Tuesday, October 22, 2013

Calico Immortality


Andre Willers
22 Oct 2013
Synopsis :
Calico : A major new human initiative in Anti-ageing enterprise has been launched by Google .
Discussion :
1.Why the name Calico ?
See Appendix A . Calico cats are intimately related to genetics .
2.Who and How much ?
See Appendix B .
Big names and a lot of money . Where is L . Craig Venter ?

3.What is already happening ?
A lot of data-mining on blogs , emails , etc .
The same is occurring on any site associated with longevity , genetics , etc .
One of the reasons why Google arrogated rights to certain content on it’s platforms .
4.What is next ?
There are now three very big , very powerful Bio-Genetic Champions in existence :
4.1 L.Craig Venter and the petrochemical industry .
4.2 Bill Gates Foundation and Public Health
4.3 Google and Anti-ageing .
5.Struldbugs :
Competition between these entities will hopefully avoid the Struldbug Scenario .
See Appendix C
6.Singularity :
Even the process of creating Calico makes the Singularity more likely by at least two orders of magnitude .
6.1 Co-opting all knowledge without a Hysterical Focus .
6.2 Forcing the examination of the effects of longevity without crashing all systems in the run-up .
The Interesting Times are only just starting !
Appendix A
Because genetic determination of some coat colors in cats is linked to the X chromosome, calicoes are nearly always female.[2][4] Because of the genetics involved, calico males generally have impaired vitality and are almost always sterile.

Appendix B
More details on Google’s mysterious Calico project have emerged, revealing the search giant intends on investing, at the very least, “hundreds of millions” in the initiative. Announced last month, Calico is a project borne from Google’s special Google X labs, with an endgame to take on major illnesses and aging. The initiative is being led by ex-Genentech CEO Art Levinson, who also serves as Apple chairman.
After some digging around Silicon Valley, Fortune writer Dan Primack found that Calico is focused on finding the root cause of various diseases and conditions, something many companies today fail to focus on. Most importantly, however, the project wants to address genetic causes of aging, and whether or not drugs can slow or even stop them. At the very least, Google wants to see how the quality of life can be improved for someone that’s in their 70s, 80s, etc.
For example, what if you examined the genomes of thousands of healthy 90 year-olds from all parts of the world? What genetic similarities do they have? Or, perhaps, what happens to most of us that didn’t happen to them. Even if this didn’t result in longer life, it perhaps could at least lead to an improved quality of life for folks on the back nine.
The project will act more as a research initiative rather than, as Primack puts it, “a biopharma startup that will be in clinical trials within a couple of years.” Many smart pieces are being moved around, and there’s very clearly a substantial amount of money being put into the project. When Google puts resources into X lab projects, the company tends to produce fascinating results—self-driving cars, balloon Internet, Google Glass. With such a unique portfolio, and given what we know about Calico, the search giant’s new project could prove to be Google’s most important undertaking yet.
Appendix C
The Struldbug Scenario
In Jonathan Swift's novel Gulliver's Travels, the name struldbrug is given to those humans in the nation of Luggnagg who are born seemingly normal, but are in fact immortal. However, although struldbrugs do not die, they do nonetheless continue aging. Swift's work depicts the evil of immortality without eternal youth.
They are easily recognized by a red dot above their left eyebrow. They are normal human beings until they reach the age of thirty, at which time they become dejected. Upon reaching the age of eighty they become legally dead, and suffer from many ailments including the loss of eyesight and the loss of hair.
Struldbrugs were forbidden to own property:
As soon as they have completed the term of eighty years, they are looked on as dead in law; their heirs immediately succeed to their estates; only a small pittance is reserved for their support; and the poor ones are maintained at the public charge. After that period, they are held incapable of any employment of trust or profit; they cannot purchase lands, or take leases; neither are they allowed to be witnesses in any cause, either civil or criminal, not even for the decision of meers (metes) and bounds.
Otherwise, as avarice is the necessary consequence of old age, those immortals would in time become proprietors of the whole nation, and engross the civil power, which, for want of abilities to manage, must end in the ruin of the public.


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