease , damage might occur due to PH fluctuations . Acidity (H2SO4 , etc) Buffering would be advisable .
4. Temperature:
Lots of water at 105 to 107 Fahrenheit for mammals , pulsing at pulserate(about 90 cycles per minute .)
This is to activate the chaperone systems and discourage opportunistic viruses .
5. Music
See http://andreswhy.blogspot.com “Music”
Play harmonious music so the vibrations can be felt throughout organism being thawed . This enhances timing-procedures by orders of magnitudes . Emergent order .
(A Beth(0.x) effect . )
The de-hibernization process must have an exact program at molecular level to reboot the cellular metabolism . Precisely what you need after a cryogenic procedure .
But its efficiency (ie your chance of survival) can be boosted by orders of magnitude by using the steps above .
Interesting notes:
1. Do hibernating animals like bears use alcohol-producing cells in their bloodstream to time hibernation? This can be tested .
2. Are there cold-chaperone molecules ? There should be .
3. Hibernation is easy . Nature has done all the hard work . Keeping the mechanism ticking over at a very slow rate enables cellular-garbage clearing for a relatively short period (6-8 months)
4. De-cryogenics is a bit harder , Beth(1) intervention is needed .
5. Alcohol-concentrations : we are talking about 1% to 2% imbibing . About 0.06% inside the cell . Ie , the cell-wall protects by a factor of about 30
6. Pulse-Cryogenics : alternate freezing and hibernation to get a better survival factor . For those who are too stupid to design a zero-entropy system .
Try : Life=negative entropy . Non-life = positive entropy . Design it so the sum is zero .
Andre
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Appendix A
From http://andreswhy.blogspot.com “ Birdflu Update-4” dated 29 Oct 2005
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Suspended Animation (the real thing!)
In 2005, Mark Roth and other scientists from the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle demonstrated that mice can be put into a state of suspended animation by applying a low dosage of hydrogen sulfide (80 ppm H2S) in the air. The breathing rate of the animals sank from 120 to 10 breaths per minute and their temperature fell from 37 °C to 2 °C above ambient temperature (in effect, they had become cold-blooded). The mice survived this procedure for 6 hours and afterwards showed no negative health consequences.
Such a hibernation occurs naturally in many mammals and also in toads, but not in mice. (Mice can fall into a state called clinical torpor when food shortage occurs). If the H2S-induced hibernation can be made to work in humans, it could be useful in the emergency management of severely injured patients, and in the conservation of donated organs.
As mentioned above, hydrogen sulfide binds to cytochrome oxidase and thereby prevents oxygen from binding, which apparently leads to the dramatic slowdown of metabolism. Animals and humans naturally produce some hydrogen sulfide in their body; researchers have proposed that the gas is used to regulate metabolic activity and body temperature, which would explain the above findings
Dosages of H2S:
Treatment involves immediate inhalation of amyl nitrite, injections of sodium nitrite, inhalation of pure oxygen, administration of bronchodilators to overcome eventual bronchospasm, and in some cases hyperbaric oxygen therapy.
Exposure to lower concentrations can result in eye irritation (because of the high alkality of the SH- anion), a sore throat and cough, shortness of breath, and fluid in the lungs. These symptoms usually go away in a few weeks. Long-term, low-level exposure may result in fatigue, loss of appetite, headaches, irritability, poor memory, and dizziness. Higher concentrations of 700-800 ppm tend to be fatal.
• 0.0047 ppm is the recognition threshold, the concentration at which 50% of humans can detect the characteristic rotten egg odor of hydrogen sulfide [2]
• 10-20 ppm is the borderline concentration for eye irritation.
• 50-100 ppm leads to eye damage.
• At 150-250 ppm the olfactory nerve is paralyzed after a few inhalations, and the sense of smell disappears, often together with awareness of danger,
• 320-530 ppm leads to pulmonary edema with the possibility of death.
• 530-1000 ppm causes strong stimulation of the central nervous system and rapid breathing, leading to loss of breathing;
o 800 ppm is the lethal concentration for 50% of humans for 5 minutes exposition (LC50).
Concentrations over 1000 ppm cause immediate collapse with loss of breathing, even after inhalation of a single breath.
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Appendix C
How to run faster .
Andre Willers
23 Jun 2012
Synopsis :
An optimal CO2 level enables humans to run faster and also avoid panic attacks .
Discussion :
This has to do with nerve transmission , not energy transfer .
CO2 , not O2 . See Appendix I
It means that if the athletes’s CO2 levels are below optimal , spontaneous (ie random) firing of muscle nerve fibres occur , drastically reducing performance . Remember , volitional muscles are grouped in antagonistic modes . The runner is literally retarding himself . Muscle cells are not contracting and relaxing in concert .
100 Meters dash
The athlete should hold his breath before the race , and not hyperventilate .
The same with diving .
In competitive athletics , use !click systems to meter CO2 levels at optimal .
See Appendix II on how to do it .
Interesting Asides
1.Panic Attacks : As you can see , this is very similar to so-called asthma attacks . The organism gears up to run like hell , but remains stationary . Things seize up . The link is the CO2 concentration . A PEP exhaler as described in in Appendix II should resolve a large number of problems .
2.Smokers : In the present environment , smokers (ie persons habituated to a high CO2 level) have to spend long periods of time when the CO2 level falls so low that anxiety and tetany occurs. Where they are not allowed to smoke . Especially when driving . Ignorance kills . They think it is something seriously wrong , instead of a CO2 withdrawal symptom . Panic attacks ensue .
3.Smoking athletes : Those pesky high-school guys who smoke and drink , but still win the 100 meters dash . Now you know how it works .
4.Golf and soccer : This very sensitive to random muscle firings . Ever wonder why you don’t play better ? Try a bit more CO2 . Or soccer , with that crucial shoot .
They take a deep breath .
Wrong ! CO2 level drops , primed muscles cells fire and the ball goes into orbit . Time after time .
You must hold your breath before the crucial moment .
This is already known in target-shooting . (Hold your breath , then squeeze the trigger) . But it is not because of the instability caused by breathing . It is the instability caused by too low CO2 levels , causing random contractions in the muscle fibres .
5.Global warming :As CO2 levels increase , one would expect that burst sports records would increase . And sports in general , as humans feel more capable .
Tetany is not epiphany .
Andre
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Appendix I
http://en.wikipedia.org/wiki/Tetany_(medical_sign)
Tetany
Tetany or tetany seizure is a medical sign consisting of the involuntary contraction of muscles, which may be caused by disease or other conditions that increase the action potential frequency. Muscle cramps that are caused by the disease tetanus are not classified as tetany; rather, they are due to a blocking of the inhibition to the neurons that supply muscles.
Mechanism
Low calcium levels in the bloodstream increase the permeability of neuronal membranes to sodium ions, causing a progressive depolarization, which increases the possibility of action potentials. If the plasma Ca2+ decreases to less than 50% of the normal value of 9.4 mg/dl, action potentials may be spontaneously generated, causing contraction of peripheral skeletal muscles.[1]
Low levels of carbon dioxide cause tetany by altering the albumin binding of calcium such that the ionized (physiologically influencing) fraction of calcium is reduced; the most common reason for low carbon dioxide levels is hyperventilation
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Appendix II
Bronchial Resonance
Andre Willers
14 Jun 2012
Synopsis :
Oscillating Positive Expiratory Pressure (OPEP) at about 15 Hz not only clears mucus , but also enhances oxygen uptake and prevents alveoli collapse .
Discussion :
A simple and elegant device (see Appendix II) induces resonances in the bronchial system at around 15 Hz ( 6-26 Hz) . This is a resonance of the mucus bacterial film , breaking it up . For evolutionary reasons , (See Appendix IV) , the filii of the airways operate optimally at this frequency . In other words , “hard” plaques liquefy and can be expelled .
This has an obvious effect on the bronchial system . Pumping out mucus (ie obstructions) from the upper regions of the bronchial tree causes a capillary pumping-out of muck out of the alveoli . Which frees them up for better gas transfer .
There is an ancillary effect . The walls of the narrower bronchial tubes also have a greater gas-transfer capability , once cleared of insulating mucus . They then operate more like the much more efficient bird-lungs . Will this trigger some epigenetic switching-on of bird-lung genes in the human genome ? I do not know , but it is likely .
Sports:
Any athlete will better his performance by using this technique .
There is an intriguing catch-up effect . The brain normally limits performance to 2/3 of maximal (Noakes) . But this takes time . Using OPEP just before an exertion means a multiplier of 3 of the increment in performance . Enough to win .
Instant Yoga :
The range 8 – 15 – 26 Hz is intriguingly close to brainwave frequencies . Using it will entrain brainwaves through pressure-wave fluctuation , especially at the synapse level . (ie neurotransmitter densities will fluctuate in resonance pressure resonances from the bronchial system ) .
Ohm mane padme sum !
Which brings us to the !Click language .
Or it’s descendant , the glottal stop . These interrupt the expiration in patterned ways . I tried it with the standard double-click (two teeth-clicks , followed by two tongue clicks during expiration using a Flutter device (see Appendix II)) . The effect was a enhanced clarity of mind , which I ascribe to enhanced oxygen intake . Be cautious . !Click combined with Flutter devices can have major biosystem effects .
Interesting Asides :
1.Are other plaques (eg arteries , alzheimers , infections , etc) also susceptible to resonances at around these frequencies ?
2Music , of course . Heavy rhythm , where the body resonates with the sound .
3.Smoking . At first glance , all smokers should use this technique . But if it leads to switching on some bird-lung genes , this would make them more susceptible to bird-flu . I simply do not know enough .
4.Coughing : this is an OPEP system . Time it . The frequency is close to 15 Hz, but only in short bursts. The artificial Flutter system is better .
5.Snoring : This is mostly on expiration (see Appendix III) . An attempt by the body system to induce a Flutter system on expiration . Thus , using a Flutter artificial system should cure most snoring problems .
6.Hiccups : it stops them cold . Also it’s little brother , that pesky reflux .(Heartburn)
7.Will it have an effect on the pylorus valve and the duodenal peristalsis , and hence Diabetes ?
(See http://andreswhy.blogspot.com “Cure for diabetes” May 2012)
I have no idea at present . Watch the next thrilling episode .
Where to get it in South Africa: See Appendix V
Life doesn’t suck . It is a blow job .
Andre .
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Appendix I
http://www.rcjournal.com/contents/10.07/10.07.1308.pdf
A good summation
Oscillatory PEP Therapy
OPEP therapy was first developed and described in Switzerland, as an adjunct or supplement to traditional airwayclearance methods.
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Appendix II
http://www.aptalispharma.com/pdf/flutter.pdf
When the oscillation frequency approximates the resonance
frequency of the pulmonary system, endobronchial pressure oscillations are amplified and result
in vibrations of the airways. The vibrations produced by these oscillations cause the "fluttering"
sensation from which the FLUTTER derived its name. These vibrations loosen mucus from the
airway walls. The intermittent increases in endobronchial pressure decrease the collapsibility of
the airways during exhalation, increasing the likelihood of clearing mucus from the
tracheobronchial tract. The airflow accelerations increase the velocity of the air being exhaled,
facilitating the movement of mucus up the airways
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Appendix III
More info
http://www.scah.uct.ac.za/paediatric-refresher-course-2009/presentations/tue/camphor/Morrow-CF-physiotherapy.pdf
http://en.wikipedia.org/wiki/Positive_end-expiratory_pressure
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Appendix IV
http://www.ncbi.nlm.nih.gov/pubmed/2929268
Mobilization of mucus by airway oscillations.
Freitag L, Kim CS, Long WM, Venegas J, Wanner A.
Source
Pulmonary Division, University of Miami, Mt. Sinai Medical Center.
Abstract
The effects of high frequency asymmetric airway oscillations on mucus clearance were evaluated in excised tracheas of sheep, in an animal model of excessive mucus production, and in patients with bronchiectasis. Asymmetric high frequency ventilation (15 Hz) with expiratory biased flow profiles (expiratory peak-flow greater than inspiratory peak-flow) could move mucus droplets towards the pharynx in rigid and flexible tracheas by gas-liquid interaction. In rigid tracheas the mucus was transported towards the periphery of the model lung if the oscillations were inspiratory biased. In very collapsible tracheas, however, even inspiratory biased oscillations moved the mucus cephalad. Parameters influencing direction and speed of mucus are airflow profile, peak-flow, airway compliance and lung resistance. Gamma-camera studies showed that in anesthetized dogs radiolabeled artificial mucus followed the direction of the bias during high frequency ventilation. In five human volunteers with bronchiectasis and excessive secretions the asymmetric airway oscillations were superimposed during spontaneous breathing using a mouthpiece. Airway wall vibrations following the pressure swings of the oscillator could be observed. During forced expiration inward bulging of the posterior membranes of trachea and bronchi occurred at the negative pressure phase of the oscillations. This event was associated with increased appearance of sputum in the central airways. We conclude that high frequency ventilation with asymmetric flow profiles applied via tube or mouthpiece might be an effective future treatment of mucostasis.
PMID:
2929268
[PubMed - indexed for MEDLINE]
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Appendix V
Where to get it South Africa
Price R90
MediTool
Pmb (0331) 903271
Jhb 082 900 7103
Cpt 082 871 6855
Pmb 082 900 3187
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Appendix D
Toughness and Sensitivity
Andre Willers
16 Nov 2012
Synopsis :
We look for a pill that enhances both toughness and sensitivity .
Discussion :
This is an old evolutionary problem solved many times .
Eyes : pupil sizes and brain pre-processing
Ears : sphincter muscles and brain pre-processing .
The Amygdala :
A fairly successful rapid-response pre-processing system , but prone to fixation .
What do monkeys do ? They throw things quite accurately and scream a lot .
Well , humans scream a lot , but it seems that the throwing bit is essential to restore the sensitivity portion of the amygdala response . This boils down to triceps combined with ocular targeting to reverse amygdala locks . Ie , throwing the pills hard into a big jug and thinking positively will have a very similar effect . The triceps must be involved .
Note the old cliché of the wife throwing crockery . Or slamming doors . Or backhanded slapping . Old hominin amygdala reprogramming systems .
Sports :
Of course , any major activity involving triceps and moving objects will be selected in civilized activities . Karate , darts , boxing , javelin , discus , crap dice , juggling , baseball , cricket , etc , etc.
Push-ups .
Well known to any military inductee . But why do they use it ? It is a system refined over at least 5 000 years . Because it is an easy and quick way to reprogram some amygdala routines on a sub-conscious level . (The Romans used pushing shields)
How many push-ups do we need ? The military like to overdo things to handle all the outliers and malingerers , but the critical factor seems to be that a full effort of the triceps muscle cells are needed . This can be as few as one , but usually four should be sufficient .
Four Slow pushups till the trembling point , followed by cachinnation (to trigger deep resolution of paradoxes) . The cachinnation (laughter) is essential to trigger release of neuro messengers for the stress-systems to stand down .
All this makes the system tougher . Less susceptible to outside changes .
But we also want it to be sensitive at the same time . The amygdala partly handles the toughness issue , but the sensitivity has to handled in virtual fashion .
Virtual limbs :
Simply create virtual limbs that have real tie-ins to brain systems . There are genetic tie-ins via insectile “extra-arms” . Most people can sense them , even feel them . These are pre-prepared brain systems derived from chimaeric insect systems . Phantom limbs are a confusion .
Why should the hind-brain have retained quite sophisticated insect limb handling capabilities ?
A spillover capability ? Are phantom limbs an advantage in resolving paradoxes in the normal mind-body complex ? At first glance , it would seem so . Evolution would use what is at hand , namely insectoid body pattern . In other words , store incompatible data in virtual limbs for which it already had a pattern .
Amputees with phantom limb problems could resolve them by sensing extra limbs .
Push-ups using phantom insectile limbs :
The amygdala reprogramming effect will be magnified non-linearly .
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The Sensitive part :
The toughness part is easy . Being sensitive at the same “time” is a quantum system . The systems are superposed .
The Trick is that the sensitive part is dominant and the tough part intermittent as the circumstances change . On average , the general rule of 1/3 Toughness and 2/3 Sensitivity holds .
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A Quantum Pill
At present there is no pill to resolve the problem . You will have to make do with the makeshits offered above .
But , in the near future you will be able to buy a quantum pill that forces various states to collapse .
Really nifty .
Alternately Yours
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Appendix E
A Vaccine for Overpopulation
Andre Willers
7 Apr 2012
Synopsis:
A prion disease removed natural epigenetic fertility controls circa 1704 AD . A vaccine is possible to train the immune system to recognize and remove the prion culprit .
Discussion :
See http://andreswhy.blogspot.com “Neanderthal Harbours” Apr 2012
Why a prion ?
Prions work by selectively disrupting the “read” process of the ribosome . Like putting a blank piece of paper in front of the letters to be photocopied . In scrapies and madcow , it is the “END” codon that is elided . The ribosome just keeps on copying proteins . See SciAm and NewScientist . This has a survival value for species in stressed circumstances , but is a bit tough on individuals .
Prions are also highly infectious . See
1.http://blogs.scientificamerican.com/observations/2011/05/19/natural-born-prion-killers-lichens-degrade-mad-cow-related-brain-pathogen/
“What has made prions difficult to control is their infamous durability. Boil water for a few minutes, and all the bacteria and viruses will be gone. Not so for the prion: it will be just fine, reaAs if it weren’t bad enough that deadly prions can survive boiling and radiation, now comes word that aerosolized forms of the pathogen can enter the nose and find their way to the brain, with fatal consequences.dy to infect. How does it fare in a dry heat of 600 degrees C? No problem there, either. How about ionizing radiation? Bring it on.”
2.scientificamerican.com/obseblogs.rvations/2011/01/13/bad-prion-breath-mad-cow-disease-agent-can-infect-via-the-air/
“As if it weren’t bad enough that deadly prions can survive boiling and radiation, now comes word that aerosolized forms of the pathogen can enter the nose and find their way to the brain, with fatal consequences.”
Epigenetics :
There is a sophisticated feedback process at epigenetic level monitoring population-level signals . A development of bacterial quorum-systems . Evolution does not favour Growth-without-limit , otherwise we would not have quorum systems . Remember , bacteria are the majority lifeform . This is the mistake Malthus made .
Malthus :
His Primary assumption was that populations grow to the limit of carrying capacity . This simply was not true before 1704 AD . But when he lived (1766-1874) it was , because the safety catches had been taken off . This happened because of a prion disease from some island off Scotland , rapidly infecting the rest of the world . And no disinfection then or now will work .
Is a vaccine possible ?
Yes. Simple , too .Take the negation of the END codon . The folded prion protein must have the precise lock-on DNA configuration and is thus targetable by tailored anti-bodies . A teensy-weensy problem is to zap only proteins with this configuration . But the heavy lifting has already been done . Neanderthal-derived families with few children should have the requisite molecules . And there are lots of them around the Med .
What does this mean ?
The overpopulation epidemic seems to have run it’s course in the first affected areas (Western Europe , North America) , but not yet in other parts of the world . The creation of a vaccine will cause major political problems . But it will probably share the characteristics of the original disease . Impossible to prevent , and very infectious . It is just the return to the natural state .
Interesting Asides :
1.What does the plants have to say about this ?
Remember , these are not conscious systems . But they are very effective .
Some plants have positive feedback relationship with humans . Grains and especially ones used in weaving . The introduction of woven cloths has always led to a population explosion . The fibres in close contact with the skin leads to positive feedbacks for prions suppressing epigenetic population control . Slow to start , but all plant weaves today encourages fertility .(By definition) . And they all target the same area in the epigenetic system . To find a vaccine , go to the nearest shop and buy any woven material . Look for prions .
2.Oh no !
Whisky . The Scottish Islands in 1704 AD exported mainly people , whisky and wool . All would carry the prions , but whisky the easiest of all . No wonder it was called the “Water of Life” . It was. People who drank it had more children . So , when you look for Person(0) , you know where to look . And look at whisky sales routes for subsequent spread of the infection . I guess this falls under the “some good news and some bad news” classification .
Should humans develop and employ an anti-fertility vaccine ?
They can do it now . But should they ? Well , they are going to do it in any case for short-term advantages , but they should simultaneously develop antidotes to the vaccine .
Places like Italy are already into negative population growth , and if you look at their fashions you can see why . (What! You think plants don’t have fashions ? Good luck with your sex-life . A fashionable fabric by definition promotes the sex-life of it’s partner .)
God’s Mercy
Instead of fashionably going extinct or superhuman , the possible pathways for human futures suddenly un-pinched from a neat two to a messy infinity . For some unfathomable reason the Powers-that-be decided to extend humanity’s term . The pinching-off branches have opened up . (The time-aspects were not predetermined . Think of it as a change in top-down chaotic attractors . You don’t have the terms)
Not my idea . I am but a time-limited pen , rather sourly recording .
Oh well .
Back to long-term planning .
“What God wants , God gets”
Andre
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Andre Willers
23 Nov 2012
Synopsis:
Dopamine-shortage Syndromes (like Wandering Legs Syndrome ) can be alleviated by horns , especially Rhino horns . But better relief can be gotten by drugs such as Pexola (refer Viagra and impotence).
Discussion :
1.The Restless Legs Syndrome (RLS).
See Appendix II
Restless Legs Syndrome is an extremely stressful syndrome partly triggered by Wandering Feet Syndrome (peripheral neuropathy) . The two are often confused . The stress causes a feedback effect of worsening tendencies to stress-related diseases like cancer . This relates diabetes and acrylamide damage to deeper dopamine-related diseases in the brain (eg Parkinson’s , addiction , RLS , etc)
See Appendix I
2.A simple management :
Pexola (trade name for Pramipexole)
The brakes on the dopamine feedback systems . Receptor site D2 applies .
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http://de.wikipedia.org/wiki/Pramipexol
Pramipexole is a dopamine agonist with high selectivity and specificity of D 2/3 - dopamine receptors . In the early stages of Parkinson's disease Pramipexole stimulates the presynaptic D2 autoreceptors, inhibiting the excessive dopamine synthesis and release. In the late stage reinforces the pramipexole-ending dopamine synthesis through stimulation and modulation of postsynaptic D 2 -. And D 3 receptors [5]
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3.Humans with large genetic components of Denisovan (South Asia and Pacific via Formosa) and Neanderthal (North-west Europe) genes will have neurological problems because of fast-twitch muscle demands . The fast-twitch muscles build up action potential chemicals , which in turn randomly activate while waiting for orders . This reverberates in the central brain as an anxiety and frantic efforts to justify the muscle activity . The brain is out of the decision loop .
Over the long term , this gives rise to highly undesirable makework activity by the brain (ie tremors in Parkinson’s) .
At the cellular level even more undesirable activities occur . See Appendix C at the end “How to run faster” . CO2 disposal and glucose-demand are not regulated properly .
The mitochondria do not rotate at an even speed . Like in a diesel-electric setup , it is most efficient if the mitochondria generates ATP at a steady rate .
4.CO2 concentrations .
As previously noted , it seems that humans had a genetical bottleneck episode (most likely Toba circa 72 000 years ago) when the CO2 levels where higher after most of the vegetation was burnt or decomposing . Plus some very old gene-adaptations from 65 MYA of the KT catastrophe activating .
Plus an H2S component of about 1/9 to 1/3 of 80 ppm causing activation of hind-brain (reptilian) functions inhibiting higher brain functions and promoting fast-twitch muscles .
5.What does all this mean ?
5.1 Athletes:
Sprinters and fast-twitch specialists will perform better if they have higher CO2 levels and an imperceptible whiff of about 15 ppm of H2S . About four slow pushups without breathing will also enable reserves held by amygdala mechanisms . See Appendix D
5.2 Diabetics and Parkinsonian’s
The same for them .
6.The rhino
Why bother with rhino-horn if a better alternative is available . The Viagra solution .
7.An interesting aside :
Very low concentrations of H2S as a trigger to hyper fertility .
See Appendix E .
Things grow like mad near volcano’s . Always supposed to be fertility of the soil . But more likely to be suppression of more primitive bacterial competitors due to H2S hibernation effect . Finally , near the mid-Atlantic fumaroles close to a Scottish isle is hopped to the human genepool in 1704 AD . Or was it simply a reactivation of an older gene ? However , the gene seems to be burning out , partly due to human burial practices . Large scale cremation always led to higher fertility rates .
A childless couple burning to have a child will be much more likely to conceive if she breathes a 9% higher CO2 concentration , as well as about 15 ppm of H2S after 4 trembling pushups .
Make of it what you wish .
Rhino’s don’t do Pushups .
It is up to you to do it for them .
It is not a dilemma .
Unilemmically yours
Andre
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Appendix I
Rhino Horns and Diabetes .
Andre Willers
11 Apr 2012.
Synopsis :
Rhino horn makes people feel better because it decreases “wandering feet “ of diabetes.
Better substitutes are available .
Discussion :
Fast twitch muscles require fast service by the nervous system . If this does not occur , local “pacemakers” step in . One locus is the heart (the heart pacemaker) . Another is situated at the base of the spine , where the long nerves connect to the spinal cord .
This well known as the source of phantom pain signals . (Lower back pain) .
But if the signals from the brain does not get to the muscles , the pacemaker activates . Muscles in the legs are stimulated , giving rise to a feeling of unease . These signals bypass the roadblocks which were due to the damage to transport mechanism of the nerves .
Certain states in the nerve is quantum forbidden , so the energy skips on . The signal travels faster .This enabled fast-twitch muscles to function and contract at frequencies not normal for nerves , but if it is not coordinated . a very uncomfortable feeling results in sleeplessness .
Rhino horn contains some chemicals that involve nerve transmission speeds .
http://www.jbc.org/content/128/1/181.full.pdf
Metabolic Sulphur , tyrosine(9%) and tryptophane (9%) seems to be an acceptable substitute .
Or exercise the fast twitch muscles in the legs by doing snap-kicks .
People susceptible to this would be descendants of Denisovans (eg Vietnamese) or Neanderthals (North-Western Europe) .
Note that the main fast-twitch muscle artists (lions ,etc) all eat hair and horn , which humans don’t .
Interesting asides:
1.Are human fast-twitch muscle artists like kung-fu experts more susceptible to diabetes ? The evidence seems to indicate it .
2. Can the rhino be saved like with Viagra ? Not unless the medical establishment acknowledges that there is a real effect , and offers a better alternative . Interestingly , the Vietnamese only started suffering from wandering feet after they got rich and stopped eating keratine food .
3.If keratine enables fast twitch nervous impulses , eating rhino-horn will give you a heart attack if you take beta-blockers as well .
Cow’s feet or chicken feet , anybody ?
Andre
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Appendix II
Juggling and Parkinson’s Disease II
Andre Willers
3 Nov 2012
Synopsis :
Juggling increases brain white-matter (experimental) . The reward mechanism is dopamine . The inhibition of (inhibition of dopamine) is partly governed by ethylene . Plant-whisperers get more organically active ethylene . The two combine in a synergistic way .
Discussion :
Some people have wondered what the connection between juggling and plant whispering is . The connection is dopamine via ethylene and it’s bio-active compounds . Plant-whispering alone will inhibit the inhibition of dopamine-forming , but it is enhanced by some orders of magnitude if juggling is included . Synergism .
You will need the building –blocks of the nervous system like omega-3 oils (flax seed oil) and cod liver oil .
Will a whiff of ethylene help (ie like ripe banana peels) ?
I have no idea . (Personally , I would rather be caught sniffing banana peels than whispering to plants . But maybe it’s just me .)
At least the juggling is recognized .
Juggling and Mirror-neurons
The essence of it .
Juggling forces the growth of new mirror-neuron networks . This can be enhanced by personalizing the juggling objects , with smiles on them . A mature network will recognize them (characters from well-known soapies , etc) . This works at even a single neuron level .
You can make it interactive . Something like WII . I don’t think purely virtual will work . There has to be muscle interaction .
By gad , a new toy ! Juggle your way into the soapies . Lots of money to be made from the old wrinklies .
Sports :
If you star player seems to have hit a plateau , grow some new mirror-neurons by juggling .
Business :
The new executive toy . A multi-tasking trainer that actually works .
Sex:
Your pleasure centres can juggle things in ways you have not even thought about .
Money :
New mirror-neurons gives you a new perspective .
Old Age:
Boredom is a killer . It is not that there are no new experiences , it is that any experience is translated along old neural paths . So they see only the ho-hum similarities , but not the new experience . For that you need some new pathways . Hence juggling .
Immune system :
The immune system gets bored as well (it is evolutionary programmed in.) It needs both muscle and brain new chemicals to activate new switches in the DNA-Epigenetic system . Unused systems gets apoptized via the epigenetic system .
Music :
Music to juggle by . I do not know of any , but doubtlessly there will soon be some .
What to do ?
1.Start juggling .
2.Take brain food chemicals like Omega fats .
3.Get a plant to whisper to . Your Confessor plant . Make sure it has no microphone in it .
Dopamaniacally yours
Andre
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Appendix I
http://www.findingdulcinea.com/news/science/2009/oct/Juggling-Shown-to-Change-Wiring-of-the-Brain.html
Juggling Shown to Change Wiring of the Brain
October 14, 2009 07:00 AM
by Denis Cummings
An Oxford University study has found that practicing a task such as juggling can alter the structure of the brain, indicating that the plasticity of the brain is greater than previously believed.
Juggling Increases White Matter
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Researchers tested the brains of 48 volunteers, half of whom were given weekly juggling lessons for six weeks. At the end of that period, their brains were tested again. Those who had juggled—regardless of whether they had become good jugglers—had a 5 percent increase in their brains’ white matter, the nerve strands that connect different parts of the brain. Those who hadn’t juggled had little change.
Previous studies have found that juggling and other mind tasks—such as cabbies memorizing the streets of London—increased the amount of grey matter, the portion of the brain that contains neurons. This is the first study to find that white matter is affected.
Lead researcher Dr. Heidi Johansen-Berg said that the research shows “the structure of the brain is ripe for change.” It raises hope that scientists can design treatments to improve brain function for those with dementia or neurodegenerative diseases such as multiple sclerosis, Alzheimer’s and Parkinson’s.
“Knowing that pathways in the brain can be enhanced may be significant in the long run in coming up with new treatments for neurological diseases, such as multiple sclerosis, where these pathways become degraded,” said Johansen-Berg.
The study, “Training induces changes in white-matter architecture,” is published in Nature Neuroscience.
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Appendix II
How to juggle .Note the “Aha!” hurdle . A general empowerment mechanism .
http://www.yoyoguy.com/info/ball/index2.html
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Appendix III
Gravity independent . Note mesons .
http://en.wikipedia.org/wiki/Juggling
Space
Juggling has been performed in space despite the fact that the micro-gravity environment of orbit deprives the juggled objects of the essential ability to fall. This is accomplished through 'two-person' juggling passing multiple objects between them. Juggling in space was demonstrated by Greg Chamitoff andRichard Garriott[citation needed] while Garriott was visiting the International Space Station as aSpaceflight Participant in October 2008. Their juggling of objects while in orbit was featured in 'Apogee of Fear', the first science fiction movie made in space by Garriott and 'Zero-G Magic', a magic show also recorded in space by Chamitoff and Garriott at that time.
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Appendix IV
A commercial application of ethylene inhibition of growth hormones , including dopamine .
http://www.ncbi.nlm.nih.gov/pubmed/21402183
Dopamine-assisted immobilization of poly(ethylene imine) based polymers for control of cell-surface interactions.
Tsai WB, Chien CY, Thissen H, Lai JY.
Source
Department of Chemical Engineering, National Taiwan University, 1 Roosevelt Road, Section 4, Taipei 106, Taiwan. weibortsai@ntu.edu.tw
Abstract
Non-fouling coatings play a critical role in many biomedical applications, such as diagnostic assay materials, biosensors, blood contacting devices and other implants. In the present work we have developed a facile, one step deposition method based on dopamine polymerization for preparation of non-fouling and biotinylated surfaces for biomedical applications. Poly(ethylene imine)-graft-poly(ethylene glycol) co-polymer (PEI-g-PEG) was mixed with an alkaline dopamine solution and then deposited onto different substrates. The dopamine coatings formed by this method were characterized by X-ray photoelectron spectroscopy (XPS), and the results indicated successful deposition of PEG. The resultant dopamine coatings formed on tissue culture polystyrene by this method revealed successful deposition of PEG, as shown by XPS. PEI-g-PEG/dopamine deposition for 2h inhibited the adsorption of serum proteins and the attachment of fibroblasts, suggesting that PEG molecules were immobilized in a sufficient density on the surface of the coating. Furthermore, co-deposition of PEI-g-PEG and PEI-g-biotin in alkaline dopamine solutions provided a cell-resisting background surface, at the same time providing accessible biotin molecules. We have demonstrated that the surface can be used for the selective binding of avidin, followed by the binding of Arg-Gly-Asp-Ser-biotin and enhanced cell attachment by specific cell-ligand interactions. In conclusion, our one step immobilization method provides a simple tool to fabricate surfaces with controllable cell affinity.
Copyright © 2011 Acta Materialia Inc. Publishe
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Appendix V
The whole previous shebang .
Juggling and Parkinson’s
Andre Willers
29 Oct 2012
Synopsis:
Juggling is an ideal counter to early Parkinson’s Disease .
Discussion :
1.The problem is basically caused by the paring of neurons during the menopausal phase of human development . Sedentary persons run into the “Use or lose it” mechanisms . These mechanism are very basic , involving eye-muscle interactions to prevent dopamine apoptosis in seldom-used neurological pathways . Exercise alone is insufficient as it is too predictable .
2. Juggling with asymmetric objects fills the bill nicely . It is chaotically complex , so all the muscle-brain networks are continually used . Start with glass miniature bottles of whisky over a tile floor . The amygdala has to be involved . (Well , maybe over a carpet initially . ) Drink one when an exercise has been done successfully (positive feedback) .
Juggling will help with Restless Leg Syndrome .
3. Advanced students can walk around while juggling .
4.Parkinsonian crash and a Fall .
The neurological effects accumulate slowly , and culminates in a Crash . This is the neurological equivalent of a stroke . Balance is lost after heroic efforts and a heavy fall usually results
The problem is that the feedback to the muscles is too slow –a form of indecision .
. Depression sets in at a neurological level , usually typified by learned helplessness .
This is serious as a broken leg . No amount of “Pull yourself together” etc will not help .
5. Repair .
See Appendix I on how to do this .
6.Juggling
The laws of physics impose limits to indecision . Use it or lose it .
7. Old age wisdom
The neurological mechanisms used to translate 2-Dim systems into 3-Dim systems are essential for time-projections . Ie 3-Dim -> 4-Dim structures .
8. Tai-Chi Juggling .
Wait and hurry-up . This lights up just about every mind-body system .
Throwing things about is the frustration of Age .
Catching them is the wisdom of age .
Use it or lose it .
Andre
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Appendix I
The Plant Whisperer
Andre Willers
28 Oct 2012
Synopsis :
The hot breath (38C) and endogenous ethylene of the Plant Whisperer close to the plant induces hormonal changes in the plant .
Discussion :
Whispering to plants means being up close with your heat and breath . The hot-air envelope surrounding the body encompasses the plant and further concentrates ethylene .
1.Hormonal sensitivity .
Even small concentrations of high temperature right on the leaves (human breath about 1 ppb) will trigger plant reactions .See Appendix II for which reactions .
2.Humans enhance the effect by exposure to sunlight .See Appendix I . Don’t whisper to plants in the dark .
3. Smokers have about double the effect . See Appendix I .
4.Herd effect :
A breath of a herd of herbivores (cows , buffalo , dinosaurs ,etc) will act to synchronize a field .
The plants will release signalling molecules to amplify the effect of the ethylene from the herd’s breath . Maturity and reproduction in synchronization has major evolutionary survival benefits .
Remember the dung . The dung spreads trace elements (especially sulphur from lightning strikes) . The herd animals’ breeding is forced into synchronization with the plants .
A mutual feedback system evolves .
5.The Human Herd :
Each human is a herd of single-celled organisms . Some are more “human” than others . Some are symbiotic , some mutualistic , some commensal and some parasitic .
Just to make things interesting , they can switch roles . They have a large repertoire of roles hidden in the DNA and Epigenetic switches .
But a large number still have plant genes sensitive to ethylene . The strong suspicion arises that the human body uses ethylene to synchronize senescence . At least the mitochondria .
Note the bit about anaerobic conditions inhibiting ethylene formation . Aerobic exercise .
6.Rejuvenation :
We now have three mechanism affecting the whole and parts of the metabolism :
1.Molecular freeze (See Appendix III on hibernation using H2S)
2.Ethylene synchronizing the shebang in whole and parts .
3.Stem cells.
Stem cells are being produced all the time , but forced into age-synchronization by ethylene .
7.The Living forever trick .
We can play them off against each other to selectively synchronize a group of cells iro senescence , then freeze them using the H2S trick , then force neighbouring cells/organs into juvenility using ethylene during the unfreezing .
8.Notice that both H2S and ethylene (C2H4) are very permeable gases . Major players in the early evolution of life .
9. What is a poor man to do ?
All this sounds horribly expensive . Immortality for only the rich ?
What we want to do is to is boost age-synchronization using ethylene , then freeze it using H2S , then re-synchronize the age mechanism on the stem cells . In other words , give the stem cells an overwhelming advantage .
10.The Method:
1.Pre-prepare by taking silver nano particles (See Appendix II :inhibitors . Or wear silver jewelry . )
2.Take a whiff of ethylene . Wait three breaths .
3.Take a whiff of H2S . Wait three breaths .
4.Take a whiff of ethylene . Wait three breaths .
5.Repeat at least once a day.
This should rejuvenate some systems .
11.Why is such a simple system not known ? Because humans fear a lack of death .They are limited by the scope of their environment . Which is one of the reasons I am writing this .Death is only the beginning .
Hope that death is not but a dream .
Andre
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Appendix I
Human ethylene exhalation.
Release of ethylene in sunlight .
From 1 ppb to about 4 ppb after about 20 minutes .
http://www.ru.nl/tracegasfacility/@722413/pagina/
During lipid peroxidation traces of volatile hydrocarbons such as methane, ethane, ethylene, propane, butane, hexane and pentane are produced in very low concentrations and exhaled through breath and/or released through the skin.
Within 3 min after UV is turned on, the C2H4 emission starts to rise. After UV exposure, a two-phase decay in C2H4 emission was observed: a fast decay resulting from wash out by the lungs and blood and a slow long-term decay from the body tissue.
http://www.gasdetection.com/Toxnet_HSDB/c2h4.html
Body Burden:
Ethylene was detected in the expired air from 2 of 8 volunteers (1 smoker) during a test period of approximately 1 hr at quantities of 120 ug (smoker) and 0.91 ug(1).
[(1) Conkle JP et al; Arch Environ Health 30: 290-5 (1975)]**PEER REVIEWED**
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Appendix II
Ethylene as a sensitive plant hormone .
http://www.biologie.uni-hamburg.de/b-online/e31/31g.htm
Ethylene is a gaseous effector with a very simple structure. Nonetheless, ethylene has features that identify it as a hormone such as the fact that it is effective at nanomolar concentrations.
BLEECKER A.B. and KENDE H (2000) Ethylene: a gaseous signal molecule in plants. Annu. Rev. Cell Dev. Biol. 16: 1-18 (2000) http://cellbio.AnnualReviews.org/cgi/content/full/16/1/1
Inhibitors
Inhibitors are frequently used to study biosynthesis of ethylene and ethylene activity. AVG (aminoethoxyvinylglycine) und AOA (aminooxy-acetic acid) are inhibitors of ethylene biosynthesis. NBD (2, 5-norbornadiene) and Ag+ inhibit an ethylene response by binding to and blocking of the ethylene receptor. NBD is more specific as compared to silver ions.
Ethylene has evolved as the central regulator of cell death programs in plants. In roots and in some plants in stems, lack of oxygen induces formation of intercellular spaces, the so-called aerenchyma. Low oxygen conditions in waterlogged roots, for instance, result in lysogenous aerenchyma formation through programmed death of cells in the cortex. This process is controlled by ethylene, as is programmed death of endosperm cells during cereal seed development.
This reactions is oxygen-dependent. At anaerobic conditions ethylene formation is completely suppressed.
http://en.wikipedia.org/wiki/Ethylene
Environmental and biological triggers of ethylene
Environmental cues can induce the biosynthesis of the plant hormone. Flooding, drought, chilling, wounding, and pathogen attack can induce ethylene formation in the plant. In flooding, root suffers from lack of oxygen, or anoxia, which leads to the synthesis of 1-aminocyclopropane-1-carboxylic acid (ACC). ACC is transported upwards in the plant and then oxidized in leaves. The product, the ethylene causes epinasty of the leaves.
One speculation recently put forth for epinasty is the downward pointing leaves may act as pump handles in the wind. The ethylene may or may not additionally induce the growth of a valve in thexylem, but the idea would be that the plant would harness the power of the wind to pump out more water from the roots of the plants than would normally happen by transpiration alone.
List of plant responses to ethylene
Seedling triple response, thickening and shortening of hypocotyl with pronounced apical hook.
In pollination, when the pollen reaches the stigma, the precursor of the ethylene, ACC, is secreted to the petal, the ACC releases ethylene with ACC oxidase.
Stimulates leaf and flower senescence
Stimulates senescence of mature xylem cells in preparation for plant use
Induces leaf abscission
Induces seed germination
Induces root hair growth — increasing the efficiency of water and mineral absorption
Induces the growth of adventitious roots during flooding
Stimulates epinasty — leaf petiole grows out, leaf hangs down and curls into itself
Stimulates fruit ripening
Induces a climacteric rise in respiration in some fruit which causes a release of additional ethylene.
Affects gravitropism
Stimulates nutational bending
Inhibits stem growth and stimulates stem and cell broadening and lateral branch growth outside of seedling stage (see Hyponastic response)
Interference with auxin transport (with high auxin concentrations)
Inhibits shoot growth and stomatal closing except in some water plants or habitually flooded ones such as some rice varieties, where the opposite occurs (conserving CO2 and O2)
Induces flowering in pineapples
Inhibits short day induced flower initiation in Pharbitus nil[27] and Chrysanthemum morifolium[28
Ethylene action slows at lower temperatures.
At their minimum temperature levels, fruit is basically inactive and does not respond well to externally supplied ethylene.
Ethylene will penetrate most substances.
In fact, it will permeate through produce cardboard shipping boxes, wood and even concrete walls.
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Appendix III
http://andreswhy.blogspot.com Nov 2008
Hibernation and Cryogenics
Andre Willers
19 Nov 2008
Discussion :
Jessica Palmer pointed out on the 16th Nov 2008 that the primary problem with cryogenics seems to be in the re-establishment of metabolic processes after un-freezing .
But we have an already existing template for doing exactly that .
Hibernation .
See Appendix A
The evolutionary explanation is that during the transition-phase from methane/sulfur to oxygen atmosphere (circa 1.5 bn years ago) , there was a major advantage in suspending oxygen-driven systems if the organism found itself in a non-oxygen environment . It went into hibernation .
At the same time , alcohol was being excreted as a poison (like oxygen) . The ancestors of mitochondria (who could use low concentrations of oxygen or alcohol ) sought refuge in cells whose cell-walls were resistant (but not impervious) to alcohol transition .
Remember , alcohol is completely soluble in water , but oxygen is not . This difference drove the process . Alcohol concentrations in water could grow large , but oxygen-concentrations could not .
Mitochondria earned their keep by mopping up alcohol first and later converting oxygen to ATP . (The glucose and ketone metabolism came after this) . The ketone metabolism has never been very popular , because of the high loss-rate in excretory products , but has been kept as a third string on the bow . (Utilization of fat and protein-muscle reserves during low-glucose periods. )
Mitochondria thus has an exclusive preference of usage : alcohol , glucose , ketones in that order .
From experimental evidence (see Appendix A) , there is a genetic switch sensitive to the concentration of H2S to bring both the host cell and the mitochondrium to a state where all programmed molecular activity is suspended . (The power is switched off) .
But , of course , random beth(0) molecular activity due to temperature does not cease . Uncontrolled and anaerobic reactions still occur .
Freezing:
We get rid of most anaerobic organisms first .
Lots of sulfur , VitC and alcohol (fermented berries or carbohydrates in the stomach . A low acidity is required in the run-up to hibernation)
Then freeze .
Starting the contraption up again is a bit of a problem .
1. The power-plant :
The mitochondria needs to be primed with their preferred fuel (alcohol)
Oxygen needs to be infused .(Hyperbaric chamber)
2. Garbage disposal
The cellular garbage-disposal systems need to be activated . ATP from the powerplant needs to be allocated to breakdown-product disposal before the ATP is allocated to DNA/RNA production processes .
The garbage-disposal uses mechanisms that use sulfur to create the various vacuoles and ropes (cf mitosis) . Enough sulfur is vital .
Once again , oxygen and alcohol is used . Both are recognized by all systems as poisons to be removed as a first priority . They activate a quite sophisticated garbage-disposal system as H2S concentrations decrease .
3 . Flushing
All that garbage has to flushed away , preferably not through the kidneys or liver .
Use machines .
As H2S concentrations decrease , damage might occur due to PH fluctuations . Acidity (H2SO4 , etc) Buffering would be advisable .
4. Temperature:
Lots of water at 105 to 107 Fahrenheit for mammals , pulsing at pulserate(about 90 cycles per minute .)
This is to activate the chaperone systems and discourage opportunistic viruses .
5. Music
See http://andreswhy.blogspot.com “Music”
Play harmonious music so the vibrations can be felt throughout organism being thawed . This enhances timing-procedures by orders of magnitudes . Emergent order .
(A Beth(0.x) effect . )
The de-hibernization process must have an exact program at molecular level to reboot the cellular metabolism . Precisely what you need after a cryogenic procedure .
But its efficiency (ie your chance of survival) can be boosted by orders of magnitude by using the steps above .
Interesting notes:
1. Do hibernating animals like bears use alcohol-producing cells in their bloodstream to time hibernation? This can be tested .
2. Are there cold-chaperone molecules ? There should be .
3. Hibernation is easy . Nature has done all the hard work . Keeping the mechanism ticking over at a very slow rate enables cellular-garbage clearing for a relatively short period (6-8 months)
4. De-cryogenics is a bit harder , Beth(1) intervention is needed .
5. Alcohol-concentrations : we are talking about 1% to 2% imbibing . About 0.06% inside the cell . Ie , the cell-wall protects by a factor of about 30
6. Pulse-Cryogenics : alternate freezing and hibernation to get a better survival factor . For those who are too stupid to design a zero-entropy system .
Try : Life=negative entropy . Non-life = positive entropy . Design it so the sum is zero .
Andre
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Appendix A
From http://andreswhy.blogspot.com “ Birdflu Update-4” dated 29 Oct 2005
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Suspended Animation (the real thing!)
In 2005, Mark Roth and other scientists from the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle demonstrated that mice can be put into a state of suspended animation by applying a low dosage of hydrogen sulfide (80 ppm H2S) in the air. The breathing rate of the animals sank from 120 to 10 breaths per minute and their temperature fell from 37 °C to 2 °C above ambient temperature (in effect, they had become cold-blooded). The mice survived this procedure for 6 hours and afterwards showed no negative health consequences.
Such a hibernation occurs naturally in many mammals and also in toads, but not in mice. (Mice can fall into a state called clinical torpor when food shortage occurs). If the H2S-induced hibernation can be made to work in humans, it could be useful in the emergency management of severely injured patients, and in the conservation of donated organs.
As mentioned above, hydrogen sulfide binds to cytochrome oxidase and thereby prevents oxygen from binding, which apparently leads to the dramatic slowdown of metabolism. Animals and humans naturally produce some hydrogen sulfide in their body; researchers have proposed that the gas is used to regulate metabolic activity and body temperature, which would explain the above findings
Dosages of H2S:
Treatment involves immediate inhalation of amyl nitrite, injections of sodium nitrite, inhalation of pure oxygen, administration of bronchodilators to overcome eventual bronchospasm, and in some cases hyperbaric oxygen therapy.
Exposure to lower concentrations can result in eye irritation (because of the high alkality of the SH- anion), a sore throat and cough, shortness of breath, and fluid in the lungs. These symptoms usually go away in a few weeks. Long-term, low-level exposure may result in fatigue, loss of appetite, headaches, irritability, poor memory, and dizziness. Higher concentrations of 700-800 ppm tend to be fatal.
• 0.0047 ppm is the recognition threshold, the concentration at which 50% of humans can detect the characteristic rotten egg odor of hydrogen sulfide [2]
• 10-20 ppm is the borderline concentration for eye irritation.
• 50-100 ppm leads to eye damage.
• At 150-250 ppm the olfactory nerve is paralyzed after a few inhalations, and the sense of smell disappears, often together with awareness of danger,
• 320-530 ppm leads to pulmonary edema with the possibility of death.
• 530-1000 ppm causes strong stimulation of the central nervous system and rapid breathing, leading to loss of breathing;
o 800 ppm is the lethal concentration for 50% of humans for 5 minutes exposition (LC50).
Concentrations over 1000 ppm cause immediate collapse with loss of breathing, even after inhalation of a single breath.
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Appendix C
How to run faster .
Andre Willers
23 Jun 2012
Synopsis :
An optimal CO2 level enables humans to run faster and also avoid panic attacks .
Discussion :
This has to do with nerve transmission , not energy transfer .
CO2 , not O2 . See Appendix I
It means that if the athletes’s CO2 levels are below optimal , spontaneous (ie random) firing of muscle nerve fibres occur , drastically reducing performance . Remember , volitional muscles are grouped in antagonistic modes . The runner is literally retarding himself . Muscle cells are not contracting and relaxing in concert .
100 Meters dash
The athlete should hold his breath before the race , and not hyperventilate .
The same with diving .
In competitive athletics , use !click systems to meter CO2 levels at optimal .
See Appendix II on how to do it .
Interesting Asides
1.Panic Attacks : As you can see , this is very similar to so-called asthma attacks . The organism gears up to run like hell , but remains stationary . Things seize up . The link is the CO2 concentration . A PEP exhaler as described in in Appendix II should resolve a large number of problems .
2.Smokers : In the present environment , smokers (ie persons habituated to a high CO2 level) have to spend long periods of time when the CO2 level falls so low that anxiety and tetany occurs. Where they are not allowed to smoke . Especially when driving . Ignorance kills . They think it is something seriously wrong , instead of a CO2 withdrawal symptom . Panic attacks ensue .
3.Smoking athletes : Those pesky high-school guys who smoke and drink , but still win the 100 meters dash . Now you know how it works .
4.Golf and soccer : This very sensitive to random muscle firings . Ever wonder why you don’t play better ? Try a bit more CO2 . Or soccer , with that crucial shoot .
They take a deep breath .
Wrong ! CO2 level drops , primed muscles cells fire and the ball goes into orbit . Time after time .
You must hold your breath before the crucial moment .
This is already known in target-shooting . (Hold your breath , then squeeze the trigger) . But it is not because of the instability caused by breathing . It is the instability caused by too low CO2 levels , causing random contractions in the muscle fibres .
5.Global warming :As CO2 levels increase , one would expect that burst sports records would increase . And sports in general , as humans feel more capable .
Tetany is not epiphany .
Andre
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Appendix I
http://en.wikipedia.org/wiki/Tetany_(medical_sign)
Tetany
Tetany or tetany seizure is a medical sign consisting of the involuntary contraction of muscles, which may be caused by disease or other conditions that increase the action potential frequency. Muscle cramps that are caused by the disease tetanus are not classified as tetany; rather, they are due to a blocking of the inhibition to the neurons that supply muscles.
Mechanism
Low calcium levels in the bloodstream increase the permeability of neuronal membranes to sodium ions, causing a progressive depolarization, which increases the possibility of action potentials. If the plasma Ca2+ decreases to less than 50% of the normal value of 9.4 mg/dl, action potentials may be spontaneously generated, causing contraction of peripheral skeletal muscles.[1]
Low levels of carbon dioxide cause tetany by altering the albumin binding of calcium such that the ionized (physiologically influencing) fraction of calcium is reduced; the most common reason for low carbon dioxide levels is hyperventilation
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Appendix II
Bronchial Resonance
Andre Willers
14 Jun 2012
Synopsis :
Oscillating Positive Expiratory Pressure (OPEP) at about 15 Hz not only clears mucus , but also enhances oxygen uptake and prevents alveoli collapse .
Discussion :
A simple and elegant device (see Appendix II) induces resonances in the bronchial system at around 15 Hz ( 6-26 Hz) . This is a resonance of the mucus bacterial film , breaking it up . For evolutionary reasons , (See Appendix IV) , the filii of the airways operate optimally at this frequency . In other words , “hard” plaques liquefy and can be expelled .
This has an obvious effect on the bronchial system . Pumping out mucus (ie obstructions) from the upper regions of the bronchial tree causes a capillary pumping-out of muck out of the alveoli . Which frees them up for better gas transfer .
There is an ancillary effect . The walls of the narrower bronchial tubes also have a greater gas-transfer capability , once cleared of insulating mucus . They then operate more like the much more efficient bird-lungs . Will this trigger some epigenetic switching-on of bird-lung genes in the human genome ? I do not know , but it is likely .
Sports:
Any athlete will better his performance by using this technique .
There is an intriguing catch-up effect . The brain normally limits performance to 2/3 of maximal (Noakes) . But this takes time . Using OPEP just before an exertion means a multiplier of 3 of the increment in performance . Enough to win .
Instant Yoga :
The range 8 – 15 – 26 Hz is intriguingly close to brainwave frequencies . Using it will entrain brainwaves through pressure-wave fluctuation , especially at the synapse level . (ie neurotransmitter densities will fluctuate in resonance pressure resonances from the bronchial system ) .
Ohm mane padme sum !
Which brings us to the !Click language .
Or it’s descendant , the glottal stop . These interrupt the expiration in patterned ways . I tried it with the standard double-click (two teeth-clicks , followed by two tongue clicks during expiration using a Flutter device (see Appendix II)) . The effect was a enhanced clarity of mind , which I ascribe to enhanced oxygen intake . Be cautious . !Click combined with Flutter devices can have major biosystem effects .
Interesting Asides :
1.Are other plaques (eg arteries , alzheimers , infections , etc) also susceptible to resonances at around these frequencies ?
2Music , of course . Heavy rhythm , where the body resonates with the sound .
3.Smoking . At first glance , all smokers should use this technique . But if it leads to switching on some bird-lung genes , this would make them more susceptible to bird-flu . I simply do not know enough .
4.Coughing : this is an OPEP system . Time it . The frequency is close to 15 Hz, but only in short bursts. The artificial Flutter system is better .
5.Snoring : This is mostly on expiration (see Appendix III) . An attempt by the body system to induce a Flutter system on expiration . Thus , using a Flutter artificial system should cure most snoring problems .
6.Hiccups : it stops them cold . Also it’s little brother , that pesky reflux .(Heartburn)
7.Will it have an effect on the pylorus valve and the duodenal peristalsis , and hence Diabetes ?
(See http://andreswhy.blogspot.com “Cure for diabetes” May 2012)
I have no idea at present . Watch the next thrilling episode .
Where to get it in South Africa: See Appendix V
Life doesn’t suck . It is a blow job .
Andre .
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Appendix I
http://www.rcjournal.com/contents/10.07/10.07.1308.pdf
A good summation
Oscillatory PEP Therapy
OPEP therapy was first developed and described in Switzerland, as an adjunct or supplement to traditional airwayclearance methods.
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Appendix II
http://www.aptalispharma.com/pdf/flutter.pdf
When the oscillation frequency approximates the resonance
frequency of the pulmonary system, endobronchial pressure oscillations are amplified and result
in vibrations of the airways. The vibrations produced by these oscillations cause the "fluttering"
sensation from which the FLUTTER derived its name. These vibrations loosen mucus from the
airway walls. The intermittent increases in endobronchial pressure decrease the collapsibility of
the airways during exhalation, increasing the likelihood of clearing mucus from the
tracheobronchial tract. The airflow accelerations increase the velocity of the air being exhaled,
facilitating the movement of mucus up the airways
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Appendix III
More info
http://www.scah.uct.ac.za/paediatric-refresher-course-2009/presentations/tue/camphor/Morrow-CF-physiotherapy.pdf
http://en.wikipedia.org/wiki/Positive_end-expiratory_pressure
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Appendix IV
http://www.ncbi.nlm.nih.gov/pubmed/2929268
Mobilization of mucus by airway oscillations.
Freitag L, Kim CS, Long WM, Venegas J, Wanner A.
Source
Pulmonary Division, University of Miami, Mt. Sinai Medical Center.
Abstract
The effects of high frequency asymmetric airway oscillations on mucus clearance were evaluated in excised tracheas of sheep, in an animal model of excessive mucus production, and in patients with bronchiectasis. Asymmetric high frequency ventilation (15 Hz) with expiratory biased flow profiles (expiratory peak-flow greater than inspiratory peak-flow) could move mucus droplets towards the pharynx in rigid and flexible tracheas by gas-liquid interaction. In rigid tracheas the mucus was transported towards the periphery of the model lung if the oscillations were inspiratory biased. In very collapsible tracheas, however, even inspiratory biased oscillations moved the mucus cephalad. Parameters influencing direction and speed of mucus are airflow profile, peak-flow, airway compliance and lung resistance. Gamma-camera studies showed that in anesthetized dogs radiolabeled artificial mucus followed the direction of the bias during high frequency ventilation. In five human volunteers with bronchiectasis and excessive secretions the asymmetric airway oscillations were superimposed during spontaneous breathing using a mouthpiece. Airway wall vibrations following the pressure swings of the oscillator could be observed. During forced expiration inward bulging of the posterior membranes of trachea and bronchi occurred at the negative pressure phase of the oscillations. This event was associated with increased appearance of sputum in the central airways. We conclude that high frequency ventilation with asymmetric flow profiles applied via tube or mouthpiece might be an effective future treatment of mucostasis.
PMID:
2929268
[PubMed - indexed for MEDLINE]
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Appendix V
Where to get it South Africa
Price R90
MediTool
Pmb (0331) 903271
Jhb 082 900 7103
Cpt 082 871 6855
Pmb 082 900 3187
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Appendix D
Toughness and Sensitivity
Andre Willers
16 Nov 2012
Synopsis :
We look for a pill that enhances both toughness and sensitivity .
Discussion :
This is an old evolutionary problem solved many times .
Eyes : pupil sizes and brain pre-processing
Ears : sphincter muscles and brain pre-processing .
The Amygdala :
A fairly successful rapid-response pre-processing system , but prone to fixation .
What do monkeys do ? They throw things quite accurately and scream a lot .
Well , humans scream a lot , but it seems that the throwing bit is essential to restore the sensitivity portion of the amygdala response . This boils down to triceps combined with ocular targeting to reverse amygdala locks . Ie , throwing the pills hard into a big jug and thinking positively will have a very similar effect . The triceps must be involved .
Note the old cliché of the wife throwing crockery . Or slamming doors . Or backhanded slapping . Old hominin amygdala reprogramming systems .
Sports :
Of course , any major activity involving triceps and moving objects will be selected in civilized activities . Karate , darts , boxing , javelin , discus , crap dice , juggling , baseball , cricket , etc , etc.
Push-ups .
Well known to any military inductee . But why do they use it ? It is a system refined over at least 5 000 years . Because it is an easy and quick way to reprogram some amygdala routines on a sub-conscious level . (The Romans used pushing shields)
How many push-ups do we need ? The military like to overdo things to handle all the outliers and malingerers , but the critical factor seems to be that a full effort of the triceps muscle cells are needed . This can be as few as one , but usually four should be sufficient .
Four Slow pushups till the trembling point , followed by cachinnation (to trigger deep resolution of paradoxes) . The cachinnation (laughter) is essential to trigger release of neuro messengers for the stress-systems to stand down .
All this makes the system tougher . Less susceptible to outside changes .
But we also want it to be sensitive at the same time . The amygdala partly handles the toughness issue , but the sensitivity has to handled in virtual fashion .
Virtual limbs :
Simply create virtual limbs that have real tie-ins to brain systems . There are genetic tie-ins via insectile “extra-arms” . Most people can sense them , even feel them . These are pre-prepared brain systems derived from chimaeric insect systems . Phantom limbs are a confusion .
Why should the hind-brain have retained quite sophisticated insect limb handling capabilities ?
A spillover capability ? Are phantom limbs an advantage in resolving paradoxes in the normal mind-body complex ? At first glance , it would seem so . Evolution would use what is at hand , namely insectoid body pattern . In other words , store incompatible data in virtual limbs for which it already had a pattern .
Amputees with phantom limb problems could resolve them by sensing extra limbs .
Push-ups using phantom insectile limbs :
The amygdala reprogramming effect will be magnified non-linearly .
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The Sensitive part :
The toughness part is easy . Being sensitive at the same “time” is a quantum system . The systems are superposed .
The Trick is that the sensitive part is dominant and the tough part intermittent as the circumstances change . On average , the general rule of 1/3 Toughness and 2/3 Sensitivity holds .
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A Quantum Pill
At present there is no pill to resolve the problem . You will have to make do with the makeshits offered above .
But , in the near future you will be able to buy a quantum pill that forces various states to collapse .
Really nifty .
Alternately Yours
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Appendix E
A Vaccine for Overpopulation
Andre Willers
7 Apr 2012
Synopsis:
A prion disease removed natural epigenetic fertility controls circa 1704 AD . A vaccine is possible to train the immune system to recognize and remove the prion culprit .
Discussion :
See http://andreswhy.blogspot.com “Neanderthal Harbours” Apr 2012
Why a prion ?
Prions work by selectively disrupting the “read” process of the ribosome . Like putting a blank piece of paper in front of the letters to be photocopied . In scrapies and madcow , it is the “END” codon that is elided . The ribosome just keeps on copying proteins . See SciAm and NewScientist . This has a survival value for species in stressed circumstances , but is a bit tough on individuals .
Prions are also highly infectious . See
1.http://blogs.scientificamerican.com/observations/2011/05/19/natural-born-prion-killers-lichens-degrade-mad-cow-related-brain-pathogen/
“What has made prions difficult to control is their infamous durability. Boil water for a few minutes, and all the bacteria and viruses will be gone. Not so for the prion: it will be just fine, reaAs if it weren’t bad enough that deadly prions can survive boiling and radiation, now comes word that aerosolized forms of the pathogen can enter the nose and find their way to the brain, with fatal consequences.dy to infect. How does it fare in a dry heat of 600 degrees C? No problem there, either. How about ionizing radiation? Bring it on.”
2.scientificamerican.com/obseblogs.rvations/2011/01/13/bad-prion-breath-mad-cow-disease-agent-can-infect-via-the-air/
“As if it weren’t bad enough that deadly prions can survive boiling and radiation, now comes word that aerosolized forms of the pathogen can enter the nose and find their way to the brain, with fatal consequences.”
Epigenetics :
There is a sophisticated feedback process at epigenetic level monitoring population-level signals . A development of bacterial quorum-systems . Evolution does not favour Growth-without-limit , otherwise we would not have quorum systems . Remember , bacteria are the majority lifeform . This is the mistake Malthus made .
Malthus :
His Primary assumption was that populations grow to the limit of carrying capacity . This simply was not true before 1704 AD . But when he lived (1766-1874) it was , because the safety catches had been taken off . This happened because of a prion disease from some island off Scotland , rapidly infecting the rest of the world . And no disinfection then or now will work .
Is a vaccine possible ?
Yes. Simple , too .Take the negation of the END codon . The folded prion protein must have the precise lock-on DNA configuration and is thus targetable by tailored anti-bodies . A teensy-weensy problem is to zap only proteins with this configuration . But the heavy lifting has already been done . Neanderthal-derived families with few children should have the requisite molecules . And there are lots of them around the Med .
What does this mean ?
The overpopulation epidemic seems to have run it’s course in the first affected areas (Western Europe , North America) , but not yet in other parts of the world . The creation of a vaccine will cause major political problems . But it will probably share the characteristics of the original disease . Impossible to prevent , and very infectious . It is just the return to the natural state .
Interesting Asides :
1.What does the plants have to say about this ?
Remember , these are not conscious systems . But they are very effective .
Some plants have positive feedback relationship with humans . Grains and especially ones used in weaving . The introduction of woven cloths has always led to a population explosion . The fibres in close contact with the skin leads to positive feedbacks for prions suppressing epigenetic population control . Slow to start , but all plant weaves today encourages fertility .(By definition) . And they all target the same area in the epigenetic system . To find a vaccine , go to the nearest shop and buy any woven material . Look for prions .
2.Oh no !
Whisky . The Scottish Islands in 1704 AD exported mainly people , whisky and wool . All would carry the prions , but whisky the easiest of all . No wonder it was called the “Water of Life” . It was. People who drank it had more children . So , when you look for Person(0) , you know where to look . And look at whisky sales routes for subsequent spread of the infection . I guess this falls under the “some good news and some bad news” classification .
Should humans develop and employ an anti-fertility vaccine ?
They can do it now . But should they ? Well , they are going to do it in any case for short-term advantages , but they should simultaneously develop antidotes to the vaccine .
Places like Italy are already into negative population growth , and if you look at their fashions you can see why . (What! You think plants don’t have fashions ? Good luck with your sex-life . A fashionable fabric by definition promotes the sex-life of it’s partner .)
God’s Mercy
Instead of fashionably going extinct or superhuman , the possible pathways for human futures suddenly un-pinched from a neat two to a messy infinity . For some unfathomable reason the Powers-that-be decided to extend humanity’s term . The pinching-off branches have opened up . (The time-aspects were not predetermined . Think of it as a change in top-down chaotic attractors . You don’t have the terms)
Not my idea . I am but a time-limited pen , rather sourly recording .
Oh well .
Back to long-term planning .
“What God wants , God gets”
Andre
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Wednesday, November 21, 2012
Optimizing the Professional
Optimizing the Professional .
Andre Willers
21 Nov 2012
“When in doubt , hit a ball.”
Synopsis:
Professionals are inundated by information and demands on their attention . Some simple algorithms make it more manageable .
Discussion:
1.This is an old problem , handled in various ways by evolutionary mechanisms
In a nutshell:
2.The sensory systems overwhelm the brain with trivia . This is handled by the synapse system , various hierarchical evaluation systems (like levels of the brain , eyes , ears , hunter-tracker systems , etc) , mirror-networks , focus(consciousness) .
3.The Amygdala Interrupt : vital messages trigger immediate action .
4.The end result is a clear , unambiguous action . The muscle activivty signals signify a reset .
5.What does this mean to our Professional ?
(For ease , I am going to use the example of a young medical doctor in private practise , married with two young children )
6.Personal Assistants:
The Human package comes with handy , built-in hunter-tracker neural-networks from human evolutionary history .
The doctor is trained to hunt the wily disease , noting the faintest tracks and spoor of symptoms . This entrains large portions of his neural structure .
These are his Personal Assistants , and they can be pretty insistant .
7.Reserves :
We can use the Reserve arguments , but their meaning should be clear . The General Reserve Argument takes as axiomatic that we do not know which element will fail or what the effect will be . However , for a professional large classes of failures of different likelihood and penalties are known . We can then get a better recalculation .
8.Triage .
Divide the demand on attention into three :
It is tempting to have too many categories of information flow and consequences , but then you are right back where you started .
8.1The Amygdala Interrupt :
Wife , children , own health , family gets interrupt priority .
8.2Prey Interrupt :
Patient (client) business . They pay for the Professional’s expertise .
8.3 The rest :
Take an asprin and make an appointment in the morning .
9.How do we get a number ?
We take a leaf out of the bean-counters’ handbook and see what the good doctor’s day is worth .
He charges (say) $100 per 15 min consultation . This gives a 24 hr/day value of 24*60/15*100=$9600
9.1Doctors Health :
9.1.1 Sleep 8 hrs = 8*4*100 = $3200 (weight 100)
9.1.2 Family time : This should be about 1/3 of time left after sleep and clients. The reserve after living priorities . Children are extraordinaly sensitive to this ratio . About 2hrs = $800 (Weight 100)
9.2Patients :
They pay for his full attention . Say 10hrs for 20 patients = $4 000 (Weight 100/20= 5)
9.3 How important is the remaining 4 hrs ?
We estimate it from the $400 / hr charge : Let the weight be R . Then
9600=(4000*100+4000*5+4*400*R)/(105+R)
9600(105+R)=8000*105+1600*R
9600*105-8000*105=(1600-9600)R
R= - 5 A negative number
What does this mean ?
It means that if you want a decent family life , the hourly rate is the critical factor , not the number of hours worked . For a doctor the breakeven point is 9600/4= 600 per 15 min consultation in the above example .
Otherwise the demands will eat you alive , regardless of any information handling schemes .
10.This was about 4 hours for upkeep of professional skills , etc . This is also the time segment targeted by useless memes . It can be eaten up by makework .
11.Electronic personal Assistants :
The new SkyVi by Google seems to be better than Siri . EVA is another option .
12. Real Personal Assistants . You can put all the above in a spreadsheet and calculate whether you would be better off by charging more per consultation . The 4 hour leeway simply means that you can lessen your losses , not enable the quality of life you desire .
13. Ceilings:
While most professionals can use AI’s to enhance their capability , doctors are still prohibited from using AI’s as adjuncts . If you can’t charge more , at least treat more per hour . And it can be done all over the planet quite legally . Most specialize and charge more for their worthless advice .
14.As for the information flood .
The triage should handle it . Use Google on personal computers to index and retrieve . AI’s like SkyVi anBetter yet , use one d Siri can be trained as Personal Assistants .
15.Remember: Humans are an hysterical species . Unless you are the cutting edge (leave the bleeding edge for children) , most of it is interesting garbage .Even worse now as everybody is vying for attention .
16. Facebook , twitter et al.
These operate via amygdala interrupts . “The phone rings , Answer it regardless “. Your underwear might be dirty . Do you have to answer the door when the postman knocks ? Maybe if it is the Postman of the Apocalypse , but the correct response is “return to sender” .
Simply delegate it to your kids .
Better yet , delegate it to one of the older , simpler turing AI’s . Will they even notice the difference .
17. Will you miss out on anything cutting edge ? Doubtful . The present system values repeatability above all . So , unless you are really front edge , it will make no difference .
18 The same with fiction . They have hit the singularity ceiling with a vengeance . Too stupid to distinguish between fantasy and singularity physics , the editors are betraying their readers . You won’t find any “Aha” new ideas . The editors don’t think there is a market for it . Typical lack of variety in a pre-singularity scenario .
Time for a revolution .
Apoptosis is the synopsis .
Andre
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Andre Willers
21 Nov 2012
“When in doubt , hit a ball.”
Synopsis:
Professionals are inundated by information and demands on their attention . Some simple algorithms make it more manageable .
Discussion:
1.This is an old problem , handled in various ways by evolutionary mechanisms
In a nutshell:
2.The sensory systems overwhelm the brain with trivia . This is handled by the synapse system , various hierarchical evaluation systems (like levels of the brain , eyes , ears , hunter-tracker systems , etc) , mirror-networks , focus(consciousness) .
3.The Amygdala Interrupt : vital messages trigger immediate action .
4.The end result is a clear , unambiguous action . The muscle activivty signals signify a reset .
5.What does this mean to our Professional ?
(For ease , I am going to use the example of a young medical doctor in private practise , married with two young children )
6.Personal Assistants:
The Human package comes with handy , built-in hunter-tracker neural-networks from human evolutionary history .
The doctor is trained to hunt the wily disease , noting the faintest tracks and spoor of symptoms . This entrains large portions of his neural structure .
These are his Personal Assistants , and they can be pretty insistant .
7.Reserves :
We can use the Reserve arguments , but their meaning should be clear . The General Reserve Argument takes as axiomatic that we do not know which element will fail or what the effect will be . However , for a professional large classes of failures of different likelihood and penalties are known . We can then get a better recalculation .
8.Triage .
Divide the demand on attention into three :
It is tempting to have too many categories of information flow and consequences , but then you are right back where you started .
8.1The Amygdala Interrupt :
Wife , children , own health , family gets interrupt priority .
8.2Prey Interrupt :
Patient (client) business . They pay for the Professional’s expertise .
8.3 The rest :
Take an asprin and make an appointment in the morning .
9.How do we get a number ?
We take a leaf out of the bean-counters’ handbook and see what the good doctor’s day is worth .
He charges (say) $100 per 15 min consultation . This gives a 24 hr/day value of 24*60/15*100=$9600
9.1Doctors Health :
9.1.1 Sleep 8 hrs = 8*4*100 = $3200 (weight 100)
9.1.2 Family time : This should be about 1/3 of time left after sleep and clients. The reserve after living priorities . Children are extraordinaly sensitive to this ratio . About 2hrs = $800 (Weight 100)
9.2Patients :
They pay for his full attention . Say 10hrs for 20 patients = $4 000 (Weight 100/20= 5)
9.3 How important is the remaining 4 hrs ?
We estimate it from the $400 / hr charge : Let the weight be R . Then
9600=(4000*100+4000*5+4*400*R)/(105+R)
9600(105+R)=8000*105+1600*R
9600*105-8000*105=(1600-9600)R
R= - 5 A negative number
What does this mean ?
It means that if you want a decent family life , the hourly rate is the critical factor , not the number of hours worked . For a doctor the breakeven point is 9600/4= 600 per 15 min consultation in the above example .
Otherwise the demands will eat you alive , regardless of any information handling schemes .
10.This was about 4 hours for upkeep of professional skills , etc . This is also the time segment targeted by useless memes . It can be eaten up by makework .
11.Electronic personal Assistants :
The new SkyVi by Google seems to be better than Siri . EVA is another option .
12. Real Personal Assistants . You can put all the above in a spreadsheet and calculate whether you would be better off by charging more per consultation . The 4 hour leeway simply means that you can lessen your losses , not enable the quality of life you desire .
13. Ceilings:
While most professionals can use AI’s to enhance their capability , doctors are still prohibited from using AI’s as adjuncts . If you can’t charge more , at least treat more per hour . And it can be done all over the planet quite legally . Most specialize and charge more for their worthless advice .
14.As for the information flood .
The triage should handle it . Use Google on personal computers to index and retrieve . AI’s like SkyVi anBetter yet , use one d Siri can be trained as Personal Assistants .
15.Remember: Humans are an hysterical species . Unless you are the cutting edge (leave the bleeding edge for children) , most of it is interesting garbage .Even worse now as everybody is vying for attention .
16. Facebook , twitter et al.
These operate via amygdala interrupts . “The phone rings , Answer it regardless “. Your underwear might be dirty . Do you have to answer the door when the postman knocks ? Maybe if it is the Postman of the Apocalypse , but the correct response is “return to sender” .
Simply delegate it to your kids .
Better yet , delegate it to one of the older , simpler turing AI’s . Will they even notice the difference .
17. Will you miss out on anything cutting edge ? Doubtful . The present system values repeatability above all . So , unless you are really front edge , it will make no difference .
18 The same with fiction . They have hit the singularity ceiling with a vengeance . Too stupid to distinguish between fantasy and singularity physics , the editors are betraying their readers . You won’t find any “Aha” new ideas . The editors don’t think there is a market for it . Typical lack of variety in a pre-singularity scenario .
Time for a revolution .
Apoptosis is the synopsis .
Andre
xxxxxxxxxxxxxxxxxxxxxxxx
Sunday, November 18, 2012
Zinc and Sexiness
Zinc and Sexiness
Andre Willers
18 Nov 2012
Synopsis:
Zinc re-absorption via the inner thighs plays a large role in activating homonin sexual pheromones and athletic success .
Discussion :
1.Any chase splatters the inside of the thighs of a cursorial raptor human or canine with urine .
2.The urine contains elements of zinc , which are absorbed through the inner thigh skin and acts as hormones (see Appendix I and III) .
3.This triggers both pheromone production and long-term pheromone receptor site production . Chasing is a cursorial raptor mating ritual .
4.The switch-off : after a successful mating , the positive feedback mechanism (ie sweet taste of Sex) is switched off through zinc-sulfate (see Appendix II) .
5.In other words , over zinc supplements will do horrible things to your sex life and enjoyment of food . The two are related .
6.Athletes:
Distance athletes routinely pee in their pants . What they don’t realise that this is essential to that “Aha!” endorphine high . It is actually a sexual high .
Of course we can mimic this : a Zinc spray on the inner thighs and NO deoderants should trigger a randy surge to the winning post . (Wifey better be handy.)
Sexual systems are mobilized and extreme violence can occur .
See http//:andreswhy.blogspot.com “Post Coital syndrome” Aug 2005
7.The inner thighs of cursorial raptors :
This needs some more examination , especially as regards re-absorption of trace elements acting like hormones .
8. There has been millions of dedicated researchers on this very subject .
In the spirit of dedicated Scientific Inquiry .
Andre .
xxxxxxxxxxxxxxxxxxxxxxxxx
Appendix I
Zinc and oderant receptors (ie pheromones) are cousins , genetically speaking .
http://www.biomedcentral.com/1471-2148/8/176
The sequencing of the human genome uncovered that a large number of gene families are often arranged in a clustered organization [1-3]. C2H2 zinc finger (C2H2-ZNF) genes make up ~2% of all the human genes and represent the second largest gene family in humans after the odorant receptor family [4-7].
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Appendix II
Zinc affects taste by blocking sweeteners (ie by blocking positive positive feedback mechanisms in the mouth .)
http://chemse.oxfordjournals.org/content/29/6/513.full
Abstract
We investigated the ability of zinc sulfate (5, 25, 50 mM) to inhibit the sweetness of 12 chemically diverse sweeteners, which were all intensity matched to 300 mM sucrose [800 mM glucose, 475 mM fructose, 3.25 mM aspartame, 3.5 mM saccharin, 12 mM sodium cyclamate, 14 mM acesulfame-K, 1.04 M sorbitol, 0.629 mM sucralose, 0.375 mM neohesperidin dihydrochalcone (NHDC), 1.5 mM stevioside and 0.0163 mM thaumatin]. Zinc sulfate inhibited the sweetness of most compounds in a concentration dependent manner, peaking with 80% inhibition by 50 mM. Curiously, zinc sulfate never inhibited the sweetness of Na-cyclamate. This suggests that Na-cyclamate may access a sweet taste mechanism that is different from the other sweeteners, which were inhibited uniformly (except thaumatin) at every concentration of zinc sulfate. We hypothesize that this set of compounds either accesses a single receptor or multiple receptors that are inhibited equally by zinc sulfate at each concentration.
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Appendix III
There is a lot of Zinc in urine .
http://www.fao.org/docrep/004/Y2809E/y2809e0m.htm
Zinc is lost from the body through the kidneys, skin, and intestine. The endogenous intestinal losses can vary from 7 mmol/day (0.5 mg/day) to more than 45 mmol/day (3 mg/day), depending on zinc intake (4). Urinary and skin losses are of the order of 7-10 mmol/day (0.5-0.7 mg/day) each and depend less on normal variations in zinc intake (4). Starvation and muscle catabolism increase zinc losses in urine. Strenuous exercise and elevated ambient temperatures could lead to losses by perspiration.
The body has no zinc stores in the conventional sense. In conditions of bone resorption and tissue catabolism, zinc is released and may be re-utilised to some extent. Human experimental studies with low-zinc diets 2.6-3.6 mg/day (40-55 mmol/day) have shown that circulating zinc levels and activities of zinc-containing enzymes can be maintained within normal range over several months (5, 6), which highlights the efficiency of the zinc homeostasis mechanism. Controlled depletion-repletion studies in humans have shown that changes in the endogenous excretion of zinc through the kidneys, intestine, and skin and changes in absorptive efficiency are how body zinc content is maintained (7-10). The underlying mechanisms are poorly understood.
Xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Andre Willers
18 Nov 2012
Synopsis:
Zinc re-absorption via the inner thighs plays a large role in activating homonin sexual pheromones and athletic success .
Discussion :
1.Any chase splatters the inside of the thighs of a cursorial raptor human or canine with urine .
2.The urine contains elements of zinc , which are absorbed through the inner thigh skin and acts as hormones (see Appendix I and III) .
3.This triggers both pheromone production and long-term pheromone receptor site production . Chasing is a cursorial raptor mating ritual .
4.The switch-off : after a successful mating , the positive feedback mechanism (ie sweet taste of Sex) is switched off through zinc-sulfate (see Appendix II) .
5.In other words , over zinc supplements will do horrible things to your sex life and enjoyment of food . The two are related .
6.Athletes:
Distance athletes routinely pee in their pants . What they don’t realise that this is essential to that “Aha!” endorphine high . It is actually a sexual high .
Of course we can mimic this : a Zinc spray on the inner thighs and NO deoderants should trigger a randy surge to the winning post . (Wifey better be handy.)
Sexual systems are mobilized and extreme violence can occur .
See http//:andreswhy.blogspot.com “Post Coital syndrome” Aug 2005
7.The inner thighs of cursorial raptors :
This needs some more examination , especially as regards re-absorption of trace elements acting like hormones .
8. There has been millions of dedicated researchers on this very subject .
In the spirit of dedicated Scientific Inquiry .
Andre .
xxxxxxxxxxxxxxxxxxxxxxxxx
Appendix I
Zinc and oderant receptors (ie pheromones) are cousins , genetically speaking .
http://www.biomedcentral.com/1471-2148/8/176
The sequencing of the human genome uncovered that a large number of gene families are often arranged in a clustered organization [1-3]. C2H2 zinc finger (C2H2-ZNF) genes make up ~2% of all the human genes and represent the second largest gene family in humans after the odorant receptor family [4-7].
Xxxxxxxxxxxxxxxxxxx
Appendix II
Zinc affects taste by blocking sweeteners (ie by blocking positive positive feedback mechanisms in the mouth .)
http://chemse.oxfordjournals.org/content/29/6/513.full
Abstract
We investigated the ability of zinc sulfate (5, 25, 50 mM) to inhibit the sweetness of 12 chemically diverse sweeteners, which were all intensity matched to 300 mM sucrose [800 mM glucose, 475 mM fructose, 3.25 mM aspartame, 3.5 mM saccharin, 12 mM sodium cyclamate, 14 mM acesulfame-K, 1.04 M sorbitol, 0.629 mM sucralose, 0.375 mM neohesperidin dihydrochalcone (NHDC), 1.5 mM stevioside and 0.0163 mM thaumatin]. Zinc sulfate inhibited the sweetness of most compounds in a concentration dependent manner, peaking with 80% inhibition by 50 mM. Curiously, zinc sulfate never inhibited the sweetness of Na-cyclamate. This suggests that Na-cyclamate may access a sweet taste mechanism that is different from the other sweeteners, which were inhibited uniformly (except thaumatin) at every concentration of zinc sulfate. We hypothesize that this set of compounds either accesses a single receptor or multiple receptors that are inhibited equally by zinc sulfate at each concentration.
Xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Appendix III
There is a lot of Zinc in urine .
http://www.fao.org/docrep/004/Y2809E/y2809e0m.htm
Zinc is lost from the body through the kidneys, skin, and intestine. The endogenous intestinal losses can vary from 7 mmol/day (0.5 mg/day) to more than 45 mmol/day (3 mg/day), depending on zinc intake (4). Urinary and skin losses are of the order of 7-10 mmol/day (0.5-0.7 mg/day) each and depend less on normal variations in zinc intake (4). Starvation and muscle catabolism increase zinc losses in urine. Strenuous exercise and elevated ambient temperatures could lead to losses by perspiration.
The body has no zinc stores in the conventional sense. In conditions of bone resorption and tissue catabolism, zinc is released and may be re-utilised to some extent. Human experimental studies with low-zinc diets 2.6-3.6 mg/day (40-55 mmol/day) have shown that circulating zinc levels and activities of zinc-containing enzymes can be maintained within normal range over several months (5, 6), which highlights the efficiency of the zinc homeostasis mechanism. Controlled depletion-repletion studies in humans have shown that changes in the endogenous excretion of zinc through the kidneys, intestine, and skin and changes in absorptive efficiency are how body zinc content is maintained (7-10). The underlying mechanisms are poorly understood.
Xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Friday, November 16, 2012
Toughness and Sensitivity
Toughness and Sensitivity
Andre Willers
16 Nov 2012
Synopsis :
We look for a pill that enhances both toughness and sensitivity .
Discussion :
This is an old evolutionary problem solved many times .
Eyes : pupil sizes and brain pre-processing
Ears : sphincter muscles and brain pre-processing .
The Amygdala :
A fairly successful rapid-response pre-processing system , but prone to fixation .
What do monkeys do ? They throw things quite accurately and scream a lot .
Well , humans scream a lot , but it seems that the throwing bit is essential to restore the sensitivity portion of the amygdala response . This boils down to triceps combined with ocular targeting to reverse amygdala locks . Ie , throwing the pills hard into a big jug and thinking positively will have a very similar effect . The triceps must be involved .
Note the old cliché of the wife throwing crockery . Or slamming doors . Or backhanded slapping . Old hominin amygdala reprogramming systems .
Sports :
Of course , any major activity involving triceps and moving objects will be selected in civilized activities . Karate , darts , boxing , javelin , discus , crap dice , juggling , baseball , cricket , etc , etc.
Push-ups .
Well known to any military inductee . But why do they use it ? It is a system refined over at least 5 000 years . Because it is an easy and quick way to reprogram some amygdala routines on a sub-conscious level . (The Romans used pushing shields)
How many push-ups do we need ? The military like to overdo things to handle all the outliers and malingerers , but the critical factor seems to be that a full effort of the triceps muscle cells are needed . This can be as few as one , but usually four should be sufficient .
Four Slow pushups till the trembling point , followed by cachinnation (to trigger deep resolution of paradoxes) . The cachinnation (laughter) is essential to trigger release of neuro messengers for the stress-systems to stand down .
All this makes the system tougher . Less susceptible to outside changes .
But we also want it to be sensitive at the same time . The amygdala partly handles the toughness issue , but the sensitivity has to handled in virtual fashion .
Virtual limbs :
Simply create virtual limbs that have real tie-ins to brain systems . There are genetic tie-ins via insectile “extra-arms” . Most people can sense them , even feel them . These are pre-prepared brain systems derived from chimaeric insect systems . Phantom limbs are a confusion .
Why should the hind-brain have retained quite sophisticated insect limb handling capabilities ?
A spillover capability ? Are phantom limbs an advantage in resolving paradoxes in the normal mind-body complex ? At first glance , it would seem so . Evolution would use what is at hand , namely insectoid body pattern . In other words , store incompatible data in virtual limbs for which it already had a pattern .
Amputees with phantom limb problems could resolve them by sensing extra limbs .
Push-ups using phantom insectile limbs :
The amygdala reprogramming effect will be magnified non-linearly .
Xxxxxxxxxxxxxxxxxxxx
The Sensitive part :
The toughness part is easy . Being sensitive at the same “time” is a quantum system . The systems are superposed .
The Trick is that the sensitive part is dominant and the tough part intermittent as the circumstances change . On average , the general rule of 1/3 Toughness and 2/3 Sensitivity holds .
Xxxxxxxxxxxx
A Quantum Pill
At present there is no pill to resolve the problem . You will have to make do with the makeshits offered above .
But , in the near future you will be able to buy a quantum pill that forces various states to collapse .
Really nifty .
Alternately Yours
Andre
xxxxxxxxxxxxxxxxxxxxxxxxx
Andre Willers
16 Nov 2012
Synopsis :
We look for a pill that enhances both toughness and sensitivity .
Discussion :
This is an old evolutionary problem solved many times .
Eyes : pupil sizes and brain pre-processing
Ears : sphincter muscles and brain pre-processing .
The Amygdala :
A fairly successful rapid-response pre-processing system , but prone to fixation .
What do monkeys do ? They throw things quite accurately and scream a lot .
Well , humans scream a lot , but it seems that the throwing bit is essential to restore the sensitivity portion of the amygdala response . This boils down to triceps combined with ocular targeting to reverse amygdala locks . Ie , throwing the pills hard into a big jug and thinking positively will have a very similar effect . The triceps must be involved .
Note the old cliché of the wife throwing crockery . Or slamming doors . Or backhanded slapping . Old hominin amygdala reprogramming systems .
Sports :
Of course , any major activity involving triceps and moving objects will be selected in civilized activities . Karate , darts , boxing , javelin , discus , crap dice , juggling , baseball , cricket , etc , etc.
Push-ups .
Well known to any military inductee . But why do they use it ? It is a system refined over at least 5 000 years . Because it is an easy and quick way to reprogram some amygdala routines on a sub-conscious level . (The Romans used pushing shields)
How many push-ups do we need ? The military like to overdo things to handle all the outliers and malingerers , but the critical factor seems to be that a full effort of the triceps muscle cells are needed . This can be as few as one , but usually four should be sufficient .
Four Slow pushups till the trembling point , followed by cachinnation (to trigger deep resolution of paradoxes) . The cachinnation (laughter) is essential to trigger release of neuro messengers for the stress-systems to stand down .
All this makes the system tougher . Less susceptible to outside changes .
But we also want it to be sensitive at the same time . The amygdala partly handles the toughness issue , but the sensitivity has to handled in virtual fashion .
Virtual limbs :
Simply create virtual limbs that have real tie-ins to brain systems . There are genetic tie-ins via insectile “extra-arms” . Most people can sense them , even feel them . These are pre-prepared brain systems derived from chimaeric insect systems . Phantom limbs are a confusion .
Why should the hind-brain have retained quite sophisticated insect limb handling capabilities ?
A spillover capability ? Are phantom limbs an advantage in resolving paradoxes in the normal mind-body complex ? At first glance , it would seem so . Evolution would use what is at hand , namely insectoid body pattern . In other words , store incompatible data in virtual limbs for which it already had a pattern .
Amputees with phantom limb problems could resolve them by sensing extra limbs .
Push-ups using phantom insectile limbs :
The amygdala reprogramming effect will be magnified non-linearly .
Xxxxxxxxxxxxxxxxxxxx
The Sensitive part :
The toughness part is easy . Being sensitive at the same “time” is a quantum system . The systems are superposed .
The Trick is that the sensitive part is dominant and the tough part intermittent as the circumstances change . On average , the general rule of 1/3 Toughness and 2/3 Sensitivity holds .
Xxxxxxxxxxxx
A Quantum Pill
At present there is no pill to resolve the problem . You will have to make do with the makeshits offered above .
But , in the near future you will be able to buy a quantum pill that forces various states to collapse .
Really nifty .
Alternately Yours
Andre
xxxxxxxxxxxxxxxxxxxxxxxxx
Wednesday, November 14, 2012
Origins of Peace and War II
Origins of Peace and War II
Andre Willers
14 Nov 2012
“The Real Gates of Janus are closing”
Synopsis:
General War is becoming less prevalent as technology enables smart targeting of particular prey .
Discussion:
War results from the certain targets being designated as “prey” by social authorities .
See Appendix I for a further discussion . But this was written in 2007 . Things have changed . (A definition of the run-up into the Singularity . )
Prey are now designated by social media like Facebook and Twitter .
Very democratic and short-term .
But is there a long-term ?
Closing in on the Singularity , things change faster and faster . There is no long-term in any meaningful terms .
The Hysterical Focus :
Described in Appendix II . This is the mechanism whereby Prey is selected by the Social Organism . For examples see what happened to Gaddafi , Murdock , BBC etc . What is happening to Assad .
Notice there is no workable use of the Jingoism used before by ruling classes to divert attention into a General War . The fine detail of the social media makes this impossible .
What does this mean ?
It means that fighting does not cease , but it gets chopped up into smaller , manageable pieces , not large Wars .
These smaller pieces can be handled by the Ostrum Principles .
So , we are seeing a not so quiet revolution where everybody settles their differences on a small scale , and declines an invitation to a general conflagration .
The humans who actually create these dangerous toys decline to play any more .
xxxxx
An interesting aside :
The sociopathic switch will be selected against . A lot of sociopaths will suddenly become kind and caring . (It is a epigenetic switch , not DNA . The chemicals are air-borne and touch .) . Won’t help much for psychopaths , but there might be some “spontaneous remission “ for some schizophrenics .
Kindness is in the air .
You can already see it in the hierarchical chiefs beating their breasts and saying “ Sorry”
Oh well . Lack of conscience works on a small scale as well . As long as the bastards do not get their hands on large levers of power .
Xxxxx
Summation :
“Plus la change”
The Matriarchy has won on Earth . But the off-Earth systems are the equivalent of the horse-nomads
And so it repeats .
I thought it would mercifully end with extinction of humans about 2060 AD , but space-nomads and the Matriarchy seems to be God’s little joke .
Singularity only for some .
The Singularities will follow Riemann’s Expansion , if only you knew the dimensions .
Dynamic tension , anyone ?
As the society goes into the Singularity , does it mean that you go into the mainstream or get washed up in one of the fractal tributaries ?
See parts of you on the other side
Fractally and partially yours
Andre
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Appendix I
The Origins of War and Peace
Andre Willers
20 April 2007
( see previous discussions in http://andreswhy.blogspot.com)
Synopsis :
War is when a society sanctions other humans as prey .
If the other humans belong to another society , it is Classical War . If not , it is a Police Action .
Endless fun is had by playing around with the definitions of “human” (Nazis) , “society” (religions , political movements , criminals , etc) .
Discussion:
Humans have a hard-wired brain center that classifies something as “prey” . Once this switch has tripped and the fixation has taken place , it is extremely difficult to change.
Evolutionary , it derived from pack-behaviour .
Pack hunters need to identify the chosen prey which the pack-leader has designated . The pointers derive from the leader’s social behaviour like pointing , eye-fixation , words etc .
Then they need to fixate on this prey to exclusion . (The nuts-and-bolts neuronal arrangement can be traced back to infant-imprinting.)
Successful packs are those that can focus the full pack on a particular prey , even if individual members of the pack might suffer injury or death .
A subsidiary hard-wired complex developed monitoring fellow-pack members . Any attack has to have some co-ordination . Call this Social-feeling .
Counting :
An iterative counting brain center that could count to three evolved .
(This center’s precise location has been identified (via fMRI). Rendering it inoperative (via magnetic focused pulse) led to a normally very rare inability to gut-feel numbers . Like reading by consulting a child’s primer every step .) Called anacalculus .
Us , Them ,Prey .
Each system is iteratively further broken down into threes , etc .
Three is necessary , since Us and Them is insufficient .
The Prey has to be identified , leading to Them being broken up into Them and Prey .
An intriguing corollary is that while the sets Us and Them may comprise many diverse elements , the Prey has to be constrained to one easily identified element . This explains why hate merchants like Hitler , the schoolyard bully , etc pick on specifics . Why neighbours who know each other kill neighbours in Uganda . Why the wife/husband is the most frequent unsanctioned homicidal victim .
There can only be One Prey .
(Apologies to the Highlander.)
Certain elements in martyr religions can be more easily understood this way .
Packs .
Packs are innate in any organism that cares for it’s young .
Parent(s) + kids = pack .
Iterative congeries across time of genetic relationships leads to complicated social relationships ( see inheritance of dominance in monkeys ,etc)
Human ancestors underwent a prolonged period of being cursorial raptors , developing pack behaviour on a genetic and social level to a high degree . This was convergent evolution with dogs . It is no wonder then that dogs and humans understand each other at such a deep , non-verbal level .
Parts of humans are the same as dogs .
Query : Why the insult of calling somebody a dog , a cur , a son-of-a-bitch etc ?
Answer : The insult is to the human being addressed , expressing dominance , not to dogs . In many cases , the only cultural referent understood by both human parties were doggish loyalty , which translated as slavishness between enemies . Indeed , many humans expressed their loyalty as being dogs of their ruler .
The dogs of war :
An interesting bit of propaganda by the Condottierri to put a spin on their faithless conduct .
Cannibalism .
Let’s face it , our ancestors ate each other until about 72 000 years ago .
The population density was low , making disease like kourou unlikely .
A large number of hominid evolutionary steps were driven by genetic deficiencies , necessitating obligate hunting . ( see previous discussions in http://andreswhy.blogspot.com)
Prey was everybody else except Us . This is the default Homonid setting .
MkI Homo Sapiens .
They evolved around 150 000 to 200 000 years ago .
The body was small by our standards , with little sexual dimorphism . The males were not much bigger , stronger or more aggressive than the females .
Great strength was not needed when hunting with weapons , snares and nets .
Indeed , big mass was selected against because of the significant higher energy needs that made starving to death much more likely during down-turns like droughts . Remember , there was little surplus and no way to store it .
Language was the main purview of the females . Gossiping and politics . The females were the central point of each group , together with the children . The males formed a cloud around this group . But arrangements were very loose and easy , as the living was easy .
Numbers were small , game was plentiful and other hominids made nice little packages of essential nutrients for these obligate hunters .
There is no culture as we even vaguely understand the term .
This was the end-line of development of pre-cultural homonins .
The default was that all not-Us were prey . ( Not War , not Peace , but anarchy)
MkII Homo Sapiens .
The Invention of Peace .
Then Toba happened . (72 000 BC )
The supervolcano in Indonesia caused the equivalent of a nuclear winter across the globe . Snow fell in equatorial regions and there was mass die-off of plants and their dependant animals .
The cold and hunger caused a concentration of numbers around some volcanic hotspots in the highlands of East Africa ( Remember , it snowed on the equator) . It did not happen all at once , so refugees fluxed into the survivable spots . In this crucible , human culture was invented . The numbers were small enough that certain existing epigenetic centers in the brain/body were forced evolved .
Remember , it took centuries for the land to recover .
From the genetic bottle-neck evidence , human numbers fell to between 3 000 and 10 000 . These are extinction levels
Cannibalistic diseases and inbreeding are particularly vicious in small , poorly nourished communities like these .
Co-operation and expansion of the gene-pool was essential .
The surviving communities were the ones where females took control and forced co-operation by designating non-prey .
In other words , the females ( probably led by some redoubtable dowager ) , invented Peace , and what’s more , enforced it .
This was Humanity’s greatest invention . The woman who did it deserves a Nobel prize for each year her Peace lasted .
Population was rigorously kept to sustainable levels by Matriarchal control of breeding lines and birthrates .
They did it so well that the Peace lasted about 60 000 years .
Note that the American and Australian continents where massive and quick animal extinctions took place , were populated from areas probably outside matriarchal control . Note also that the continent with the most extant animal megafauna (Africa) was where the matriarchy originated . Not too shabby ,eh?
One effect was thus the extreme taboo against cannibalism . This is an epigenetic inheritance ( ie data transmitted by mother to offspring , not in the DNA , but not cultural either .)
Inherent in this is that the Prey designation mechanism (now also epigenetic) came under social control . Elaborate rite-of-passage ceremonies evolved to certify an organism as human . (Failures were killed or expelled)
High on the list was Prey designation : hence the emphasis on starving candidates . The original rites featured humans as prey , and the candidate who could not control himself , failed .
This became putting off present gratification for future reward , what we think of as defining feature of cultural humans .
This also means the invention of religion , since the reward can be put off into the hereafter .
They also invented clothing , many uses of fire , hairdressing , makeup , jewelry , beads , gourmet cooking and the other things that make life worthwhile
Co-operating instead of hunting each other made trade and diversication of labour possible . Tools increased in sophistication from about 70 000 BC .
There was a significant human mutation in genes controlling brain growth . This has been very roughly dated as occurring about 40 000 – 50 000 years ago . The significance is not known , but it is speculated that it has to do with the growth of human culture .
The culture was explosively radiative . The advantages of a better and richer life through the material benefits sucked in even non-human homonins ( hence the gene mixing) . Anti-social elements were designated Prey and declared outlaw (this is what it means . The ultimate sanction then and now . Declared non-human , their only options were to die or to flee . )
When these MkII Humans exploded out of Africa , they did not kill the Neanderthals and Sinienses found in Europe and Asia . Their prey instincts were under social control .
Hence the interbreeding results now being found in the fossil record or the genetic evidence of the human flea .
( Some skeletons found indicate a mixture of Neanderthal and Homo Sapiens . Doubtlessly , more will be certain once the Neanderthal genome has been sequenced in about three years . More certain seems recent evidence of Siniens interbreeding , especially the genetic evidence that some species of human lice seemed to have crossed over back to Homo Sapiens from Siniens(Erectus) . The main-line Homo Sapiens fleas evolved into head and body lice after the invention of clothing after Toba .)
The other Sexes of Man
(see http://andreswhy.blogspot.com “The Sexes of Man”)
An intriguing speculation is that various null-sexes and homosexes got an evolutionary push from the reduced fertility in crossbreeding between MkII Homo and other various cousins that were subsumed into the Homo gene-cultural pool . This would have had a major effect on the evolution of the meme of property and inheritance .
MkII Humans .
What did they look like ?
The closest survivors we have are the Bushmen .
The female is the basic unit . There is little sexual dimorphism . The male is slightly larger than the female , but not significantly better muscled or more aggressive . Weapons and intelligence are more important in hunting than strength .
Females are the cultural guardians and control the group , both epigenetically and culturally .
Their Culture:
In fertile regions , the females and children form a nucleus with a floating cloud of males . Females select males to have children , either from personal taste or by direction of the Matriarchy . As expected , about 90% of males do not have children , as the females all select the alpha-males . This creates tension .
A Matriarchy .
Overpopulation was kept under check by infanticide of weaklings (bushmen , greeks , romans) . The limits of population were precisely known after literally tens of thousands of years of hunter-gatherer interactions .
An extremely stable form of government .
MkIII Homo Sapiens .
As can be seen from the above , the matriarchs naturally thought in terms of selective breeding . Hence their invention of agriculture and domesticated animals . (The were the finest genetic engineers the planet has yet seen , including the present poseurs.)
Yet the invention of both held the seeds of their destruction .
Domestication of animals and agriculture (circa 10 000 years ago) went hand-in-hand . Even today , most agricultural produce go to feed animals .
The net effect was a population explosion .
The old methods of estimating the carrying capacity of the land did not work with this new-fangled agriculture . The large groups of feral males expelled into the borderlands during the last 60 000 years now also increased in numbers due to end of the Ice-Age . They could be hired by surplus agricultural produce and promise of breeding women .
The matriarchs now had physical locations they had to defend against marauding clouds of feral males or males from other villages . Down-turns ( drought , winters , etc) made it worse . The inexorable logic of evolution means that no matter how many times you succeed , only one failure is enough to destroy you .
Increasing populations had led to population centers (cities) , that traded . Trade on this scale unleashed what we would call globalization . Cheaper produce and manufactures from the peripheries destroyed the livelihood of local farmers and artisans . The resulting social unrest necessitated breeding warriors from the outside stock to keep control for the oligarchy of matriarchs and priestesses .
This happened over a period of about 6 000 years . ( A Matriarchy is a really , really stable form of government .)
The result was an arms-race . The matriarchs either deliberately , or as a desperation measure , bred males for aggression and strength . This was easy in a culture that already practiced infanticide and death-by-neglect . Nubile females were directed only to mate with the jocks . Breeding stock was imported or required as tribute from the Outlands ( cf remnants like Theseus , etc)
The social structure (what we would call the Bronze Age) slowly broke down .
The Matriarchs also designated the competing groups as prey to their warrior clouds . War had arrived ..
MkIII Homo Sapiens was the result .
There is marked sexual dimorphism . The male is significantly bigger , but also grossly overpowered . Sinews and bones break continually from the overbred power .
The biggest difference is in aggression and Social-feeling . (see above)
There is a positive feedback between Aggression and Fellow-feeling . A large group focusing on a prey is more successful if the elements of the group share values more intensely . All we need to add is that large numbers of combatants are more successful than small numbers (generally true for low-energy weapons) , and you have an Army and War .
Social-Feeling:
The increase in social-feeling leads to large hysterical-type religions , and (not too put too fine a point on it ) large mobs .
The other whammy :
Horses .
Villages on the edges of the Ukrainian Steppes domesticated horses . Over hundreds of years , young men drifted into the steppes . Matriarchs could not follow them , since a pregnant woman cannot ride . The result was the formation of the Sky Gods religions . The horsemen turned around and made the originating villages their fiefs . From this basis they exploited every weakness of the Matriarchs .
Patriarchal religion arises .
The big Crack.
The collapse of the Late Bronze Age civilization (see http://andreswhy.blogspot.com)
This was not an overnight affair , but the later stages makes “Apocalypto” look like a picnic .
It was a combination of factors :
The breakdown of the social systems led to continual internecine warfare between city-states (ie groups of Matriarchs) . The males were being force-bred to be bigger and more aggressive . Then a climate shift caused a series of prolonged droughts from about 6 000 to 4 000 BC , seriously increasing unrest . The destruction of Minoan sea-power due to tsunamis and the inability to rebuild their fleet because they had denuded all readily accessible timber was the last straw . It took about 200 years , but the resultant spasm of war , destruction and cannibalism destroyed the matriarchies around the Middle-East and the Mediterranean .
The horse patriarchs swept over the remains and stamped patriarchal memes very firmly on the twitching remains .
Some Matriarchal memes remained in the far-west (Britain) . Hence the Druids .
Egypt and some surviving cities in the middle-east retained underground matriarchal cults ( Isis , Cybele , Earth Mother , etc , etc)
The Romans destroyed the corrupted Druid remnants .
The Roman Catholic Church later incorporated the main elements of the surviving matriarchy in the Roman Empire in the female saints and the Virgin Mary . The rest were ruthlessly exterminated . (Literally)
The only remnants of the Matriarchy that had ruled for nearly 70 000 years were some nunneries . Even here they were meme controlled ( Brides of Christ : ie connected to a male .)
Islam did the same . Note that the nun’s habit is identical with the chador .
It makes one wonder : why did the Council of Nicea decide on such a radical step ?
After all , the Roman Empire toward the end had little sex-discrimination . Constantinople had many empresses .
Why did the West suppress matriarchies ?
The suspicion arises that they did it because they felt threatened .
A meme structure like the Matriarchy that thinks in terms of 70 000 thousands of years and selective breeding of generations does not let a temporary hiatus of 5 000 years stop them . Indeed , elementary consideration would show that this could not have been the first or only reverse . Thus , they would have evolved mechanisms to survive what they consider temporary setbacks , together with some aggressive bounce-back mechanisms .
They probably tried to take over control of the Roman Catholic Church and the Western Empire . The Church destroyed most evidence , but there is Constantine’s mother , a taverners daughter who came up with some serious money to hire troops .
The killer , though , was probably the shenanigans with Attila . The Western Court at the time was even a bigger nest of snakes than usual . This was also the last time women played a significant role . If Aetius had not stopped Attila , the West would probably be a matriarchy now .
The Patriarchal meme-set seems to be long-lasting , but scared .
Some examples :
The refusal to aid Constantinople in 1453 . Indeed , the whole split . The West feels more comfortable with a patriarchal Islam than a matriarchy . Even so , Turkey seems to have been hit by a double whammy from the women : Naksh , and the enfolding and vanishment of the Circassians circa 1820 .
For those not up to speed :
Naksh (the Beautiful ) was a cousin of Josephine Bonaparte . They both came from Martinique and both became Empresses . Naksh was captured by Barbary pirates , and given as a virgin present to the Sultan . She must have been something exceptional , since he made her his principal and only wife , and more importantly , allowed her to educate her son the heir . This guy broke (well ,exterminated) the Janisseries (no mean feat) . He embarked the Ottoman Empire on the route that led to Turkey of today being a secular Islamic state (the only one) .
The Circassians were a tribe in the Caucasian mountains that reputedly for thousands of years bred their women for beauty and then sold them . This is like saying Elizabeth Taylor or Madonna is a slave . As you can imagine , even if it was not a matriarchal scheme to start off with , it would not be soon before the women ran the scheme . Reputedly , their beauty approached super-image quality , to such an extent that they had to be veiled so as not to drive men mad with visions of unattainability .
Of course the other side of the coin is more likely . For 60 000 years the matriarchy had bred and perfected women that could freeze men’s souls with their beauty and pheromones (cf Sirens , Circe , Gorgons , etc) . Brainy too . So the Circassians were breeding the beauty out , not in , to fit with modern society .
By 1820 they had to move , as the entire Caucasus mountains became very unsafe due to the Russian Empire expanding . Bullets or cannons do not care about beauty . The entire tribe moved to Constantinople and was not heard of again (of course) .
An interesting note here is that they probably had a copy of the Library of Constantinople . Very probably many of the originals . One of those ironies of history is that the Library everyone is looking for (including most of the Library of Alexandria) is right back where it started . A further ironic note is that Templars got obliterated mainly for having a copy . Contaminated by the Matriarchy . Fallout was the Albigensians and the Spanish Inquisition .
The question is : what on earth did the matriarchy do to provoke such an extreme response , one that has reverberated for thousands of years ? Even the memory of the deeds are gone (except maybe in some dusty archive) , but the emotions evoked still seem to be alive .
The only thing I can think of is a monstrous betrayal and perversion of the very bedrock of the Matriarchy’s social contract : when things got bad , they designated their people they considered useless as Prey and ate them .
This is like the Pope cutting out some nice fat American tourists on St Peter’s square and having a braai , with them as the guests of honour on the spit , all the while intoning that they should be honoured to serve .
Worse . Christianity has ritual cannibalism . No wonder this has reverberated down the ages . And it must have gone on for at least 200 years .
Shit . And I thought the high death rate in the Late Bronze age collapse was due to the quick conquest by the Sea Peoples . Instead , for hundreds of years the matriarchy and attendant nobles ate their people . The logic from their point is that the plebs should be honoured to feed their betters who know better and would be able to pull things together once the drought ends . And even when the drought ended , they could not stop . They were caught in the vested interests and , besides , it would take years before trade picked up and their shares paid a decent dividend .
The Sea Peoples were what we would call Liberators and Freedom Fighters . The capital letters are justified . Not even the Nazis or the Soviets ate the inmates of the camps , never mind put them in camps just for this purpose .
I always wondered how Rameses III could trust the Sea Peoples after the battle of the Nile to withdraw to southern Palestine . How could they exist if the area was so drought stricken ? But it wasn’t . It could support a lesser number , but not the overpopulated cities before . He had to promise to cleanse his country as well .Something he was not averse to .
But besides that , the Sea Peoples were fighting to cleanse the world of a great evil . The last holdout was in Egypt . They would have kept coming . All of them had family that was eaten .
This monumental blunder took place after the invention of agriculture , when overpopulation got out of control . I presume the present Matriarchy is determined not to make the same mistake . Overpopulation is once again out of control .
A note to the Matriarchy :
Kindly do not attempt to dispose of the surplus biomass through your stomach . It did not work too well 5 000 years ago . This time you will get crispies all round . The contract of 72 000 years ago is that either all pull through , or none do . Got it ?
The crucial Patriarchal meme:
No woman shall be without a connection with some male .
It does not matter if the male is a father , brother , husband ,son ,etc .
The intention is to prevent the build-up of a purely female powerbase . (ie a Matriarchy)
It worked for about 5 000 years .
Why it broke down :
The hidden assumption:
A high death rate due to high female death rate in childbirth .
This assumption steadily diverged from reality since about 1850 , as asepsis and birth procedures progressed .
The result was that woman outlived men by about 7 years on average . Rich woman in the US inheriting all their husband’s assets is a bigger percentage since the 1920’s . The US is a matriarchy by now .
Some symptoms:
Some 66% of US families have only one parent , namely the mother .
Crime rates have increased . This is because clouds of males are forming ,without matriarchal systems to keep them in control . At the levels of aggression and
testosterone the females have bred into them , only one thing will work :
UltraMama
A discreet word with Marvel Comics or some games designer might be appropriate .
And please , not SuperMama . Every Mama is a SuperMama .
MkIV Homo Sapiens .
Around 1800 the New Model Homo Saps was rolled out .
The new model is emotionally cool and is inclined to compulsive behaviour .
It welcomes uberbabes , but vehemently rejects a role as appetizer or even main course .
Aggression is not impulsive , but compulsive .
This is epigenetic .
This means that he can only be reasoned with . Emotional pressure points like fear , hate , love will play no role in behaviour .
Once an aggressive course is determined , nothing will stop it except superior force or logic .
The development of industrial technology required people that can concentrate for hours at a time on technical things like lathes , mathematics , etc , etc . The Fellow-feeling center in the brain suddenly became the cannon-fodder center .
A previous pathology ( Autism spectrum ) was dusted off and selection pressures are busily selecting and modifying . Aspergers (which did not exist before , suddenly is a desirable condition . The rough edges are being filed off .
It also means that the political control both Patriarchies and Matriarchies had is evaporating . The levers are turning to mush under their fingers .
Both have failed . They think the solution is in killing off their constituents when things get tough . This is no longer a viable solution from their viewpoint , as they have already lost control of the technical aspects . They are the most likely ones to do the tumbrel dance when things go ape .
Andre
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Appendix II
Hysterical Focus and Ostrum Commons
Andre Willers
20 Oct 2011
Synopsis :
Hysterical Foci spontaneously self-assemble if there are a critical number of Ostrum Commons Rules present .
There are Eight Ostrom Rules . General theory of Reserves suggest that any 1/3 of them (ie any 3 rules ) will lead to Self-assembly of an Hysterical Focus . Regardless of consequences .
Discussion :
1.Hysterical Focus :
See http://andreswhy.blogspot.com “Inside the ignition of an hysterical focus” Jun 2010
Humans are an hysterical species . This was turned into a powerful advantage .
It evolved from early monkey and ape stages .
The attention and energies of the whole troop is co-opted (ie involuntary) and co-ordinated onto one single subject . This happens in the amygdala and hippocampus .
Fast forward to humans , and you have fashion (a mild form) or an Hysterical Focus .
All the resources of the group is devoted to the problem in an involuntary fashion .
No human is immune .
Individual considerations are overridden at very deep levels .
The stuff Revolutions are made from .
A highly successful method of breaking false optimal peaks
2.Ostrum Commons :
The system formed a Commons , resolvable in three ways :
2.1Tragedy of the Commons (Communism) Cf Aral Sea
2.2Private ownership(Capitalism) Cf Economic crashes
2.3Ostrum Commons .
This lost out in competition because it is essentially a fractal Small-system , dependant on good communication . It kept bubbling up in peasant revolts , but could never self-cohere .
This changed with electronic communication systems like facebook , twitter, telephone ,etc .
Unstoppable now . Over a certain quantitive threshold , the network changes quantitively.
3.Self-Assembly :
Any three Ostrum rules present will result in the spontaneous self-assembly of the other Rules .
The Dear Reader can prove this himself/herself .(Hint:look at overlapping dimensionalities of the Rules)
Or they can cheat and look at http://andreswhy.blogspot.com “New Tools” Nov 2008 .
If there is a sufficient density of communication , an Hysterical Focus will form . And we are off to the races . A fertile field of future research .
4.Some interesting properties of Hysterical Foci :
4.1They don't stop . Once ignited , the Focus continues until the goals are met or the information links have been smashed (not possible today , even with a nuclear war). Hunkering down and waiting until it dies down does not work .
4.2There are no leaders initially . Decoying the structure into an hierarchical system has been an old counter . Not possible with a large number of alternate information pathways , or the awareness of Ostrum Rules .
4.3The individual members of the Hysterical Focus follow group rules , not self-interest .
Your old-fashioned Revolutionaries .
4.4Nobody is immune . It is as deep as your genes .
4.5Politicians , PR and advertising firms have become aware of the effect and are trying to harness it .
Sigh . It is a Beth(2) system , and it will always turn in their hands .
Hysterically yours
Andre
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Appendix A
A powerful example :
China :
http://en.wikipedia.org/wiki/Household-responsibility_system
History
Politicians did not initiate the household-responsibility system : local villagers developed it as an experiment later applied nationwide.
Allocating farmlands to individuals or to families rated as a crime during the Mao era in China, but the low-level productivity under collective farming and drought forced villagers ofXiaogang, Fengyang to do so in 1978. They implemented this system secretly, and signed a contract, "if any one of us is put to prison as a result, others shall be responsible for taking care of his children until they reach 18 years of age".
The secret experiment proved very successful. In 1979 similar experiments began inSichuan and Anhui provinces, both seeing dramatic increases in agricultural productivity.Deng Xiaoping openly praised these experiments in 1980, and the system has been adopted nationwide since 1981.
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Andre Willers
14 Nov 2012
“The Real Gates of Janus are closing”
Synopsis:
General War is becoming less prevalent as technology enables smart targeting of particular prey .
Discussion:
War results from the certain targets being designated as “prey” by social authorities .
See Appendix I for a further discussion . But this was written in 2007 . Things have changed . (A definition of the run-up into the Singularity . )
Prey are now designated by social media like Facebook and Twitter .
Very democratic and short-term .
But is there a long-term ?
Closing in on the Singularity , things change faster and faster . There is no long-term in any meaningful terms .
The Hysterical Focus :
Described in Appendix II . This is the mechanism whereby Prey is selected by the Social Organism . For examples see what happened to Gaddafi , Murdock , BBC etc . What is happening to Assad .
Notice there is no workable use of the Jingoism used before by ruling classes to divert attention into a General War . The fine detail of the social media makes this impossible .
What does this mean ?
It means that fighting does not cease , but it gets chopped up into smaller , manageable pieces , not large Wars .
These smaller pieces can be handled by the Ostrum Principles .
So , we are seeing a not so quiet revolution where everybody settles their differences on a small scale , and declines an invitation to a general conflagration .
The humans who actually create these dangerous toys decline to play any more .
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An interesting aside :
The sociopathic switch will be selected against . A lot of sociopaths will suddenly become kind and caring . (It is a epigenetic switch , not DNA . The chemicals are air-borne and touch .) . Won’t help much for psychopaths , but there might be some “spontaneous remission “ for some schizophrenics .
Kindness is in the air .
You can already see it in the hierarchical chiefs beating their breasts and saying “ Sorry”
Oh well . Lack of conscience works on a small scale as well . As long as the bastards do not get their hands on large levers of power .
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Summation :
“Plus la change”
The Matriarchy has won on Earth . But the off-Earth systems are the equivalent of the horse-nomads
And so it repeats .
I thought it would mercifully end with extinction of humans about 2060 AD , but space-nomads and the Matriarchy seems to be God’s little joke .
Singularity only for some .
The Singularities will follow Riemann’s Expansion , if only you knew the dimensions .
Dynamic tension , anyone ?
As the society goes into the Singularity , does it mean that you go into the mainstream or get washed up in one of the fractal tributaries ?
See parts of you on the other side
Fractally and partially yours
Andre
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Appendix I
The Origins of War and Peace
Andre Willers
20 April 2007
( see previous discussions in http://andreswhy.blogspot.com)
Synopsis :
War is when a society sanctions other humans as prey .
If the other humans belong to another society , it is Classical War . If not , it is a Police Action .
Endless fun is had by playing around with the definitions of “human” (Nazis) , “society” (religions , political movements , criminals , etc) .
Discussion:
Humans have a hard-wired brain center that classifies something as “prey” . Once this switch has tripped and the fixation has taken place , it is extremely difficult to change.
Evolutionary , it derived from pack-behaviour .
Pack hunters need to identify the chosen prey which the pack-leader has designated . The pointers derive from the leader’s social behaviour like pointing , eye-fixation , words etc .
Then they need to fixate on this prey to exclusion . (The nuts-and-bolts neuronal arrangement can be traced back to infant-imprinting.)
Successful packs are those that can focus the full pack on a particular prey , even if individual members of the pack might suffer injury or death .
A subsidiary hard-wired complex developed monitoring fellow-pack members . Any attack has to have some co-ordination . Call this Social-feeling .
Counting :
An iterative counting brain center that could count to three evolved .
(This center’s precise location has been identified (via fMRI). Rendering it inoperative (via magnetic focused pulse) led to a normally very rare inability to gut-feel numbers . Like reading by consulting a child’s primer every step .) Called anacalculus .
Us , Them ,Prey .
Each system is iteratively further broken down into threes , etc .
Three is necessary , since Us and Them is insufficient .
The Prey has to be identified , leading to Them being broken up into Them and Prey .
An intriguing corollary is that while the sets Us and Them may comprise many diverse elements , the Prey has to be constrained to one easily identified element . This explains why hate merchants like Hitler , the schoolyard bully , etc pick on specifics . Why neighbours who know each other kill neighbours in Uganda . Why the wife/husband is the most frequent unsanctioned homicidal victim .
There can only be One Prey .
(Apologies to the Highlander.)
Certain elements in martyr religions can be more easily understood this way .
Packs .
Packs are innate in any organism that cares for it’s young .
Parent(s) + kids = pack .
Iterative congeries across time of genetic relationships leads to complicated social relationships ( see inheritance of dominance in monkeys ,etc)
Human ancestors underwent a prolonged period of being cursorial raptors , developing pack behaviour on a genetic and social level to a high degree . This was convergent evolution with dogs . It is no wonder then that dogs and humans understand each other at such a deep , non-verbal level .
Parts of humans are the same as dogs .
Query : Why the insult of calling somebody a dog , a cur , a son-of-a-bitch etc ?
Answer : The insult is to the human being addressed , expressing dominance , not to dogs . In many cases , the only cultural referent understood by both human parties were doggish loyalty , which translated as slavishness between enemies . Indeed , many humans expressed their loyalty as being dogs of their ruler .
The dogs of war :
An interesting bit of propaganda by the Condottierri to put a spin on their faithless conduct .
Cannibalism .
Let’s face it , our ancestors ate each other until about 72 000 years ago .
The population density was low , making disease like kourou unlikely .
A large number of hominid evolutionary steps were driven by genetic deficiencies , necessitating obligate hunting . ( see previous discussions in http://andreswhy.blogspot.com)
Prey was everybody else except Us . This is the default Homonid setting .
MkI Homo Sapiens .
They evolved around 150 000 to 200 000 years ago .
The body was small by our standards , with little sexual dimorphism . The males were not much bigger , stronger or more aggressive than the females .
Great strength was not needed when hunting with weapons , snares and nets .
Indeed , big mass was selected against because of the significant higher energy needs that made starving to death much more likely during down-turns like droughts . Remember , there was little surplus and no way to store it .
Language was the main purview of the females . Gossiping and politics . The females were the central point of each group , together with the children . The males formed a cloud around this group . But arrangements were very loose and easy , as the living was easy .
Numbers were small , game was plentiful and other hominids made nice little packages of essential nutrients for these obligate hunters .
There is no culture as we even vaguely understand the term .
This was the end-line of development of pre-cultural homonins .
The default was that all not-Us were prey . ( Not War , not Peace , but anarchy)
MkII Homo Sapiens .
The Invention of Peace .
Then Toba happened . (72 000 BC )
The supervolcano in Indonesia caused the equivalent of a nuclear winter across the globe . Snow fell in equatorial regions and there was mass die-off of plants and their dependant animals .
The cold and hunger caused a concentration of numbers around some volcanic hotspots in the highlands of East Africa ( Remember , it snowed on the equator) . It did not happen all at once , so refugees fluxed into the survivable spots . In this crucible , human culture was invented . The numbers were small enough that certain existing epigenetic centers in the brain/body were forced evolved .
Remember , it took centuries for the land to recover .
From the genetic bottle-neck evidence , human numbers fell to between 3 000 and 10 000 . These are extinction levels
Cannibalistic diseases and inbreeding are particularly vicious in small , poorly nourished communities like these .
Co-operation and expansion of the gene-pool was essential .
The surviving communities were the ones where females took control and forced co-operation by designating non-prey .
In other words , the females ( probably led by some redoubtable dowager ) , invented Peace , and what’s more , enforced it .
This was Humanity’s greatest invention . The woman who did it deserves a Nobel prize for each year her Peace lasted .
Population was rigorously kept to sustainable levels by Matriarchal control of breeding lines and birthrates .
They did it so well that the Peace lasted about 60 000 years .
Note that the American and Australian continents where massive and quick animal extinctions took place , were populated from areas probably outside matriarchal control . Note also that the continent with the most extant animal megafauna (Africa) was where the matriarchy originated . Not too shabby ,eh?
One effect was thus the extreme taboo against cannibalism . This is an epigenetic inheritance ( ie data transmitted by mother to offspring , not in the DNA , but not cultural either .)
Inherent in this is that the Prey designation mechanism (now also epigenetic) came under social control . Elaborate rite-of-passage ceremonies evolved to certify an organism as human . (Failures were killed or expelled)
High on the list was Prey designation : hence the emphasis on starving candidates . The original rites featured humans as prey , and the candidate who could not control himself , failed .
This became putting off present gratification for future reward , what we think of as defining feature of cultural humans .
This also means the invention of religion , since the reward can be put off into the hereafter .
They also invented clothing , many uses of fire , hairdressing , makeup , jewelry , beads , gourmet cooking and the other things that make life worthwhile
Co-operating instead of hunting each other made trade and diversication of labour possible . Tools increased in sophistication from about 70 000 BC .
There was a significant human mutation in genes controlling brain growth . This has been very roughly dated as occurring about 40 000 – 50 000 years ago . The significance is not known , but it is speculated that it has to do with the growth of human culture .
The culture was explosively radiative . The advantages of a better and richer life through the material benefits sucked in even non-human homonins ( hence the gene mixing) . Anti-social elements were designated Prey and declared outlaw (this is what it means . The ultimate sanction then and now . Declared non-human , their only options were to die or to flee . )
When these MkII Humans exploded out of Africa , they did not kill the Neanderthals and Sinienses found in Europe and Asia . Their prey instincts were under social control .
Hence the interbreeding results now being found in the fossil record or the genetic evidence of the human flea .
( Some skeletons found indicate a mixture of Neanderthal and Homo Sapiens . Doubtlessly , more will be certain once the Neanderthal genome has been sequenced in about three years . More certain seems recent evidence of Siniens interbreeding , especially the genetic evidence that some species of human lice seemed to have crossed over back to Homo Sapiens from Siniens(Erectus) . The main-line Homo Sapiens fleas evolved into head and body lice after the invention of clothing after Toba .)
The other Sexes of Man
(see http://andreswhy.blogspot.com “The Sexes of Man”)
An intriguing speculation is that various null-sexes and homosexes got an evolutionary push from the reduced fertility in crossbreeding between MkII Homo and other various cousins that were subsumed into the Homo gene-cultural pool . This would have had a major effect on the evolution of the meme of property and inheritance .
MkII Humans .
What did they look like ?
The closest survivors we have are the Bushmen .
The female is the basic unit . There is little sexual dimorphism . The male is slightly larger than the female , but not significantly better muscled or more aggressive . Weapons and intelligence are more important in hunting than strength .
Females are the cultural guardians and control the group , both epigenetically and culturally .
Their Culture:
In fertile regions , the females and children form a nucleus with a floating cloud of males . Females select males to have children , either from personal taste or by direction of the Matriarchy . As expected , about 90% of males do not have children , as the females all select the alpha-males . This creates tension .
A Matriarchy .
Overpopulation was kept under check by infanticide of weaklings (bushmen , greeks , romans) . The limits of population were precisely known after literally tens of thousands of years of hunter-gatherer interactions .
An extremely stable form of government .
MkIII Homo Sapiens .
As can be seen from the above , the matriarchs naturally thought in terms of selective breeding . Hence their invention of agriculture and domesticated animals . (The were the finest genetic engineers the planet has yet seen , including the present poseurs.)
Yet the invention of both held the seeds of their destruction .
Domestication of animals and agriculture (circa 10 000 years ago) went hand-in-hand . Even today , most agricultural produce go to feed animals .
The net effect was a population explosion .
The old methods of estimating the carrying capacity of the land did not work with this new-fangled agriculture . The large groups of feral males expelled into the borderlands during the last 60 000 years now also increased in numbers due to end of the Ice-Age . They could be hired by surplus agricultural produce and promise of breeding women .
The matriarchs now had physical locations they had to defend against marauding clouds of feral males or males from other villages . Down-turns ( drought , winters , etc) made it worse . The inexorable logic of evolution means that no matter how many times you succeed , only one failure is enough to destroy you .
Increasing populations had led to population centers (cities) , that traded . Trade on this scale unleashed what we would call globalization . Cheaper produce and manufactures from the peripheries destroyed the livelihood of local farmers and artisans . The resulting social unrest necessitated breeding warriors from the outside stock to keep control for the oligarchy of matriarchs and priestesses .
This happened over a period of about 6 000 years . ( A Matriarchy is a really , really stable form of government .)
The result was an arms-race . The matriarchs either deliberately , or as a desperation measure , bred males for aggression and strength . This was easy in a culture that already practiced infanticide and death-by-neglect . Nubile females were directed only to mate with the jocks . Breeding stock was imported or required as tribute from the Outlands ( cf remnants like Theseus , etc)
The social structure (what we would call the Bronze Age) slowly broke down .
The Matriarchs also designated the competing groups as prey to their warrior clouds . War had arrived ..
MkIII Homo Sapiens was the result .
There is marked sexual dimorphism . The male is significantly bigger , but also grossly overpowered . Sinews and bones break continually from the overbred power .
The biggest difference is in aggression and Social-feeling . (see above)
There is a positive feedback between Aggression and Fellow-feeling . A large group focusing on a prey is more successful if the elements of the group share values more intensely . All we need to add is that large numbers of combatants are more successful than small numbers (generally true for low-energy weapons) , and you have an Army and War .
Social-Feeling:
The increase in social-feeling leads to large hysterical-type religions , and (not too put too fine a point on it ) large mobs .
The other whammy :
Horses .
Villages on the edges of the Ukrainian Steppes domesticated horses . Over hundreds of years , young men drifted into the steppes . Matriarchs could not follow them , since a pregnant woman cannot ride . The result was the formation of the Sky Gods religions . The horsemen turned around and made the originating villages their fiefs . From this basis they exploited every weakness of the Matriarchs .
Patriarchal religion arises .
The big Crack.
The collapse of the Late Bronze Age civilization (see http://andreswhy.blogspot.com)
This was not an overnight affair , but the later stages makes “Apocalypto” look like a picnic .
It was a combination of factors :
The breakdown of the social systems led to continual internecine warfare between city-states (ie groups of Matriarchs) . The males were being force-bred to be bigger and more aggressive . Then a climate shift caused a series of prolonged droughts from about 6 000 to 4 000 BC , seriously increasing unrest . The destruction of Minoan sea-power due to tsunamis and the inability to rebuild their fleet because they had denuded all readily accessible timber was the last straw . It took about 200 years , but the resultant spasm of war , destruction and cannibalism destroyed the matriarchies around the Middle-East and the Mediterranean .
The horse patriarchs swept over the remains and stamped patriarchal memes very firmly on the twitching remains .
Some Matriarchal memes remained in the far-west (Britain) . Hence the Druids .
Egypt and some surviving cities in the middle-east retained underground matriarchal cults ( Isis , Cybele , Earth Mother , etc , etc)
The Romans destroyed the corrupted Druid remnants .
The Roman Catholic Church later incorporated the main elements of the surviving matriarchy in the Roman Empire in the female saints and the Virgin Mary . The rest were ruthlessly exterminated . (Literally)
The only remnants of the Matriarchy that had ruled for nearly 70 000 years were some nunneries . Even here they were meme controlled ( Brides of Christ : ie connected to a male .)
Islam did the same . Note that the nun’s habit is identical with the chador .
It makes one wonder : why did the Council of Nicea decide on such a radical step ?
After all , the Roman Empire toward the end had little sex-discrimination . Constantinople had many empresses .
Why did the West suppress matriarchies ?
The suspicion arises that they did it because they felt threatened .
A meme structure like the Matriarchy that thinks in terms of 70 000 thousands of years and selective breeding of generations does not let a temporary hiatus of 5 000 years stop them . Indeed , elementary consideration would show that this could not have been the first or only reverse . Thus , they would have evolved mechanisms to survive what they consider temporary setbacks , together with some aggressive bounce-back mechanisms .
They probably tried to take over control of the Roman Catholic Church and the Western Empire . The Church destroyed most evidence , but there is Constantine’s mother , a taverners daughter who came up with some serious money to hire troops .
The killer , though , was probably the shenanigans with Attila . The Western Court at the time was even a bigger nest of snakes than usual . This was also the last time women played a significant role . If Aetius had not stopped Attila , the West would probably be a matriarchy now .
The Patriarchal meme-set seems to be long-lasting , but scared .
Some examples :
The refusal to aid Constantinople in 1453 . Indeed , the whole split . The West feels more comfortable with a patriarchal Islam than a matriarchy . Even so , Turkey seems to have been hit by a double whammy from the women : Naksh , and the enfolding and vanishment of the Circassians circa 1820 .
For those not up to speed :
Naksh (the Beautiful ) was a cousin of Josephine Bonaparte . They both came from Martinique and both became Empresses . Naksh was captured by Barbary pirates , and given as a virgin present to the Sultan . She must have been something exceptional , since he made her his principal and only wife , and more importantly , allowed her to educate her son the heir . This guy broke (well ,exterminated) the Janisseries (no mean feat) . He embarked the Ottoman Empire on the route that led to Turkey of today being a secular Islamic state (the only one) .
The Circassians were a tribe in the Caucasian mountains that reputedly for thousands of years bred their women for beauty and then sold them . This is like saying Elizabeth Taylor or Madonna is a slave . As you can imagine , even if it was not a matriarchal scheme to start off with , it would not be soon before the women ran the scheme . Reputedly , their beauty approached super-image quality , to such an extent that they had to be veiled so as not to drive men mad with visions of unattainability .
Of course the other side of the coin is more likely . For 60 000 years the matriarchy had bred and perfected women that could freeze men’s souls with their beauty and pheromones (cf Sirens , Circe , Gorgons , etc) . Brainy too . So the Circassians were breeding the beauty out , not in , to fit with modern society .
By 1820 they had to move , as the entire Caucasus mountains became very unsafe due to the Russian Empire expanding . Bullets or cannons do not care about beauty . The entire tribe moved to Constantinople and was not heard of again (of course) .
An interesting note here is that they probably had a copy of the Library of Constantinople . Very probably many of the originals . One of those ironies of history is that the Library everyone is looking for (including most of the Library of Alexandria) is right back where it started . A further ironic note is that Templars got obliterated mainly for having a copy . Contaminated by the Matriarchy . Fallout was the Albigensians and the Spanish Inquisition .
The question is : what on earth did the matriarchy do to provoke such an extreme response , one that has reverberated for thousands of years ? Even the memory of the deeds are gone (except maybe in some dusty archive) , but the emotions evoked still seem to be alive .
The only thing I can think of is a monstrous betrayal and perversion of the very bedrock of the Matriarchy’s social contract : when things got bad , they designated their people they considered useless as Prey and ate them .
This is like the Pope cutting out some nice fat American tourists on St Peter’s square and having a braai , with them as the guests of honour on the spit , all the while intoning that they should be honoured to serve .
Worse . Christianity has ritual cannibalism . No wonder this has reverberated down the ages . And it must have gone on for at least 200 years .
Shit . And I thought the high death rate in the Late Bronze age collapse was due to the quick conquest by the Sea Peoples . Instead , for hundreds of years the matriarchy and attendant nobles ate their people . The logic from their point is that the plebs should be honoured to feed their betters who know better and would be able to pull things together once the drought ends . And even when the drought ended , they could not stop . They were caught in the vested interests and , besides , it would take years before trade picked up and their shares paid a decent dividend .
The Sea Peoples were what we would call Liberators and Freedom Fighters . The capital letters are justified . Not even the Nazis or the Soviets ate the inmates of the camps , never mind put them in camps just for this purpose .
I always wondered how Rameses III could trust the Sea Peoples after the battle of the Nile to withdraw to southern Palestine . How could they exist if the area was so drought stricken ? But it wasn’t . It could support a lesser number , but not the overpopulated cities before . He had to promise to cleanse his country as well .Something he was not averse to .
But besides that , the Sea Peoples were fighting to cleanse the world of a great evil . The last holdout was in Egypt . They would have kept coming . All of them had family that was eaten .
This monumental blunder took place after the invention of agriculture , when overpopulation got out of control . I presume the present Matriarchy is determined not to make the same mistake . Overpopulation is once again out of control .
A note to the Matriarchy :
Kindly do not attempt to dispose of the surplus biomass through your stomach . It did not work too well 5 000 years ago . This time you will get crispies all round . The contract of 72 000 years ago is that either all pull through , or none do . Got it ?
The crucial Patriarchal meme:
No woman shall be without a connection with some male .
It does not matter if the male is a father , brother , husband ,son ,etc .
The intention is to prevent the build-up of a purely female powerbase . (ie a Matriarchy)
It worked for about 5 000 years .
Why it broke down :
The hidden assumption:
A high death rate due to high female death rate in childbirth .
This assumption steadily diverged from reality since about 1850 , as asepsis and birth procedures progressed .
The result was that woman outlived men by about 7 years on average . Rich woman in the US inheriting all their husband’s assets is a bigger percentage since the 1920’s . The US is a matriarchy by now .
Some symptoms:
Some 66% of US families have only one parent , namely the mother .
Crime rates have increased . This is because clouds of males are forming ,without matriarchal systems to keep them in control . At the levels of aggression and
testosterone the females have bred into them , only one thing will work :
UltraMama
A discreet word with Marvel Comics or some games designer might be appropriate .
And please , not SuperMama . Every Mama is a SuperMama .
MkIV Homo Sapiens .
Around 1800 the New Model Homo Saps was rolled out .
The new model is emotionally cool and is inclined to compulsive behaviour .
It welcomes uberbabes , but vehemently rejects a role as appetizer or even main course .
Aggression is not impulsive , but compulsive .
This is epigenetic .
This means that he can only be reasoned with . Emotional pressure points like fear , hate , love will play no role in behaviour .
Once an aggressive course is determined , nothing will stop it except superior force or logic .
The development of industrial technology required people that can concentrate for hours at a time on technical things like lathes , mathematics , etc , etc . The Fellow-feeling center in the brain suddenly became the cannon-fodder center .
A previous pathology ( Autism spectrum ) was dusted off and selection pressures are busily selecting and modifying . Aspergers (which did not exist before , suddenly is a desirable condition . The rough edges are being filed off .
It also means that the political control both Patriarchies and Matriarchies had is evaporating . The levers are turning to mush under their fingers .
Both have failed . They think the solution is in killing off their constituents when things get tough . This is no longer a viable solution from their viewpoint , as they have already lost control of the technical aspects . They are the most likely ones to do the tumbrel dance when things go ape .
Andre
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Appendix II
Hysterical Focus and Ostrum Commons
Andre Willers
20 Oct 2011
Synopsis :
Hysterical Foci spontaneously self-assemble if there are a critical number of Ostrum Commons Rules present .
There are Eight Ostrom Rules . General theory of Reserves suggest that any 1/3 of them (ie any 3 rules ) will lead to Self-assembly of an Hysterical Focus . Regardless of consequences .
Discussion :
1.Hysterical Focus :
See http://andreswhy.blogspot.com “Inside the ignition of an hysterical focus” Jun 2010
Humans are an hysterical species . This was turned into a powerful advantage .
It evolved from early monkey and ape stages .
The attention and energies of the whole troop is co-opted (ie involuntary) and co-ordinated onto one single subject . This happens in the amygdala and hippocampus .
Fast forward to humans , and you have fashion (a mild form) or an Hysterical Focus .
All the resources of the group is devoted to the problem in an involuntary fashion .
No human is immune .
Individual considerations are overridden at very deep levels .
The stuff Revolutions are made from .
A highly successful method of breaking false optimal peaks
2.Ostrum Commons :
The system formed a Commons , resolvable in three ways :
2.1Tragedy of the Commons (Communism) Cf Aral Sea
2.2Private ownership(Capitalism) Cf Economic crashes
2.3Ostrum Commons .
This lost out in competition because it is essentially a fractal Small-system , dependant on good communication . It kept bubbling up in peasant revolts , but could never self-cohere .
This changed with electronic communication systems like facebook , twitter, telephone ,etc .
Unstoppable now . Over a certain quantitive threshold , the network changes quantitively.
3.Self-Assembly :
Any three Ostrum rules present will result in the spontaneous self-assembly of the other Rules .
The Dear Reader can prove this himself/herself .(Hint:look at overlapping dimensionalities of the Rules)
Or they can cheat and look at http://andreswhy.blogspot.com “New Tools” Nov 2008 .
If there is a sufficient density of communication , an Hysterical Focus will form . And we are off to the races . A fertile field of future research .
4.Some interesting properties of Hysterical Foci :
4.1They don't stop . Once ignited , the Focus continues until the goals are met or the information links have been smashed (not possible today , even with a nuclear war). Hunkering down and waiting until it dies down does not work .
4.2There are no leaders initially . Decoying the structure into an hierarchical system has been an old counter . Not possible with a large number of alternate information pathways , or the awareness of Ostrum Rules .
4.3The individual members of the Hysterical Focus follow group rules , not self-interest .
Your old-fashioned Revolutionaries .
4.4Nobody is immune . It is as deep as your genes .
4.5Politicians , PR and advertising firms have become aware of the effect and are trying to harness it .
Sigh . It is a Beth(2) system , and it will always turn in their hands .
Hysterically yours
Andre
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Appendix A
A powerful example :
China :
http://en.wikipedia.org/wiki/Household-responsibility_system
History
Politicians did not initiate the household-responsibility system : local villagers developed it as an experiment later applied nationwide.
Allocating farmlands to individuals or to families rated as a crime during the Mao era in China, but the low-level productivity under collective farming and drought forced villagers ofXiaogang, Fengyang to do so in 1978. They implemented this system secretly, and signed a contract, "if any one of us is put to prison as a result, others shall be responsible for taking care of his children until they reach 18 years of age".
The secret experiment proved very successful. In 1979 similar experiments began inSichuan and Anhui provinces, both seeing dramatic increases in agricultural productivity.Deng Xiaoping openly praised these experiments in 1980, and the system has been adopted nationwide since 1981.
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