8 Dec 2007
AttentionDeficitDisorder (see previous post)
Biologically active sulfur for the skin
Essential Fatty Acids
I hereby give the overview and sources not mentioned in the previous post on AttentionDeficitDisorder .
An excellent overview given in November 2007 issue of Scientific American “ Cell Defenses : Sunshine Vitamin”
“1,25 diHydroxyvitaminD3 is a direct inducer ofAntimicrobial Peptide Gene Expression” by Wang et al Journal of Immunology vol 173 p2909-2913,2004
“The Pleiotropic actions of vitaminD” Lin BioEssays Vol26 .p649 March 2004
“Vitamin deficiency” by Holick “New England Journal of Medicine , Vol357,no3,p266-281.july 19,2007.
Biologically active sulphur .
I have discussed this before . It is sufficient to note that animals whose skins we want to use for things like shoes and furs , need additional supplements of sulphur to be usable . (Google “MSM animal feeds”)
This means that humans are also deficient in biologically active sulphur .
Sulphur is essential in the normal deployment of skin organelles .There is a synergistic effect .
The less sulphur , the less Vit D.
Cheap clothing and urbanization means that most humans only expose a small part of their body for small periods to UVB . A general shortage of sulphur exacerbates the effect , as the skin cannot function optimally .
The net effect is a chronic shortage of Vitamin D .
In Utero effects:
Switching on and off of genes are especially important during gestation . If there is general shortage of 1,25D during this period , the available supplies are switched to the most important systems . (This is a very ancient system) . Certain later genes do not get switched on . This leads to immune problems . Notice the dominant effect of VitD vs Folic Acid .
Can this be rectified?
Yes . During growth spurts . The puberty+ stage is important .
As discussed before , AttentionDeficitDisorder and HyperActivity is not only normal in the spurt of growth in neuromass after puberty , but essential . Every human goes through this stage .
Northern latitude Europeans used to have a cheap source of VitD and Essential Fatty Acids in oily fish . They have destroyed these fish stocks and are now paying the price .
The problem is not only an on-going shortage of 1,25D , but an accumulated shortage of gene switches which did not happen .
Which is why there is an upper limit to VitD dosages . Too much , and the accumulated by-products of long-delayed gene-switch-on’s poisens the organism .
Why do these delays build up ? Because these steps are essential in maturing sperm and ova cells . The corrollary is , of course , that fertility rates in far northern latitudes are very low . This is borne out by evidence (Laps , Mongols , Esquimeaux,etc)
Actual Case study:
A male youth entering puberty with symptoms of chronic VitD deficiency .
Certain gene-sets do not switch on (extended neotony) . This is observed as babylike behaviour: hyperactivity and inability to concentrate for long periods .
Puberty makes this much worse .
Available resources of VitD , Essential fatty acids and Sulphur are stretched to breaking point by development imperatives .
Intervention is simply making these building blocks available.
The dosages :
Sulphur is critical . Cells divide ,especially brain and muscle-cells .
Give a lot of MSM : 10 gm /day
VitD uptake will be enhanced , if sunshine exposure of about ½ hr per day is followed . You will tan rapidly and skin will be smooth .
If this is not possible , supplementations should be done . But note upper limit .
Essential fatty acids : the building blocks of the brain . Two tablespoons of flaxseedoil and codliveroil a day
If you plan lots of MSM and sunshine , be sure to include antioxidants .Make sure the exposure is logarithmic : a little at the start , then increasing rapidly . You will notice that you tan more rapidly (1/2 hr instead of days) . You are also more sane . (Less unstable)
Pak protector .
A theoretical construct by Larry Niven . Also known as grandmothers .The genetic effect is real .
Surviving Grandmothers are all Pak protectors to some degree .
Grandmothers like fish (all the ones I know) . Essential fatty acids etc .
Adding megadoses should be interesting .
Pak protectors on the female line are well known and real . But are there male Pak protectors ? We know that it would be an ancient system . The females groom the male into being the Pak protector . The effect is real . The male lives longer and is dominant . But the females are also caught in the same trap .The planet might have only one male Pak protector , and millions of female Pak protectors . Yet the females cannot co-ordinate without a nominal hierarchical head .
Any male can declare himself Pak protector . This has not been done for about 4 000 years . Interesting times indeed .
The Grandmother Party can indeed sweep the planet .
Who , after all , keeps the whole shebang together?
A toast to the Pak Party .