Wednesday, May 08, 2013

Cure for Gray Hair .

Cure for Gray Hair.

Andre Willers
8 May 2013
Re pigmentation has been done using a modified pseudocatalyse . Both for age-related graying and vitiligo .
Discussion :
1.This has been known for some time .(1992) This is the first time a large-scale study peer-reviewed in a mainstream journal has found for the effect .
See Appendix A and Appendix B
2.This means that big pharma’s and cosmetic companies will be forced into a race .
3.The prize is a market of about 2 000 million people , with a constant incoming stream of agers .

4.  Vested Interest Effect :
Big vested interests in cosmetics , hair dyes , etc actively discouraged development . (Nothing to patent ?)
Only the present media-storm (a mini-hysterical focus) may be able prompt some development .
5.There has been something similar : Viagra .
A proven remedy displaced all the nostrums .
The same thing will happen with gray hair . But this time the nostrum market is much larger . Think soaps , hair dyes , shampoos , conditioners , shower gels , etc , etc .
6.Unintended effects :
Old-age markers . See Appendix C
6.1 Gray hair as a dominance marker will disappear , unless it is dyed back in .
Sigh! The Chairman dyes his hair white . Typically human .
 6.2 Sexual cues will become even more unclear than at present . “And Cougars will stalk the land”
6.3 Alopecia might very well reduce . Reduction of hydrogen peroxide at the root follicle should reduce hair-loss .
6.4 Skin-heads will become unfashionable .
6.5 Tattooing (artificial hair-patterns) will probably become unfashionable , too . But expect dermal led-implants . A hide of many colours .
6.6 Nostril hairs :
The Rapunzel Syndrome (See Appendix C) . This will lead to stronger sense of self  , with a concomitant reduction in demand for psychotropic drugs .
6.7 Moustaches will make a big come-back .
6.8 Increase in demand for pheromone scents or just deoderants . Old men will become more smelly .
6.9 Combs (see Appendix D)
Combine this with cheap 3D printing now easily available and designer combs and brushes  (even dispensing the PC-KUS) can be personalized as fashion accessories .
This influences sexual selection . A mate that can design and print comb accessories is fitter  and will attract better suitors .
I can see the excesses of this trend in my mind’s eye . (Think hairstyles of the French aristocracy , only now aided by computers , apps ,etc)
6.10 Hair Stylist Advisors will then become a highly fashionable , highly skilled occupation , putting hairs through hoops dreamt up in computers .
A poor hair will feel like crawling back into the follicle .
Hair Psychologists already exist (new to me too) . Google it . But these ones will treat the hair itself , not the owner . . Suicidal hairs . The mind boggles .
6.11 Hats will make a comeback .
. See Combs in Para 6.9  and  6.10 above . Use 3D printers to create personalized hats as fashion statements .
A hat is also a useful platform for all sorts of gadgets : cameras , cellphones , Google Glasses , health monitors , Bluetooth , etc.
The Hatter Advisor , like the Hair Stylist Advisor , will then become a highly fashionable , highly skilled occupation .

6.12 Shoes .
A really unintended consequence . Once 3D printing becomes fashionable , it is but a short step to designer shoes .
Cordwainer Advisors : . A cordwainer (or cordovan) is a shoemaker/cobbler who makes fine soft leather shoes and other luxury footwear article
Shoes printed 3D from scans of your feet , to your own design . No more pinching . Anatomically correct .
6.13 Handbags :
The same as for shoes .
Incredibly , there is no English word for the maker of handbags !
Call them a Modiste :    One that produces, designs, or deals in women's fashions.
Call them a Modista :    One that produces, designs, or deals in men's fashions.

A modiste will then advise on the whole ensemble : handbag , shoes , hairstyle , accessories , clothes , nails , etc .
A really highly skilled artist , which must also be completely au-fait with 3D printers , fashions and on-line patterns .
Will cost you a pretty penny . But Artificial Intelligence Franchises will help .
6.14 Nails :
See Appendix E
Profession : Nail Stylist (Manicurist)
Another unintended consequence : nails are keratin . Their tactile sensitivity can be maintained or even enhanced by using the same technique .
Areas affected would be sport , especially golf and tennis . All music . Medical work . Any endeavour involving tactile sensitivity .
6.15 Artificial Intelligence Franchises :
The demand for on-line skills for Modiste , Nail Stylist , Cordwainer , Hair Stylist Advisor will outstrip supply .
A fashionista can print a new outfit for a few dollars . But they need a personal design . An advisor will help . But personal , human advice will be expensive .
An advisor can franchise expertise via an AI .
6.16 “ Hair-the musical” will make a big comeback .
6.17 Umbrella’s
You guessed it . All these fancy accessories and hair will not be rain-proof . So add an Umbrella advisor . There is not even an English word for umbrella maker .
Use Umbrellista for Umbrella Advisor . The usual 3D printing .
6.18 Wigs . Perruquier Advisors .
A perruquier is a wig maker.
One would think that wigs would completely disappear . But the combination of metamaterial technology and fashion will very probably lead to hi-tech wigs that blend in with the normal hair . They will have metamaterial EKG pickups on or in the scalp (like SQUIBS) , with processors and antennae in the hairs .
6.19 Green Polar bears .
See Appendix F
Algae in the hollow tubes of polar bears’ hairs turn them green . This leads to a loss of insulation . The bear will search for warmer climes .
An aerosol spray of PC-KUS and algae should motivate them to move to prepared habitats . Same for wolves .
“She asks me why
I'm just a hairy guy
I’m just another modista , being chased by a green polar bear .
Well , that was fun !

Appendix A
Gray Hair And Vitiligo Reversed At The Root
Monday, May 06, 2013
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Source : Federation of American Societies for Experimental Biology
New research in The FASEB Journal suggests that loss of skin or hair color can be corrected by a new compound -- a pseudocatalase -- that reverses oxidative stress
Bethesda, MD—Hair dye manufacturers are on notice: The cure for gray hair is coming. That's right, the need to cover up one of the classic signs of aging with chemical pigments will be a thing of the past thanks to a team of European researchers. In a new research report published online in The FASEB Journal ( people who are going gray develop massive oxidative stress via accumulation of hydrogen peroxide in the hair follicle, which causes our hair to bleach itself from the inside out, and most importantly, the report shows that this massive accumulation of hydrogen peroxide can be remedied with a proprietary treatment developed by the researchers described as a topical, UVB-activated compound called PC-KUS (a modified pseudocatalase). What's more, the study also shows that the same treatment works for the skin condition, vitiligo.
"To date, it is beyond any doubt that the sudden loss of the inherited skin and localized hair color can affect those individuals in many fundamental ways," said Karin U. Schallreuter, M.D., study author from the Institute for Pigmentary Disorders in association with E.M. Arndt University of Greifswald, Germany and the Centre for Skin Sciences, School of Life Sciences at the University of Bradford, United Kingdom. "The improvement of quality of life after total and even partial successful repigmentation has been documented."
To achieve this breakthrough, Schallreuter and colleagues analyzed an international group of 2,411 patients with vitiligo. Of that group, 57 or 2.4 percent were diagnosed with strictly segmental vitiligo (SSV), and 76 or 3.2 percent were diagnosed with mixed vitiligo, which is SSV plus non-segmental vitiligo (NSV). They found that for the first time, patients who have SSV within a certain nerval distribution involving skin and eyelashes show the same oxidative stress as observed in the much more frequent general NSV, which is associated with decreased antioxidant capacities including catalase, thioredoxin reductase, and the repair mechanisms methionine sulfoxide reductases. These findings are based on basic science and clinical observations, which led to successful patient outcomes regarding repigmentation of skin and eyelashes.
"For generations, numerous remedies have been concocted to hide gray hair," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal, "but now, for the first time, an actual treatment that gets to the root of the problem has been developed. While this is exciting news, what's even more exciting is that this also works for vitiligo. This condition, while technically cosmetic, can have serious socio-emotional effects of people. Developing an effective treatment for this condition has the potential to radically improve many people's lives."
Special note: This report follows up on a 2009 study, which describes the cause of gray hair. See for the press release for that study, and to access the full report.
Receive monthly highlights from The FASEB Journal by e-mail. Sign up at FASEB Journal is published by the Federation of the American Societies for Experimental Biology (FASEB). It is among the most cited biology journals worldwide according to the Institute for Scientific Information and has been recognized by the Special Libraries Association as one of the top 100 most influential biomedical journals of the past century.
FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to its member societies and through collaborative advocacy.
Details: Karin U. Schallreuter, Mohammed A. E. L. Salem, Sarah Holtz, and A. Panske. Basic evidence for epidermal H2O2/ONOO−-mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB-UVB-activated pseudocatalase PC-KUS. FASEB Jdoi:10.1096/fj.12-226779 ;


Appendix B
n Reply To: Benjammin's post @ May 4 2013, 10:19 PM

I would suggest you get a little more educated on this vitiligo news. The news source I mentioned was but one of dozens that picked up the story. 

Have you heard of these folks from Bradford University or even the medical journal itself? It's been around since 1912. This is about as prestigious as you get:

1) the Bradbury people behind this are experts on pigmentation - world class researchers

2) You don't get published in one of most well-respected medical journals for being something that 
the medical community scoffs at. This discovery even illicted high praise
from the journal's well-respected editor. 

3) I counted over 40 media outlets that covered the story - and that is just from a 3-day span. Surely more to come.

Vitiligo forums were buzzing about this over the weekend.

Upon request from the journal, I have seen the before and after photo results from the offical study and they are very impressive. No less impressive than Clinuvel's.

Pretending it doesn't exist and scoffing at it doesn't change the facts. You'll be hearing a lot more about this research and very soon. 
Appendix C

Old Age Markers

Andre Willers
23 Dec 2007

Why do men growing older get grey hair and bald pates?
Why does their ear-hairs , nostril-hairs , eyebrows and pubic hairs grow much longer than younger men’s ?

Why are old men smelly ?

Involuntary Altruism .
We know that evolutionary mechanisms operate even after the last child , because we have evidence of the GrandMother effect . Older  Females in a family (ie with the same genes as their offspring) have evolved menopause and an extended lifespan . More and healthier grandchildren survive with a grandmother . The mechanism is part of general evolutionary theory .

So what about old men ?
They are sacrificial old goats !

A family fleeing predators would have a markedly better chance of its genes surviving if the older males are marked for predators . The predators gain by not having to expend too much energy . But the evolutionary kicker is that  predators on hominids are usually of the big cat family . Their cubs have to be taught to hunt on easy prey . Older , slower , weaker hominid males are recognized by their markers .
So , they learn from early on what the markers are . A tacit bargain was struck .

The Leopard-class of big cats specialized in hominids . A saber-toothed variety evolved pari-passu with homonins . A desperate arms-race of survival ensued . I refer you to the tooth-holes in the skulls of some unlucky homonins found fossilized in Africa . The end-cat was a large black leopard with widely spaced saber-teeth and a high intelligence . Black because it was a night-hunter (when homonins nested) , widely-spaced saber-teeth to fit the growing skulls of homonins , high intelligence to keep up with the growing intelligence of their prey . But they did not have hands . They were exterminated , probably by concerted human effort . The last fossil record found was about 200 000 BCE , roughly contemporaneous with MkI Humans . The development of weaving probably had more to with their demise than anything else .

The present survivor of this class (the spotted leopard) preferred baboons and monkeys , and thus survived .

This went on long enough (estimated 7 million years) for a true instinctive fear to have been programmed into the amygdala(like for spiders and snakes) .

Go to the Zoo and look at a black leopard .
If he looks at you , you feel a frisson of fear . This is your amygdala kicking in . (You don’t feel the same looking at a lion .)
Of course , the black leopard is a pussy-cat compared to the previous terrors .

But , we can create an ideal hyper-image (idoru) .
A Black cat-head , broad with very widely spaced reflecting golden eyes , widely spaced saber-teeth . I suspect that saber-teeth wider than the eyes will immediately kick in the amygdala responses . The same effect is noticeable in horror-movies . The ratio of width-of –mouth to width-of-eyes seems to play a critical role .
So , if you have eyes close together and a wide mouth , do not show your teeth . The response is not rational , but instinctive .

Psychopaths are reputed to feel no fear . Is this true a for genetically programmed response like this ? There might be some therapeutic benefit in making psychopaths or extreme sociopaths feel terror . The mirror-neuron structures of empathy  that should have formed in childhood can then be reconstructed .

To resume the argument :
Ropes and nets woven from plants by hands negated physical strength . Hence , MkI human males and females were roughly the same size and strength . Unfortunately , these fibres left no physical record until the impressions left in ceramics circa            30 000BCE . But we know that clothing became widespread as a result of the Toba-winter (72 000 BCE) . There was no time to invent new technologies , so old  weaving technology was adapted to provide insulation in the survivors .

The old-age markers .
The smelly bit first (ie the evolutionary oldest)
The hairs around the glands extruding smelly compound grow longer with age .

Normally , body hair grows a certain length , then stops , dies and is replaced . Normal body hair around glands are crinkled , twisted and convoluted to give maximum surface-area to the scent-molecules . Pubic hair is the best example .

Ears : Tufts growing out of the ears broadcast the earwax scents. Also , hearing gets harder .

Nose : Nose hairs are unique to humans and supposedly evolved due to the smoke-filled environments after the usage of fire . The effect is to capture molecules on exhalation , store them , then release them on inhalation . In other words , a short term memory . The vomenerosal organs in the upper palate and connected to the nose are also connect to very ancient parts of the brain concerned with identity . Pheromones and other chemicals (like antibodies) extruded by the body are stored by the nostril hairs and fed back to the vomenerosal sensors . The body is continually reminding itself of its identity . This also happens to be the definition of self-awareness .
The intriguing speculation is that this method of base-line identity setting extends to the immune system . Evidence from yoga not only indicates self-awareness shifting due to concentrations of “I am I” pheromones by breathing through the nostrils , but that the immune self-definition is affected as well .

The Rapunzel Syndrome  .
Too small a concentration of nasal hairs causes insufficient self-definition . Auto-immune diseases like arthritis , asthma , diabetes etc follow , as well as meme-diseases like low self-esteem , drug-abuse . Note the effect of cocaine sniffing on personality coherence .

Too large a concentration of nasal hairs like in old men , makes the person very self-assured with “presence” , the presence being molecules broadcast . “Charge! and damn the torpedoes .”

Notice that breathing masks like worn in very cold or very hot climates have similar concentrating effect , but weaker by an order of about 10 . (Norse , burkas,etc)

Intervention !
Cheap and easy . Noseplugs mimicking dense nosehairs will do the trick .
I am actually embarrassed that nothing more complicated is needed .
Noseplugs made of coarse organic wool should do the trick .
Even cottonwool will work , though it is a bit too dense .

The poor man’s noseplug . Notice that individuals with moustaches always were always self-assured ,even if they were completely wrong . Societies with moustaches were losers . Celtic tribes had moustaches .  So did Hitler and Stalin . Breathing in their own definitions of I all the time explains a lot .

Note the law-enforcement fashion for moustaches .
It is not a fashion , but a statement .

The Eyebrows.
Eyebrows have a long and honorable history of enabling mammal survival , going back to the dinosaur days . The eyebrow is dense with sebaceaous glands , pumped out onto the eyebrows and spread onto the environment . For a burrowing rodent , it was essential to know where it had been (identity and location) , as well as who had been there before and how long ago . Refer to muskrats ,beavers , etc . Humans do the same . This is why dogs jump up and try to lick your face . They are not trying to lick your face . They are trying to lick your eyebrows . Your scent-identity is being broadcast all the time by the glands in your eyebrows . Hence old men with bushy eyebrows .
But , while this would have been fatal when lots of predators were around , in “civilized” surroundings this gives the person a certain edge as being wise .
The normal heat-envelope around the body ensures that most of these pheromones go upwards , but standing on your head a lot will change that . Sigh . Another yoga shibboleth bites the pheromone . A full head covering like middle-age armour would have exaggerated effects on self-esteem .
Ice-hockey masks ? I rest my case.

A Christmas Present :
Millions of dollars can be made by an Eyebrow Scent . You owe me 5% for the idea , whoever you are . I hereby claim intellectual property right on the idea at Cape Town on 24 December 2007 AD .
The act of kissing only exists to bring the nose and eyebrows into proximity . Lots of compatibility signals ensues .

Applied scents are lies . Will an Eyebrow Scent significantly change human society ?
No . But you can make a shitload of money out of it , since nobody has thought of it before .

Armpit hairs .
Not much to be said here . Too fat , and they are worn away . Otherwise long and straggly .

Pubic hairs .
Pubic hairs in men grow long and straggly in old age . These capture more urine scented molecules and sets him up for a predator .

Grey Top Hair
As you can see , changing the colour of
hair to grey is a long range signal to a predator . This was sufficient at first .

Bald Pate .
Since females can also go grey , albeit later than males , the bald pate evolved to signal predators . Imagine a family running through the long grass with the cats in pursuit . They see a flashing bald pate bobbing up and down in the grass . They know that this is an old hominin male .  Note that females do not go bald .

Self-referencing scents .
As you can gather from the above , the very definition a person makes of itself down to immune-level can be determined by scent-feedbacks .


As I promised , smelly old men .
Barber pubic hair and underarm hair to about 2 cm .
Bad feedback mechanisms are halted . Simple noseplugs restores some degree of selfpride .
Always shave .

The same holds for normal ages (20-40) . Variants of ice-hockey masks where the top holes are blocked might be considered .

And so it goes .

Appendix D


Andre Willers
24 April 2008

The oldest profession .
Hair Dressing and Grooming .

The time-traveller with hairdressing and grooming skills can get a job anytime back to hominid days . Beats plumbing any day .

This partially explains the queer gene : Faux-queer . A cunning stratagem to get close to females without the usual male chest-beating .


Grooming is built-in to the hair of mammals .

Hairs get tangled and knotted ( see Theory of Knots) . Your personal experience is that after day’s activity and a night’s sleep , your hair gets tangled and knotted . The theory shows that it is nearly certain that this will occur in any system with three degrees of freedom .

Tangled hair is a bit of no-no to our homonin . It shows that it cannot get a grooming partner . Parasites also have access to unprotected skin .

Chaos first did the weaving with knots and tangles .

Un-weaving was then invented .

Initially fingernails , then a sharp , hard pointed stick ( a one-toothed comb)  to tease the knots apart ..
When a favourite stick was kept , it became a tool .

A one-toothed comb .

Found all over in old sites , but usually called something else .

Plaiting of hair followed . Then some unsung woman genius inverted it and plaited grasses and other fibrous growths . Ropes and nets were invented .
Physical strength became unnecessary .
Mk I  humans followed .

MkII humans followed after Toba , when weaving was invented as insulation (clothes) . So was fashion , and the world was never the same .

From the evidence , fashion seems to be a more powerful driver than anything . I would like to put an “except” here , but from the Greenland evidence where people starved to death because eating abundant fish around them was “out of fashion” with some old bishop I cannot .

What is of interest is that un-weaving was invented first , then weaving .
Note the correlation of Peace being invented before War .

Multiple-tooth combs .
An invention so ubiquitous that every human on the planet today has one and uses it at least once a day .

It enables an individual to self-groom . You can comb out the tangles in your hair or pelt by your own , without help .

This had an enormous effect on the development of civilization . The very concept of individualism is predicated on the existence of combs .

It frees the individual from the tyranny of the group .

An unkempt individual is excluded . No ifs or buts . Look around you at the homeless people . Once grooming is lost , so is social acceptance and survival . Hence the large number of spaza-hairdressers . It is not an affectation , but sheer survival .

See  “Super Refugee”

Note the insistence of disciplined groups like the military or police to hair grooming . Or the inverse , the trust civilians have for anybody with a taut haircut .

See  “Old Age Markers”
Note the hairstyles of the Mandarin class in China : shaven in front , denoting wisdom from survival , and extravagant hair (plaits) at the back , denoting humanity .
Hence , a monk will shave his head denoting a divorce from human concerns .

If someone obviously not in a religious order shaves his head (like bouncers , etc) they signal an indifference to the grooming order . They are essentially doomed . An extremely interesting feedback cycle is initiated that ends in the marginalization of such individual . They  tend not to have children .

It must be noted that these are universal hominin markers , operating at well below conscious perception .


Appedix E
Human Nails .

Andre Willers
23 August 2007

Synopsis :
Human fingernails are intimately linked to rhythm and pattern recognition neural systems . It is also the third most important element in human sexual selection .


Evolutionary roots:
Hominid bipedalism evolved quite early  .
Moropithecus (16 to 25 MY ago) showed adaptations to upright posture .

They walked on branches and clutched other breast-high branches for stability .

Science DOI : 10.112 / science.1140779
New Scientist of 9 June 2007 p18 “Four legs new ,two legs much older”  “The Squat and the Wobble” )

This adaptation was lost in some streams of  homonids , but retained in the homonin (ie our) ancestors . This means that for significant evolutionary time our ancestors clung to thin branches with their fingers curled around the branch and their fingertips pressed against the wood ..

The branch is not only a mechanical support , but also transmits information . The branches are elastically resilient , so waves caused by any large organism walking and stalking about can be picked up by suitably sensitive sensors and the type of organism identified by a neural-network .

The canopy-network is an information-rich network because of it’s resilience . Similar type of signals can be carried by the ground  (cf elephant feet ) , but the damping and bandwidth is totally different .

Small wonder that homonins have recreated the canopy in the Internet .

An Internet created by elephants or whales would look completely different .

The finger :
The sensor-network is the pressure-receptors below the nail . The finger part in touch with branch is liable to tissue destruction , abrasion and calluses . Any sensors here are degraded by wear-and-tear .

But , hydraulic pressure transmits around the finger bone to compress the pressure receptors in the nail-bed against the unyielding nail , giving quite fine detail to a neural-network .

Some Corollaries:

1. IFF (Identification Friend or Foe)

This evolved literally at the start of the dinosaur/mammal split , derived from reptiles and has been refined ever since .

Any predator has a particular rhythm caused by putting it’s feet down in particular sequence (gait) .

If the predator is on a branch (or any resilient surface) , the rhythm is transmitted  .
Soil can also be a medium , but less efficient (cf elephants)

This neural-network for IFF  evolved under the fingernails .

In other words , a lot of rhythm recognition (ie pattern-recognition) takes place in the nerve-plexus under the fingernail .

The survival advantages are obvious .
The primary advantage is in recognizing non-hostiles . False alarms are extremely wasteful , especially in hard times . A trinary classification at neural level  of hostile , neutral and friendly would evolve as an optimal solution .

There are circuits directly stimulating flight-or-fight mechanisms  . There is a direct tie to the hippocampus and amygdala through  stress proteins . There is a direct neural tie to muscles in the arm (from fingernails) and the legs (from toenails) .

This enabled the prey to identify a predator creeping or galloping up to it and take immediate reflex action .

Hyper-length neurons is the latest fashionable term to denote really long nervous connections without synapses .

The rich nexus of nerves under the fingernails have long been a target of human torture . But notice the aversion to nail-less humans or nail-biting . Notice how your attention is drawn to a nail-malformation (like a blue-nail)

2. Grooming.
Unarguably a defining social element in homonins .
But every human is complex of pressure waves .
Heartbeat , breathing , peritalsis  are only a few of the passive pressure-waves that can be sensed by fingertips . More active palpations enables joint-crackling , lung and abdominal spaces to be felt by fingertips . Ask any doctor .

By definition , some females would be better at fingertip sensitivity than others  . Since most infant mortality involves the gastro-intestinal system , which can be felt , sick babies allowed to be handled by the more sensitive woman are much more likely to survive . No language for this is needed initially .

Nursing and handling babies need sensitive touch .
Those females better at it ( ie well-shaped fingernails) evolve into  midwives , since they reduce infant mortality for the group .

The midwife is the first professional .

Indeed , the medical round has not changed much in about 70 000 years .

The dominant female shaman , surrounded by a cloud of students , stalks from infant to infant , subjecting them to tactile examination . Easily remedified complaints (like blockages) or tried and true herbal plants are used to reduce infant mortality . This information is transmitted to the students .

Note self-medication by chimps and gorillas .

3. What drives this language development ?
The problem with previous language-development models was that there is no really , really compelling evolutionary reason why language should evolve .

Hunters do not need it . Noise is contra-indicated . Modern warriors like the SEALs use sign language in combat .

Small-woman groups might have the tendencies , but how does being top-woman of a small , isolated group translate into a planetwide meme-and-gene dominance ?
We have to have a mechanism whereby local dominance is transmitted .

The Answer :
Old-Fashioned Darwin .
The reduction in infant-mortality  is the driver .
The transmission of information (ie language) then has an extremely direct relevance not only for a small tribe , but larger groups .

A tactile sensitive female with some language skill creates a positive feedback environment for higher infant survival rates . The language element enables her to teach students that scatter and repeat the process . The tribes that accept or send students to the college outbreed those that that don’t .

There is a crux point here relevant today :
Matriarchs (ie doctors) who tried to keep this advance in-tribe got overwhelmed by those that made it freely available .

Females , following an ancient imperative , would bring sick infants to the friendly neighborhood clinic .

The Matriarchal-Medical societal group outbred all others . And language was essential to the information transmission .


A bunch of doctors  huddling together and exchanging jargon is the origin of language. The jargon was expanded to include terms for social competition for resources and status . Language was born in all its glory .

Note that the invention of Peace
(See “The origins of war and Peace”)
is a logical consequence of the above scenario during a stress episode like Toba .
Not to mention the College / University idea . Which morphed into Organised Religion .

The Dark Side .
The Rite of Passage (ie to qualify to be seen as human and worthy of procreation ) was an invention simultaneous with the invention of Peace . Youths who could not subordinate their impulses (to fairness , pain , boredom ) to the society , were expelled from the procreational pool , or even killed .

This mechanism (meme-structure) is still active today . (Flunked Varsity ? You’re drafted.) Can’t stand the fraternity initiation ? You are not human . Go flip burgers .

This works fine as long as the governing society is in charge . But by expelling it’s mutants , the society builds up a pool resentful beings of various degrees of humanity.

A sudden change (climate , plague , technology , etc) reduces the defenses of the original system sufficiently to bring about a revolution

Ie the climatic stabilization about 12 900 years ago that made profitable agriculture possible .

4. Snakes .
The alert reader would have noticed that a reliable , sensitive temperature sensor is lacking in the human sensorium . The most sensitive ones are in the elbows and the back of the knees , and these hardly lend themselves to easy usage .

So they bred snakes . Remember , these are the people that domesticated through selective breeding all our present domesticated species .

Snakes then would have been the  very first domesticated species .

A living thermometer .

The infra-red sensors of snakes are more sensitive than present thermometers used in hospitals .

The specially bred snakes would have been bred not only for thermo-sensitivity , but for chemo-sensitivity as well .

The forked-tongue could detect not only breakdown products of illnesses exuded through the skin or breath , but location as well . (That’s why it’s forked.)

A basket of specialized snakes would enable a medical practitioner of the era
70 000 – 12 900 BC to give first level medical care equivalent to that of country clinic in our era . Diagnostics would have been superior , since specialized snakes would be doing this . Think programmed bio-chips .

Problem cases would be referred to the local College center .

Poisonous snakes was bred for medicinal aspects of their poisons (still being done today) .

So where are these snakes today ?
Traces of their genetic material should be found in garden snakes in Western Europe .
Obviously , nobody has looked for genetic bottlenecks from this viewpoint .

So this is a verifiable test .
Evidence of deliberate breeding (especially in mitochondrial snake DNA ) should be found  . It is doubtful that really highly specialized snakes could survive in the wild (think feral Jersey cow or Merino) , but some would have gotten lucky . Their genetic traces should be traceable .

Cultural remnants :
The Caduceus is a cultural remnant . (Intertwined snakes is still the Western symbol of medicine  .) Not bad for a symbol about 30 000 years old .

Legends , statues and inscriptions of dragons .

Bible : Eden . The snake got the starring role as the baddie , since the victors wrote the history books .

Also note Isis , purging of Ireland of snakes , Feng Shui , etc

Spirals : in rock engravings , etc . Which way does a snake coil up ?

Midwives .
The memes for this civilization is coiled up inside the one set of humans that had to survive : the midwives .

 Remember , they thought biologically . The concepts of seeds inside reproducing systems came naturally to them .

The Matriarchs  had thousands of years to see their demise coming and to plant seeds 

Ho-ho-ho !
The New World Order is guaranteed to be completely different from the Bilderbirger vision .

So , there were  some good ones matriarchs and some bad ones .

The good ones tried to ensure the survival of what was good in their civilization .

The bad ones tried to ensure their dominance .

The ensuing civil wars destroyed almost everything .

Most of the good got thrown out with the bad .

The planet is littered with the ruins of their buildings , bioforms and still-active
bio- weapon systems .

Some meme markers that have survived the wars :
Bio-warfare vs numbers . Fear the disease-ridden stranger . If you are not for us , you are against us . Any writing or symbol is dangerous , since it can contaminated with mind-altering vectors by touching it .

Some remnants of these have survived in central-europe : psychotic and schizophrenic inducing chemicals in basic foodstuffs like rye (ergot fungi) . Some very localized near the original labs .
 (One particular variant of psychosis inducing behavioural change organisms was localized within about 50 km radius  in central Europe : symptoms :  fear of persecution : paranoia with very definite cut-off points . A weapon .)

Your attention is drawn to plasmodium induced behaviour changes where the carriers are cats (and dogs as well) .
This would be a civilizing influence in a mild form ( taking risks by trusting ) , but a mind-control form in a strong form (trust unconditionally) . (Oxytocin stimulation)

A horrible thought is that the sites of the Nazi extermination camps (and the very idea) came from people picking up extermination bio-weapon contamination from old weapon sites . Note that the Nazi camps are on a line that would be a natural defensive line about 9 000 years ago .

Old weapons that kill and kill again .

Why the sudden sanity in the late twentieth century ?

Acid rain .

The vectors of madness were in the fungi (forest rhizomes) in the ground .
The weaponized mind-altering fungi , bacteria and viruses were obviously spread as widely as possible over the defensive lines . The ones that could survive thousands of years would be in the old fungi structures underground . These (because they were carrying a non-survival payload) were the first to die in acid-rain .

Remember , they thought like biologists .
They would not pick up a rock and bash you on the head . They would breed some organism that makes you vulnerable to their memes . You then would pick up a rock and bash their enemies ‘ heads in .

Can these organisms recover ?
Of course . They doing so now . See the latest history .

Why did this civilization nearly vanish ?
(See “The origins of war and Peace” , “Costs”  , “Nazca” , etc)

Your attention is drawn to the putative small comet impact on North America about 12 900 years ago . See New Scientist  26 May 2007 “Firestorm from space wiped out prehistoric Americans.”

This resulted in a short-term planetary climatic stability 
(alas , now coming to an end ).

The resulting climatic stability led to usable , profitable , large-scale agriculture .

This led to an explosion in human numbers .

The Matriarchy tried to keep the lid on  . Things got ugly on both sides .

The sub-human mutants (partially our ancestors ) won and extirpated their enemies . The late bronze-age cataclysm was but the end stages of a 7 000 year old clash of memes , and was correspondingly bitter.

Think Paris Hilton vs Bill Gates .

5 .Rhythm .

Rhythm is then a very ancient IFF mechanism .

Music is used as a cultural defining mechanism . Era’s and societies are defined by ephemeral harmonies .

If you like my rhythms  , we are pals .

6. Musical instruments:

Nearly all human instruments are characterized by causing compression waves around fingertips in sequences and cadences .

Guitar , piano , flute , etc .The reason why they popular is that they are easy to play . The reason why they are easy to play is that pattern-recognition takes place in the fingertips .

A hardwired threat is a cat stalking along slender bough . The cadence of a four-footed stalk is known . The damping of vibrations along a bough of decreasing diameter is known . The speed of the approach of the predator can then be calculated .

In music this translates as impending threat or doom . Can you see how it goes ?
Now you too can design threatening music that operates at instinctive level .

Finger tapping .
This is a variant of “Counting to ten” .
The pressure impacts on the nail-beds causes interrupts in the amygdale , hippocampus and lower stem .  Hence the success of some stress therapies using fingerclicking .

You got rhythm  if you fingertap and foot/toe tap with the music .

Fingertip to forearm tapping .
You will not find this little item anywhere else .

Endorphin release is proportional to fingertip-to-forearm cadences .

Instead of tapping your fingers on the table , tap them on and around your forearms instead in time to the music . Notice you will automatically start waving your forearms about .

Endorphin release is increased by orders  of magnitude .

Why ?

Your forearm is like a branch . You are tapping your fingertips and moving your hands and forearms in a way that signals “ Only friendlies and non-hostiles” about .

Monkey’s joy .

Listen to some music that has a beat . Put your right hand on your left forearm and vice versa . Tap your fingers on the forearms as if you are conducting like mad . Go mad .

Try it .

Notice the flatness if you stop . This is endorphin production being stopped .  (Especially with semi-classical music)

Notice that you move your fingers about 3 times as frequently as your thumbs . To be more exact , e=2.718… more frequently . The reason is obvious .

Notice that all musicians move their instruments if they can . The pianist moves his head and torso as he moves through the virtual canopy . Notice the contortions of a violinist . What does the virtual monkey-mind cluster of a violinist see as she contorts and gyrates ?

7. Counting .
The relationship between mathematics and music is well known .

But why ten fingers? Many different variations have been tried .
The answer is simple : 4 fingers + 1 thumb on each hand .
The thumb gives a better grasp on the branch . The 4 fingers at roughly equal distances split the harmonics of the wave on the branch . This is a physical optimization , inherent in the nature of vibrations . A physical and mathematical law of vibrations .

4=2^2  ,  8 = 2^4 . Can you see it ?

A little prediction : the spread of thickness of 4 fingers in homonids will optimize natural harmonies in branches of varying taper .

This means that the thumb is not strictly necessary for rhythm recognition . Notice that most instruments do not require the thumb except for grasping . (Eg the guitar : the right thumb is usually replaced by a plectrum.)
This also means that the thumb could be used for something else , and that is what evolutionary systems did . Thumb systems specialized in acting as reference point for the other fingers . A weight-lifter , javelin-thrower , tennis-player , golf-player , violin-player , etc all do the same thing : their hands analyze the vibration-characteristics of their instrument to find the sweet-spot relative to the other fingers .

8. Golf:
The monkey swings through the air and grips a branch .
The 4x2 fingers hook over to top . Immediately , IFF is done in the fingertips . If  no enemy is detected , the thumbs hook underneath . By this time , the branch has deformed under the weight and vibrations set up . Using the positions of the thumbs as reference points , the vibrational characteristics of the branch is analyzed . If the monkey wants to stay  and have a firm grip , it must move to a vibrational node of the branch (ie where the standing wave caused by it’s weight cancels out . Usually called the Sweet Spot .) . notice that one hand must get there first , usually overshooting . The overshooting hand is adjusted closer to the sweet spot , then the other hand . This approximation process is repeated until the monkey is satisfied (inside the parameter.)

It moves its hands , the fingers frequently and the thumbs less frequently (ratio of about 3 to 1) until it feels happy .

Now do the same to the golf club .
If right-handed , cradle the club lightly at balance point in the left hand with the fingers underneath and the thumb over the top , the handle to the right . The right hand has a light overhand grip .

Hold the club horizontal (like a branch ) , waggle it gently up and down . With the fingertips on the club , shift your hand alternately to the right until it feels correct . Jiggle the right hand back to correct for overshoot .

Then lock the right thumb in . (Note , locking the thumb is characteristic of all golf-grips . Now you know why .)

This is the interesting bit . While locking the right thumb in place , wriggle the left fingers and thumb until they feel ok . The right fingers can be wriggled as well , but not the right thumb . Do not wriggle the fingers more than 3 times the thumbs at this stage .

9. Piano

An interesting corollary is that you will learn the piano better and faster if you tape the thumbs out of the way .

10 .Birds .

So why doesn’t birds have ten toes ? They have 8 = 3x2 + 2.
Birds can fly , so they don’t have to stick around and develop enhanced harmonic analysis .

11. Stochastic resonance .

The Stochastic resonance mechanisms which evolved in the brain and hands to deal with random branch movements due to weather was essential to the development of language .

Lying and an honest error  cannot be distinguished from each other . And it does not matter in the long term .

12 .Sexual Selection.

Men look at women and see at a subconscious level :
1. Her middle/hip ratio is about 0.75 . Enough room for babies head
2.High , conical breasts . They will not smother baby while suckling and running .
3. Well-kept nails . Tactile sensitivity for baby care and nursing .

Women look at men and see at a subconscious level :
1. A taut bum . Good runner . Essential for good hunter .
2.Muscled arms . Good hunter and protector .
3. Symmetric face . Behaviour not too weird .

That’s it . The systems can only count to three .

If you want to overcome any negative impression on any one of these factors ,  you will have to work hard at it .

I was surprised to see nails pop out as an important sexual selection criterion . Females are always buffing , colouring , shaping , hardening , etc nails .

Shaped nails .
Refer to magnetrons . Shaped guides to various wave-forms can magnify the effect million-fold . Women with wave-guide shaped nails are remnants of the old order . Good or bad ? Unfortunately , nobody can tell . But if you run into one , run like hell .

The groove is only quantum deep , but it is coupled across all time .

So much for this space-time .


Appendix F

Scientists in the late 1970’s discovered another interesting tidbit about polar bears. A number of polar bears in zoos from around the world were turning green! These scientists discovered that the algae responsible for making the bears green were not on the SURFACE of the hairs, as originally supposed, but were INSIDE the hairs (Lewin & Robinson, 1979). The algae more than likely came from the pond waters in the bears’ enclosures.

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