Thursday, March 17, 2011

Genome Clouds .

Genome Clouds
Andre Willers
17 Mar 2011

"Trailing clouds of glory do we come" Wordsworth .

Synopsis:
An organism can be defined by clouds of the real and virtual genomes of the organism and of all it's sub-organisms . Computation of genomic structures are greatly enhanced by using proven quantum-like techniques .

Discussion :
As DNA sequencing grows faster , cheaper and smaller , we will within 20 years approach Drexler's idea of a sequencer , compiler and computer much smaller than a cell inside each and every cell .

Even now , we are drowning in data . Billions of DNA pairs , millions of organisms , not to mention protein foldings and the Histone code .

What is a poor limited mind to do ?
Why , the normal refuge of the uncertain : Statistics , Quantum Mechanics and Robots.

Take the Human Organism as reference .
This consists of the Human Genome (more or less known) , Histone Code (very little known) ,
In it's fractal nature , there are sub-systems :
These consist of the Mitochondria , gut bacteria, immune system , diseases , viruses , etc , each with their associated Histone Code and metacontrols where applicable .
See http://andreswhy.blogspot.com "Phene System II" Feb 2011

Many of these sub-systems have bigger genomes than humans .
Many switch roles depending on various triggers .

Add Virtual Genomes
Virtual copies in computers or cellular high-risk cancer labs

Add influx of strangers via ingestion of food , air ,water , wounds etc .

These are all much easier to understand if seen as Clouds , instead of particles .
The same as Boyle's Gas Law is simple compared to doing it molecule by molecule .

Virtual Genomes
These will make things much easier , as pre-prepared positions are possible .
Evolution is highly conserved . The same bits and pieces keep on cropping up .
Real-time monitoring and steering become possible .
Why Mother Nature has those pesky , high-risk cancer labs where evolution is on fast-forward . She's one step ahead .
See http://andreswhy.blogspot.com "Prodigies , Primitives and Cancers" 9 May 2007


Cloud Rules :
Reducing gigabytes of data to fairly simple Cloud Rules would be daunting task if not for two things :

1,Theoretically , it can be done .
See http://andreswhy.blogspot.com "P vs NP " Feb 2011

2, Robotic systems .
2.1 See http://andreswhy.blogspot.com "AI Update Jun 2009'
2.2 There is an article on Robot scientists in Jan 2011 ScientificAmerican , giving the state of published art .
Aberystwyth University in Wales is the leading center .

Pharmaceuticals
This process is ideal for large or small pharmaceutical companies , and , indeed , is already being used in this way .
Algorithm :
1, Shotgun sequence some new organisms
2, Add into cloud of known genomes .
3, Chase through Robot scientist.
4, Test

FDA approval now takes up such a long time that the maximal profit period of a new drug is eaten away . Leaks and clones happen . More money can be made by simply being there "Firstest with the mostest"

Gaia
The process is fractally upward as well .
With humans in the loop , Gaia will become aware , then self aware and then …
See previous posts on AI's .
A Planetary Cloud of genomes and virtual genomes .

Big Sister is not only watching you , but every cell in you and every bug in you .

Voyeurista's Ho !

Andre

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