Sunday, June 03, 2012

Attention Deficit Disorder (ADD) Update

Attention Deficit Disorder (ADD) Update
Andre Willers
3 Jun 2012
“Nothing concentrates the mind like a sneeze”
Synopsis :
ADD is largely a deficiency disease , caused by Vit D , Sulfur and Omega 3 deficiencies . Once established as an amygdala pattern , it is difficult to correct .
Discussion :
This is not medical advice . Consult your qualified medical practitioner .

1.Vit D et al : see Appendix IV below , repeated for your ease .
2.Sulfur and Omega 3 : chemical bricks in insufficient concentrations in present diets . See previous posts ad nauseam .
3. ADD and Diabetes :
See http://andreswhy.blogspot.com “Cure for diabetes” May 2010 . (I am not going to repeat it here)
ADD is simply another cluster of ways in which the control systems fail because of overstretch .
Briefly:
4.Evolutionary control systems .
See http://en.wikipedia.org/wiki/Network_topology
Evolution normally proceeds in small adaptations of existing structures .
Thus a Tree-topology results . If something goes wrong in the branch close to the trunk , all subsequent structures flowing from that branch go wrong . The symptoms at the ends of the various twigs are usually very diverse and very difficult to diagnose . But there is a single root cause .
When the control systems become unstable , they collapse in literally trillions of different ways . A trap-door function . See http://andreswhy.blogspot.com “Cure for diabetes” May 2012 .
These dysfunctions look like clusters of symptoms (ie Syndromes or Diseases) viewed from the top .

ADD can thus be seen as but another cluster of symptoms as a result of Diabetes .
Adding Precursor chemicals means these chemicals just after the catastrophic break .
Things have to be fixed as close to the root-trunk as possible .
See Appendices I ,II ,II and IV below . Connect the dots .
There are many clusters of symptoms (Peripheral neuropathy , immune deficiency , etc ,etc) , but outside this remit

5.What to do :
This is where that qualified medical practitioner bit comes in .
Fix the deficiencies and reprogram the amygdala .
5.1Deficiencies :
5.1.1Vit D :the major culprit in western societies . Vit D3 supplements are cheap .
(especially for individuals with blotchy skin : check the alpha-lipoic acid level while you are at it)
5.1.2Sulfur : MSM supplements
5.1.3 Omega 3 supplements (flaxseed oil)
5.1.4 Add peppers (or some capsaicums) .( See Appendices below ) . This can be done in the diet , or directly via the mucosal membranes in the nose .
6.Reprogramming the Amygdala :
Not easy , but we have an entry through piperines (see Appendices II ,III) .
6.1Sneezing is known to use the same neural nexi as orgasm
See http://en.wikipedia.org/wiki/Sexually-induced_sneezing
(The ejaculatory mechanism come hell-or-high-water goes way back in evolutionary history)
It also concentrates the mind wonderfully , even more than hanging (apologies to Raleigh)
So , sneezing is a way of teaching the amygdala’s and associated neural networks to concentrate . Which is what we are looking for . It is independant of the reason for sneezing .
Interesting enough , it will also improve your sex-life . Train your orgasms !
Pepper snuffs. The amount is tiny (more is not better). Just sufficient to induce a sneeze .
(Tobacco snuffs used to be popular , but the tobacco companies killed them as insufficiently profitable . Probably will make a comeback , with anti-nasal irritants)
Other capsaicums in the diet will be synergistic .
In brief , when your attention is wandering , induce a sneeze with a tiny bit of pepper powder .
If there are no deficiencies or incipient diabetes , this should retrain the amygdalas .
A word of warning : do not take pepper or capsicums together with Loperamide(Imodium) . The Synergystic effects can lead to oiopd addiction (see Appendix III)
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Just to sum it up (low cost and simple ):
1.Take Vit D (1000 mg/day , more if blotchy skin)
2.Take MSM (3000 – 500 mg / day tapering )
3.Take Flaxseed oil (1 Tbs/day)l
4.Sneeze (pepper) (Very little )
But do consult a really qualified doctor . The above recipe cannot hurt , but if the damage is closer to the trunk , it might have only symptomatic effects .
You are welcome to add in all sorts of precursor chemicals , but if they are further away from the damaged branch , only temporary relief will occur .
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An interesting aside :
Hankies :
The ejecta of the sneeze has to go somewhere . Flu and cold organisms have hijacked the sneezing mechanism to replicate themselves (appropriate , given it’s ejaculatory evolutionary history) .
Still , the ejecta on your hanky is made up of active infectious agents (viruses or bacteria) , primed to look for a new host .
But what about the material already mangled by the host’s immune system ? Deactivated , with immune system markers and all . Your immune system really needs these as templates for the dendritic cells .
How to optimize this response :
Simply blow-dry the hanky , but do not wash it .
The rationale is simple : the infectious agents are destroyed or has to shut up shop (ie form spores , which resets their quorum mechanisms) . The already fractured cell-fragments of the infectious agent are not affected by low temperatures or small dehumidification .
Essentially , the balance between re-infection and immunization shifts in favour of the immune system .
Typical . Here I used tissues when I have flu , and threw away the recipe for shortening my misery .
Ignorance kills , but stupidity makes you feel bad .
Andre

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Apendix I
http://en.wikipedia.org/wiki/Methylphenidate
Methylphenidate (Ritalin, MPH, MPD) is apsychostimulant drug approved for treatment of ADHD or attention-deficit hyperactivity disorder,postural orthostatic tachycardia syndrome andnarcolepsy. It may also be prescribed for off-label use in treatment-resistant cases of lethargy,depression, and obesity. Methylphenidate belongs to the piperidine class of compounds and increases the levels of dopamine and norepinephrine in the brain through reuptake inhibition of the respectivemonoamine transporters. Thus, Methylphenidate possesses structural and pharmacological similarities to cocaine, though MPH is less potent and longer in duration.[1][2][3]

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Appendix II
http://www.diabetesdaily.com/wiki/Capsaicin
Capsaicin is being explored as a cure for diabetes by researchers in Toronto, Canada. Early work curing diabetic mice looks promising. Capsaicin was injected into pancreatic sensory nerves of mice with Type 1 diabetes because of a suspected link between the nerves and diabetes.
The American Association for Cancer Research reports studies suggesting capsaicin is able to killprostate cancer cells by causing them to undergo apoptosis. [4] The studies were performed on tumors formed by human prostate cancer cell cultures grown in mouse models, and showed tumors treated with capsaicin were about one-fifth the size of the untreated tumors.
Another study carried out at the University of Nottingham suggests capsaicin is able to trigger apoptosis in human lung cancer cells as well.[5]
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Appendix III
http://en.wikipedia.org/wiki/Loperamide
Loperamide ( /loʊˈpɛrəmaɪd/; R-18553[clarification needed]), a synthetic piperidinederivative,[2] is an opioid drug used against diarrhearesulting from gastroenteritis or inflammatory bowel disease. In most countries it is available generically and under brand names such as Lopex, Imodium,Dimor, Fortasec, and Pepto Diarrhea Control.

Many physicians and pharmacists believe that loperamide does not cross the blood–brain barrier. In fact, however, loperamide does cross this barrier, although it is immediately pumped back out into non–central nervous system (CNS) circulation by P-glycoprotein. While this mechanism effectively shields the CNS from exposure (and thus risk of CNS addiction) to loperamide, many drugs are known to inhibit P-glycoprotein and may thus render the CNS vulnerable to opiate agonism by loperamide.[6]
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Appendix IV
http://andreswhy.blogspot.com “ADD and TB” Oct 2010
Attention Deficit Disorder (ADD) and Tuberculosis(TB)
Andre Willers
26 Oct 2011

“Bright star , would I were as steadfast as thou art” John Keats (died of TB)

Synopsis :
This is not medical advice . Consult your doctor .
ADD and TB are linked by a deficit in Vitamin D , with very important threshold effects .
UV blockers , clothing and buildings have cleverly created whole populations of ADD and TB susceptible children . Not to mention other lurking nasties .

Discussion :
Melanin concentration :
The color of the skin .Usually erroneously associated with race . Evolved as a balance at any particular latititude between the VitD production from UV and Folic acid destruction .

This has been unbalanced mainly by Fashion .
Clothes and cosmetics .
Cosmetics are the oldest (cf Blombos caves in South Africa) .
Skin paint would reduce folic acid destruction , leading to higher viable fetus survival .
A literal matter of life-or-death to a small community .
Clothes ditto .

Ironically , clothes then evolved not to keep warm , but as shielding from too great Folic Acid destruction . This enabled the paleolithic Volkewanderung .

The women could match their fertility to the latitude . Remarkable .
The reason for Homo's great colonization success .

Flux :
The essence of the system was flux , as , indeed , it still is today .

Fashion goes too far , disturbing everything , necessitating everybody to run around like like mad to keep up , never mind get ahead .

Isn't Culture wonderful ?

Especially when this happens at genetic and epigenetic level .

What does this mean ?
This post was triggered by the finding that All Coloured TB sufferers in the Western Cape of SA had a deficiency of VitD . They had the correct skin color for the latitude , but too much clothing
This led to ADD. Which led to Gangs and Tik (Methamphetamine) , both concentration enhancers .
What a terrible trap .

Giving them Vit D supplements might help prevent future recruits , but the the present momentum remains .

The same is true for the ADD epidemic in the far northern or southern latitudes where they wear a lot of clothes and live in buildings .

Sports :
I really don't want to do this , but the evidence compels me .
Sporting activity in open sunshine with exposure to UVB is essential to physical and mental development of Homo Sapiens . There are also certain thresholds of UVB that must be exceeded .
If not , VitD below certain thresholds lead to Seasonal Affectional Disorder (SAD) which leads to ADD , which leads to cognitive concentrators like Methamphetamines(Tik , Ritalin) , too much alcohol, too much anything .

Riches , Fashion and Disease :
“Even the peasants wear clothes !”
Sigh . This simply means that their immune system's balance are disturbed . They are are more prone to diseases , unless supplements are given .
The balance is irrevocably disturbed . There can be no going back .But the bad effects can be ameliorated . There will be no New Balance .

But we all knew that when Fashion was invented .

Toujours , mes enfants .

And give a helping hand to the small ones .

Andre

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Appendix A
TB and Vitamin D .
Google “vitamin d tb” for latest findings .

The crucial point is that a certain threshold of Vitamin D concentration is necessary to trigger innate and learned immune system responses against TB and other nasties .
Thresholds , not just presence .This is why further studies are necessary to determine the critical levels .

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Appendix B
AttentionDeficitDisorder
Andre Willers
24 Nov 2007

Key Concepts:
AttentionDeficitDisorder
HyperActivity

Melatonin
Serotonin
VitD

MkIII and MkIV humans
CamelType

Discussion:
Four states are possible:

1.NoAttentionDeficitDisorder and NoHyperActivity
-> MkIII human -> desultory concentration -> lack of long-term application.

2.NoAttentionDeficitDisorder and HyperActivity
-> MkIV human -> obsessive concentration .

3.AttentionDeficitDisorder and NoHyperActivity
-> Learned helplessness -> neural weights are randomized ->apathy

4.AttentionDeficitDisorder and HyperActivity
-> HyperActiveFlea -> hop around ->fads utilized by state 1 and 2 humans .


Problem states:
State 3 is pathological , while State 4 is generally associated with children and juveniles of various ages .

State 4 to State 2.
Note that it is easier to shift State 4 to State 2 . This is one of the major driving forces in the epigenetic explosion of MkIV humans . HyperActivity can be left intact , while AttentionFocussing is conditioned .

The conditioning is social (schools , etc) and chemical (Ritalin , etc) .
A less problematic way would be to increase interest at a neurological level .

CamelType is one such way . (“The humps , the humps in the walls” a-la-HPLovecraft)
Originally evolved as adspeak , it is a way of increasing attention at a basic neurological way by alternating lower and upper cases in a pseudo-random way . This can be done dynamically on-screen , or better , on smart paper .

For example :

I TalK SenSe
i taLK sEnSe
i tAlk seNsE

There are 2^n ways of CamelTyping n letters in a sentence .
If in groups of three , a sense of order is engendered .

A neural-network mind looking at a screen where the upper and lower cases change pseudo-randomly is seduced into trying to deduce the rule .
Even if there is no rule , partial sequences of threes will be used and defended as rules
The neural-network cannot help it . It HAS to try and find correlations .
This is a well-known mechanism in horse-races , casinos and lotteries .
See also Sudoku , Chess , Go , Bridge , History , Science , etc .

State 3 to State 4.

State 3 is learned helplessness . This is Extremely difficult to work with , as there is no handle . The line of least energy is to convert State 3 into state 4 (AttentionDeficit stays the same , but induce hyperactivity) , then convert State 4 into State 1 or 2 .

State 4 seems to be a way-station for juveniles and other emotional cripples .

This is a favourite pathway for religious systems or armies .

Note that the most difficult pathway is from State 4 to State 1 . This can be observed in history .

This translates into “The weirdos seem to control all the committees.”

Where does , Melatonin , Serotonin , VitD fit in ?
VitD (or to be more exact , one and only one metabolic breakdown product (1,25D) is essential to trigger the expression of a large number of genes . Literally thousands of proteins cannot be formed without the intervention of this chemical . It is generally systemic . This means that you need it all the time . Gross shortages lead to things like rickets , but long before that metabolic abnormalities like auto-immune diseases strike , as juvenile immune responses are prolonged . The body cannot mature .

The genes expressing serotonin require VitD (hence Winter Sadness) .
Surface animals like humans have retained the capability of manufacturing VitD in their skins . Subsurface animals like fish (cod) have retained the necessary genes without solar input . Refer Esquimeaux.

The dosages : where the ping hits the plenum .
One healthy bikini clad girl needs about ½ hour of sunlight at median latitudes to get enough VitD (about 10 000 units) . A tbs of cod liver oil will give her about 1 000 units . Wearing clothes just leaving the face exposed is insufficient to generate enough VitD for procreation .

What a beautiful trap .
Humans in the high latitudes either have to migrate once in a lifetime to an latitude where there is enough sunshine (UVB) for enough VitD for essential gene-triggering to ensure fertility , or they had to eat fish products like codliver , caviar , salmon , etc to ensure the maturity of their own cell-cycles .

When neither is possible , human fertility rates fall . As what happened in the last century . What this stirs is ur-volkewanderung . All to be prevented by a VitD supplement .

The turnaround in Russian birthrates can be ascribed to the re-establishing of the Black-Sea holiday resorts .

And so it goes .

Andre

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Appendix C
AttentionDeficitDisorder 2
Andre Willers
8 Dec 2007

Key Concepts:
AttentionDeficitDisorder (see previous post)
HyperActivity

VitD
Biologically active sulfur for the skin
Essential Fatty Acids

Discussion:

I hereby give the overview and sources not mentioned in the previous post on AttentionDeficitDisorder .

Vitamin D
An excellent overview given in November 2007 issue of Scientific American “ Cell Defenses : Sunshine Vitamin”
www.beyonddiscovery.org/content/view.article.asp?a=414
“1,25 diHydroxyvitaminD3 is a direct inducer ofAntimicrobial Peptide Gene Expression” by Wang et al Journal of Immunology vol 173 p2909-2913,2004
“The Pleiotropic actions of vitaminD” Lin BioEssays Vol26 .p649 March 2004
“Vitamin deficiency” by Holick “New England Journal of Medicine , Vol357,no3,p266-281.july 19,2007.

Biologically active sulphur .
I have discussed this before . It is sufficient to note that animals whose skins we want to use for things like shoes and furs , need additional supplements of sulphur to be usable . (Google “MSM animal feeds”)
This means that humans are also deficient in biologically active sulphur .

Discussion:
Sulphur is essential in the normal deployment of skin organelles .There is a synergistic effect .

The less sulphur , the less Vit D.

Cheap clothing and urbanization means that most humans only expose a small part of their body for small periods to UVB . A general shortage of sulphur exacerbates the effect , as the skin cannot function optimally .

The net effect is a chronic shortage of Vitamin D .

In Utero effects:
Switching on and off of genes are especially important during gestation . If there is general shortage of 1,25D during this period , the available supplies are switched to the most important systems . (This is a very ancient system) . Certain later genes do not get switched on . This leads to immune problems . Notice the dominant effect of VitD vs Folic Acid .

Can this be rectified?
Yes . During growth spurts . The puberty+ stage is important .
As discussed before , AttentionDeficitDisorder and HyperActivity is not only normal in the spurt of growth in neuromass after puberty , but essential . Every human goes through this stage .

Intervention :
Northern latitude Europeans used to have a cheap source of VitD and Essential Fatty Acids in oily fish . They have destroyed these fish stocks and are now paying the price .

The problem is not only an on-going shortage of 1,25D , but an accumulated shortage of gene switches which did not happen .

Which is why there is an upper limit to VitD dosages . Too much , and the accumulated by-products of long-delayed gene-switch-on’s poisens the organism .

Why do these delays build up ? Because these steps are essential in maturing sperm and ova cells . The corrollary is , of course , that fertility rates in far northern latitudes are very low . This is borne out by evidence (Laps , Mongols , Esquimeaux,etc)

Actual Case study:
A male youth entering puberty with symptoms of chronic VitD deficiency .
Certain gene-sets do not switch on (extended neotony) . This is observed as babylike behaviour: hyperactivity and inability to concentrate for long periods .

Puberty makes this much worse .
Available resources of VitD , Essential fatty acids and Sulphur are stretched to breaking point by development imperatives .

Intervention is simply making these building blocks available.
The dosages :
Sulphur is critical . Cells divide ,especially brain and muscle-cells .
Give a lot of MSM : 10 gm /day
VitD uptake will be enhanced , if sunshine exposure of about ½ hr per day is followed . You will tan rapidly and skin will be smooth .
If this is not possible , supplementations should be done . But note upper limit .
Essential fatty acids : the building blocks of the brain . Two tablespoons of flaxseedoil and codliveroil a day

Adults:
If you plan lots of MSM and sunshine , be sure to include antioxidants .Make sure the exposure is logarithmic : a little at the start , then increasing rapidly . You will notice that you tan more rapidly (1/2 hr instead of days) . You are also more sane . (Less unstable)



Pak protector .
A theoretical construct by Larry Niven . Also known as grandmothers .The genetic effect is real .
Surviving Grandmothers are all Pak protectors to some degree .

Grandmothers like fish (all the ones I know) . Essential fatty acids etc .
Adding megadoses should be interesting .

Pak protectors on the female line are well known and real . But are there male Pak protectors ? We know that it would be an ancient system . The females groom the male into being the Pak protector . The effect is real . The male lives longer and is dominant . But the females are also caught in the same trap .The planet might have only one male Pak protector , and millions of female Pak protectors . Yet the females cannot co-ordinate without a nominal hierarchical head .

Any male can declare himself Pak protector . This has not been done for about 4 000 years . Interesting times indeed .

The Grandmother Party can indeed sweep the planet .
Who , after all , keeps the whole shebang together?

A toast to the Pak Party .

Andre

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