Sunday, March 31, 2013

Mosquitoes falling asleep on the job .

Mosquitoes falling asleep on the job .

Andre Willers
31 Mar 2013
Synopsis :
Mosquitoes select humans with low melatonin levels to prevent themselves falling asleep .
Discussion :
1.Mass of mosquito ~ 2.5 mg .
2.Mass of blood meal ~2.5 mg . Mosquito’s mass doubles .
3.If the human is asleep (ie high melatonin concentration) , this means a huge influx of melatonin .
4.The mosquito’s diurnal rhythms are disturbed . It risks falling asleep . See Appendix III
5.It risks increased predation while it feels sleepy : see Appendix I
6.Melatonin decreases plasmodium fellow-travellers . See Appendix II
The mosquito benefits from malaria since it leads to a herd of “milk-cow” humans too lethargic for active counter measures,
but who are reservoirs of the disease . A nasty bunch of cronies .
7.Mosquitoes have thus evolved the following characteristics:
7.1 Activity in early evening or early dawn , when humans are awake and melatonin concentration is low .
7.2 The mozzie whine . This keeps humans awake (one mosquito can keep a whole roomful of humans awake) , thereby lowering melatonin .
Sure , the whine is used as a sexual selection criterion . Exactly for this reason . The female that can keep humans awake is a fitter partner and is accordingly selected by the males .
8.How does the mosquito know what the melatonin levels are ?
Those long chemo-sensitive antennae .
9.We can convince the mosquito that a closed volume does not contain suitable prey by spraying with
Super-melatonin like Valdoxane and their ilk will require a lot of testing .
10.No resistance can develop without changing the whole cyclic nature of the mosquito .
This will disrupt the plasmodium life-cycle .
11.Driving mosquitoes mad :
Limburger cheese (see Appendix IV) and Melatonin spray (see Appendix I , II , III) together should disrupt the mosquito’s
nervous system (drive it mad) . This will disrupt the whine patterns , signifying that it is not a fit mating partner .
The mosquito might realize the threat and depart (most likely) or kamikaze (fall asleep) .
Sleep kamikaze . A new one .

Caffeine is a powerful insecticide , especially for mosquito larvae .  Also very old . So it will be in the mosquito’s antennae list of bad things to avoid .
13. Though you should draw the line at teabags or coffee grounds between the toes .
14. A cheap and simple deterrent :
14.1 Chase the mosquitoes away .
Get a ordinary spritzer (hand atomizer) . Fill it with very strong cold coffee into which some melatonin has been dissolved . Spritz it in an enclosed space . The effects on the human should be interesting . If necessary leave out the coffee .
14.2 Drive the mozzies mad .
Limburger cheese (see Appendix IV) . A nice limburger cheese sandwich with coffee and melatonin spritzers will keep all sorts of bloodsuckers away .

As divorce duellists say :
“Limburger sandwiches for two and coffee for one”

Drive the mozzies mad , not vice versa .
Appendix  I
Predation risk due to increased mass of blood meal .
“jet-lagged travellers may be more susceptible to getting infected with malaria. 
Appendix II
Terminator melatonin .
·         Plasmodium
Plasmodium is a genus of Apicomplexan parasites. ... simultaneously during the night It is known that melatonin plays a role but how this ...
102 KB (14,130 words) - 18:40, 30 March 2013
·         Plasmodium falciparum biology
Plasmodium falciparum has been the focus of much research due to it being the ...least in part dependent on melatonin secretion by the host. ...
315 KB (44,863 words) - 06:54, 27 March 2013
·         Drug discovery
part of combination therapy for multiresistant Plasmodium falciparum . ... Discovery and development of melatonin receptor agonists ...
25 KB (3,502 words) - 15:16, 9 March 2013

Appendix III
Do Mosquitoes Sleep?
 By Elizabeth Miller    
Yes they do. Unfortunately, they don't like to sleep at the same time we do. Most mosquitoes are active at night or at dusk and dawn, and rest or sleep during the day.
Appendix IV
Hyper-attractant for mosquitoes
Limburger cheese .
The cheese is especially known for its pungent odor commonly compared to body odor.
Brevibacterium linens is the organism responsible .
Evolve a hyper-scent image (scent idoru) .

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