Toxin for Pain
Andre Willers
16 Aug 2013
Synopsis :
Capsaicum -> Resiniferatoxin(RTX) -> Botulinum toxin
in evolutionary sequence . Related . RTX is a too potent intermediary form .
All kill butons on dentrites , but the later targeting is more precise .
Discussion :
1.Take a capsicum molecule . (http://en.wikipedia.org/wiki/Capsaicin
) , tack on a complex on one side (http://en.wikipedia.org/wiki/Resiniferatoxin
) , then on the other side as well (http://en.wikipedia.org/wiki/Botulinum_toxin
)
2.Part of the Plant-Herbivore Wars .
Plants normally prefer to co-opt animals (rewards like
poppy(opium ,heroin) or coca(cocaine) are normally used . But there is also a
decrease in warning pain .
This is usually found in conjunction with some symbiont
(like a coral reef) .
3.RTX and pain .
See “Prickly Painkiller”
Scientific American July 2013 p 11 .
Quote:
“RTX homes in and kills only those neurons that produce a
protein called TRPV1 , which transmits the sensation of noxious heat and
inflammation . It does not harm normal tissue and other pain-sensing nerves.”
But a one-off kill of pain nerves is not optimal for the
plant . It will be more successful if the same animal returns again and again .
Gets addicted . Eventually fertilize the plant with it’s corpse .
4.Botox and RTX
Seen happening right now . RTX is final , like a vasectomy
or tubal ligature . The pain nerve is dead permanently .
Most humans will choose an open-ended option .
Botox kills butons in a certain class of nerves .
5.Botox with RTX
Botox with very, very small amounts of RTX should have some
very interesting effects . You can make the fix permanent , but this seems
generally a Bad Idea .
6.Curry .
A lot of capsaicum will interfere with these processes .
If a patient eats hot curries , botox therapy will wear off quicker
.
7.BreakUp products .
Simple molecules like capsaicum , instead of breaking down
and becoming less complex , become more complex .
Not everything in the cauldron of a cell is programmed
(deliberately so) . Some novel molecules form . If they are advantageous , they
are selected .
But the process is very fast (not related to DNA) .
Epigenetic if successful .
This sequence (Capsaicum,RTX,Botox) is recreated in the gut
cells seconds after eating a curry . After 3 generations there is an epigenetic
coding .
8.Chaperones :
This sequence has been around a long time . Chaperone
molecules have evolved to speed up BreakUp products .
And RTX is the next step after capsaicum .
9.What does this mean ?
Societies that eat a lot of capsaicums like curries ,
chillies ,etc . lose empathy . As BreakUp RTX kills pain nerves permanently ,
greater and greater stimuli are needed .
Think Aztec or serial
killers after asprin .
10.True love .
Requires empathy . Fellow feeling of pain . For that you
would have had to feel pain .
Love goes better with no curry .
11.Interesting aside :
Monogamous plants ?
A bit farfetched even for me . But there is a niche . In
desert conditions or extremely fertile conditions . RTX coding is used to
initiate speciation .
Delineate boundaries .
Insist that the garlic cloves must be from the same pod .
Your gustatory success depends on it .
12.Botulinus or RTX poisoning :
Flooding the system with capsaicum should help
Smoothing Botox delineation : capsaicum . A nice hot curry .
With RTX poisoning , a bit more robust reaction is called
for .
Ground 3 garlic cloves out of the same pod in a bit of water
. Suck it up into a syringe and inject it intravenously . Better than nothing .
A sort of anti-pain . This will give a high because of
endorphin releases (the hurt stops) .
But it is addictive (the hurt will resume) .
Extra–currycularly yours
Andre
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
Appendix A
See
xxxxxxxxxxxxxxxxxxxxxxxxxxx
No comments:
Post a Comment