Peripheral Neuropathy of Legs. A Cure.

Peripheral Neuropathy of Legs. A Cure.
Andre Willers
20 Apr 2010

My Birthday Present to fellow sufferers .

Synopsis:
A methodology for reducing chronic symptoms (95%) and repairing nerves .

Summary:
Data from my personal experience .
1.Use APS as for lower back pain once a day (8 min) . Unease relief 80%-85% .
2.Use capsaicum on upper thighs . Before sleep . Unease relief 10% . The need for this will decrease after about 5-7 usages of APS usage .
3. Keep blood-glucose concentration <=6.5
4. Do not eat high acrylamide foods
5.Take alpha-lipoic acid . 250 mg (1+2+1) per day initially .Taper .
Beware reflux . An amusing side effect . Rejection reflexes of crap food are repaired .
Not beloved by the fast-food industry .
(Pregnant women should not take this in large doses. )

Discussion :
The pathology is caused by damage to the nerves , (especially the long leg-nerves) by high glucose concentrations in DiabetesII and Acrylamide from diet .

How it works:
The pain-pulses of damaged nerve A arrive at the synapses in the lower back (spine) . Here , certain specialized glial cells count the frequency and duration . To prevent the gate-effect of pain impulses to mask further pain signals of further tissue damage from other nerves , these cells take on the function of automatically pulsing pain signals as if from nerve A , while inhibiting the damaged nerve A's signal .

This enables other damage signals to come through , preventing further damage .
This has obvious evolutionary advantages in preventing cascading damages .

The problem is that , even if damage to nerve A has been repaired , the off-switch of this mechanism may not work . Or the damage to nerve A might remain .

See http://andreswhy.blogspot.com "Peripheral Neuropathy" et al .
Chronic neuropathy results from the inability to activate the "Off" switch in microglial and astrocyte bodies in the dorsal root ganglion .
See Scientific American Nov 2009 p 33 .

A further teensy problem is that , even if there was a temporary repair , if the chronic condition (like too high glucose or acrylamide concentrations) the microglial and astrocyte bodies get re-triggered . And they would be sensitized as well .


The Methodology :
1.Drastically reduce the pain impulses from the microglial and astrocyte bodies in the dorsal root ganglion . For this we use the APS technology , with electrodes configured for "Back Pain" .
See www.apstherapy.com
See http://andreswhy.blogspot.com "ATP as Neurotransmitter"

I originally bought this machine in 2001 for Neuropathy leg pains , but put the electrodes on the legs . This had little or no effect . Only after reading the article :
See Scientific American Nov 2009 p 33 did I realize that the chronic pain is generated in the lower back .
Putting the electrodes on the sides of the lower hip as recommended for lower back pain led to a reduction of that chronic burning unease sensation of 80-85 percent.
After about 4-7 days .

Some of the remainder of unease could be ameliorated by using gate-theory : capsaicum . Just smear it on the thighs . This generates pain signals that compete at the lowest spine ganglia , but unfortunately the system habituates easily . .

This brings us to about 95% of unease .

At least I could sleep without analgesics .

But there are still twinges .

The damage to the nerves still exist . The neuropathic pain will quickly re-establish itself . We are just managing the condition , not curing it .

The Cure :
Repair the nerves , while keeping the damaging agents under control .
The damaging agents are too high concentrations of glucose and acrylamide .
Keep them under control via diet or insulin .

The repair is enhanced by alpha-lipoic acid (evening primrose oil).
Take supplements .

Desensitizing the system :
A really permanent , buffered system . I do not have that .
Working ,working ….

A promising lead is propranolol . Reprogramming memories at synapse level (ie the microglial and astrocyte bodies in the dorsal root ganglion .)
Google "propranolol PTSD"

Happy Birthday !

Andre